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DTSTART;TZID=Europe/Paris:20260310T140000
DTEND;TZID=Europe/Paris:20260310T170000
DTSTAMP:20260302T132858Z
CREATED:20260210T161119Z
LAST-MODIFIED:20260302T132858Z
UID:51067-1773151200-1773162000@www.bricbordeaux.com
SUMMARY:Thesis defense Marianne Guilbard
DESCRIPTION:Thesis defense in Cancer Biology. \nMarianne Guilbard\, team 2 Oncogyne\, Frederic Delom \n“Tumor-adaptive functions of the secreted protein disulfide isomerase AGR2.” (thesis defense in french) \nTuesday\, March 10 at 2 p.m. \nBibliothèque\nInstitut Bergonié\, 229 cours de l’Argonne\, 33000 Bordeaux\, France \n\nNotice of thesis defense with abstract
URL:https://www.bricbordeaux.com/en/event/thesis-defense-marianne-guilbard/
LOCATION:Institut Bergonié\, 229 Cours de l'Argonne\, Bordeaux\, 33076\, France
CATEGORIES:Meetings,Scientific seminars,Thesis defenses
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2026/02/soutenance-de-these-marianne-guilbard.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260224T143000
DTEND;TZID=Europe/Paris:20260224T153000
DTSTAMP:20260226T151449Z
CREATED:20260202T151141Z
LAST-MODIFIED:20260226T151449Z
UID:50956-1771943400-1771947000@www.bricbordeaux.com
SUMMARY:Andreas Bikfalvi seminar - The complexity of causality in cancer: A scientific and philosophical investigation
DESCRIPTION:Andreas Bikfalvi\, Professor Emeritus at the University of Bordeaux\, affiliated with BRIC Team 1\, recently defended a thesis in philosophy at the Sorbonne He offers us a summary of this in this seminar. \n“The complexity of causality in cancer: A scientific and philosophical investigation” \n📅 Tuesday\, February 24\, 2:30 p.m. \n🚩 BBS (Bordeaux Biology Health) conference room – 2 rue du Dr Hoffmann Martinot Bordeaux (Carreire site\, University of Bordeaux) \nor by video conference \nAbstract \nMy work explores the complex nature of causality in cancer biology\, particularly within the tumor microenvironment (TME)\, integrating philosophical perspectives\, mathematical modeling\, and experimental data. It traces the evolution of cancer theories from cell-based to microenvironment-focused models\, highlighting increased complexity in causal interpretation due to tumor heterogeneity. The “Hallmarks of Cancer” framework is discussed as a descriptive tool that lacks causal clarity\, prompting the use of multi-scale and formal causal models. \nTwo main theoretical approaches—Somatic Mutation Theory and Tissue Organization Field Theory—are compared and integrated\, with probabilistic models illustrating the variable influence of genetics\, cellular environment\, and microenvironmental factors. Case studies on diffuse gliomas and clear cell renal carcinoma demonstrate how advanced causal modeling (using DAGs\, SEM\, and Bayesian approaches) can clarify the interplay among invasion\, immunity\, metabolism\, and genetic mutations. The research also identifies key molecular pathways and therapeutic targets. \nMethodologically\, the work highlights the challenges of validating complex causal networks and advocates for systematically integrating causal analysis in biomedical research. A holistic\, interdisciplinary approach is essential for advancing both fundamental understanding and clinical applications in oncology. Additionally\, it is shown how biomedical research can enhance philosophical conceptual analysis and philosophical concepts biomedical research \nBiosketch \nBorn in Hungary and raised in Germany\, I hold both French and German citizenships. I graduated in medicine in France and completed my residency in hematology and oncology at the University of Kiel (Germany). I then pursued a PhD in science at INSERM in Paris\, where my research focused on the biology of growth factors\, particularly FGFs\, and their role in regulating the phenotype of endothelial cells.  \nIn 1991\, I joined Professor Daniel B. Rifkin’s laboratory in New York\, where I studied the mechanisms of action of different molecular forms of FGFs. Upon returning to France in 1995\, I joined the CNRS and then the University of Bordeaux as a professor of cell and molecular biology\, where I established and led a laboratory dedicated to tumor and vascular biology\, affiliated with INSERM as of 2000. My unit became part of the BRIC INSERM center in Bordeaux in 2022 (Team 1 of BRIC) Since 2025\, I am an emeritus professor. Alongside my scientific activities\, I am also involved in philosophy of science and earned a doctorate in this field from Paris 1 Panthéon-Sorbonne. \n  \nSee the replay : \n[vc_video link=’https://youtu.be/2BnstxoRyEo’]
URL:https://www.bricbordeaux.com/en/event/andreas-bikfalvi-seminar-the-complexity-of-causality-in-cancer-a-scientific-and-philosophical-investigation/
CATEGORIES:Meetings,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2026/02/seminar-andreas-bikfalvi-24-02-2026.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20260131
DTEND;VALUE=DATE:20260201
DTSTAMP:20260120T165008Z
CREATED:20250625T130142Z
LAST-MODIFIED:20260120T165008Z
UID:50850-1769817600-1769903999@www.bricbordeaux.com
SUMMARY:Digestive Cancer Open Day 2026
DESCRIPTION:2026 Open Day on Digestive Cancers on Saturday\, January 31\, 2026. \nBRIC is once again holding an Open Day at its premises in Bordeaux\, on the Carreire campus (BBS building). Find information on our website dedicated to the general public:  \n  \npatient website \n  \nThis initiative\, which is fully in line with the goal of scientific outreach\, aims to introduce the general public\, in a variety of formats\, to the daily lives of researchers and recent advances in the field of digestive cancer research. The programme includes : \n\n\nContinuous reception (except from 12:30 p.m. to 1:45 p.m.)\n\n\n\nSeminars on the Cancer Research/Care and Innovation Ecosystem in the Region (11 a.m. and 2 p.m.)\n\n\n\nInteractive guided tours of the laboratory\, including 3 workshops:\n\nWorkshop: “Discovering Living Cells”\n\n\n\nWorkshop: “The journey of a sample”: from biopsy to treatment\n\n\n\nEscape Game Workshop\n\n\n\n\n\nWorkshops on “Observation of tumor tissues” (ongoing)\n\n\n\nExchange activity: “Ask all your questions” (ongoing)\n\n\n\nGuided discoveries into the mechanisms of cancer\, drug development\, and various therapies. (ongoing)\n\n\n\nStand of the Gironde Cancer League (continuous)\n\n\n\nDiscovery of a biological model (ongoing)\n\n\nTours departing with workshop participation at 10 a.m.\, 11 a.m.\, 2 p.m.\, and 3 p.m. Other activities ongoing throughout the day. \n\nCome and discuss\, around posters or mini-seminars\, with various contributors involved in the research: – Academic research professionals (researchers and teacher-researchers\, engineers and technicians\, doctoral students and interns) – Clinical research professionals – Clinicians\, including surgeons and oncologists \n\nPatient associations\, including La Ligue Contre le Cancer de Gironde (the Gironde Cancer League) and a start-up company spun off from the laboratory\, will also be present! \n\nCome visit the laboratory and take the opportunity to put on a lab coat and gloves and participate in fun workshops! This project is led by teams 3\, 4\, and 8 at BRIC\, in collaboration with several supervisory bodies (Inserm\, University of Bordeaux) and scientific partners: (Bordeaux University Hospital\, OncoProt\, BeLiver\, Bergonié Institute). \n  \nAccess: \n🚘Apart from the parking spaces reserved for university staff (badge required)\, you will find spaces closer by on the sidewalk along the wall on Rue du Dr Hoffmann Martinot. Otherwise\, there is a parking lot reserved for visitors a 5-minute walk away\, located at 125 Bethmann Street. \n🚊Take tram A to the Saint Augustin stop\, then follow the “cycles et piétons” (cycles and pedestrians) markings on the ground across the CHU campus. \n🚍Several bus lines nearby\, see location map \n  \nlocation map
URL:https://www.bricbordeaux.com/en/event/digestive-cancer-open-day-2026/
LOCATION:Accueil bâtiment Bordeaux Biologie Santé (BBS)\, 2 rue Dr Hoffmann Martinot\, Bordeaux\, France
CATEGORIES:Meetings,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2025/06/vignette-jpo-cancers-digestifs-bric-31-01-2026.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260127T140000
DTEND;TZID=Europe/Paris:20260127T150000
DTSTAMP:20260106T111830Z
CREATED:20260106T111830Z
LAST-MODIFIED:20260106T111830Z
UID:50730-1769522400-1769526000@www.bricbordeaux.com
SUMMARY:Invited Seminar Kevin Boyé
DESCRIPTION:We invite Kevin Boyé to give a seminar open to the scientific community. \nDr. Kevin Boyé\nCRCN INSERM Paris Cardiovascular Research Center – 56 Rue Leblanc\, 75015 Paris\nCo-founder of D2B3 – 101 College Street\, 06511 New Haven\, CT\, USA \n \n“Unlocking the Blood–Brain Barrier during Glioblastoma progression” \n📆 Tuesday\, January 27\, 2 p.m.\n🚩 BBS Conference Room\, 2 rue Dr Hoffmann Martinot\, Carreire site\, University of Bordeaux \nAbstract \nBlood vessels in the brain form 600 kilometers of specialized blood-brain barrier (BBB) that protect the brain from toxins and pathogens\, thereby ensuring homeostasis and proper neurological function. However\, BBB impermeability also severely limits brain drug delivery during many neurological disorders. \nGlioblastoma (GBM) is the most aggressive primary brain tumor with a median survival of 12–15 months. Although BBB integrity is partially disrupted within the tumor core\, the highly invasive nature of GBM cells into the BBB-competent brain parenchyma strongly limits the delivery and efficacy of therapeutic molecules\, leading to inevitable recurrence after surgical resection. Hence\, developing tailored therapeutic strategies that can transiently and safely modulate BBB permeability without compromising its protective function remains a major unmet clinical need. \nWe recently identified the endothelial receptor Unc5B and its ligand Netrin-1 as central regulators of BBB integrity. Single-cell RNA sequencing revealed that this pathway controls a core BBB gene expression program of over 100 genes involved in tight junction organization\, nutrient and ion transport\, and efflux pump function. To harness this mechanism therapeutically\, we developed\, optimized\, and patented a fully human monoclonal antibody (Anti-Unc5B) that specifically blocks Netrin-1 binding to Unc5B. \nFollowing intravenous injection\, Anti-Unc5B induces a brain-wide and brain-specific\, opening of the BBB for up to six hours\, prior to barrier resealing. This transient permeability window is size-selective\, cumulative and safe. Using this BBB-permeabilizing strategy\, we could enhance the delivery and efficacy of a wide variety of therapeutic molecules including chemotherapies\, tyrosine kinase inhibitors and nanobodies during GBM progression\, resulting in increased tumor cell apoptosis\, reduced tumor growth and improved survival. \nBiosketch \nI completed my PhD in the laboratory of Pr. Andreas Bikfalvi under the supervision of Dr. Clotilde Billottet (INSERM U1029\, France)\, where I identified the chemokine receptor CXCR3-A and its ligand CXCL4L1 as a novel signaling pathway essential for brain tumor progression (Boyé K. et al.\, Nature Communications 2017; Boyé K. et al.\, Scientific Reports 2017; Quemener C et al. Cancer Research 2016). However\, like most therapeutic molecules developed for neurological diseases\, intravenously injected CXCR3-A inhibitors were unlikely to efficiently cross the blood–brain barrier (BBB). \nTo overcome this limitation\, I joined the laboratory of Pr. Anne Eichmann at Yale University (New Haven\, USA) as a postdoctoral fellow (2017-2022)\, where I investigated mechanisms regulating vascular barrier integrity (Genet G.\, Boyé K. et al. Nature Communication 2019; Zhang F. et al. Science 2018)\, with a particular focus on the BBB (Boyé K. et al.\, Nature Communications 2022). I identified the endothelial Unc5B receptor and its ligand Netrin-1 as a key signaling pathway required to maintain BBB integrity. I subsequently developed a human monoclonal antibody that block Netrin-1 binding to Unc5B\, enabling a reversible and controlled BBB opening leading to brain delivery of bioactive molecules (Two Patents in 2023). \n  \nSince 2023\, I am a Group Leader (CRCN) at the Paris Cardiovascular Research Center (INSERM U970). My group is currently funded by an FRM “Amorçage jeunes équipes” (2023-2026)\, an ANR PRC (Coordinator; 2026 – 2028) and an INCa PLBIO (Coordinator; 2026 – 2028). My research program focuses on: \n\nOptimizing brain drug delivery beyond the BBB during brain tumor progression.\nEnhancing BBB integrity in diseases with BBB dysfunction.\n\nWe recently reported a BBB gene-expression program zonated along the arteriovenous axis that can be tuned to increased brain drug delivery (Furtado et al.\, PNAS 2024). \n  \nIn 2024 I co-founded D2B3 (https://d2b3.bio)\, a start-up company spun out of Yale University\, aiming to improve brain drug delivery in patients using our patented BBB-permeabilization technology.
URL:https://www.bricbordeaux.com/en/event/invited-seminar-kevin-boye/
LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux
CATEGORIES:Meetings,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2026/01/invited-seminar-kevin-boye-27-01-2026.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251218T140000
DTEND;TZID=Europe/Paris:20251218T170000
DTSTAMP:20251216T160428Z
CREATED:20251216T160142Z
LAST-MODIFIED:20251216T160428Z
UID:50583-1766066400-1766077200@www.bricbordeaux.com
SUMMARY:Thesis defense Zahraa FAKIH - team 05
DESCRIPTION:Thesis defense in Cell Biology and Physiopathology of Zahraa FAKIH \n🎤 Études Moléculaires des Anomalies de Pigmentation dans Le Xeroderma Pigmentosum de Type C\nThesis supervisor : Muriel CARIO équipe 5 – Recherche translationnelle en cancérologie cutanée et maladies cutanées rares (TRIO2). \n📅 Thursday\, December 18\, 2025\, 2:00 p.m.\n🚩 salle de conférence BBS – 2 rue Docteur Hoffman Martinot\, Site Carreire\, 33000\, Bordeaux \n  \nnotice of defense with summary
URL:https://www.bricbordeaux.com/en/event/thesis-defense-zahraa-fakih-team-05/
LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux
CATEGORIES:Meetings,Scientific seminars,Thesis defenses
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2025/12/soutenance-de-these-zahraa-fakih2.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251217T140000
DTEND;TZID=Europe/Paris:20251217T170000
DTSTAMP:20251211T163743Z
CREATED:20251211T163046Z
LAST-MODIFIED:20251211T163743Z
UID:50556-1765980000-1765990800@www.bricbordeaux.com
SUMMARY:Thesis defense Lucile Rouyer\, team 3
DESCRIPTION:Thesis defense in Cancer Biology by Lucile Rouyer\, team 03 – Liver Cancers and Tumor Invasion \n\n\n\n\nThesis supervisor : Frederic Saltel \n“Étude et modélisation in vitro des interfaces au cours de la progression tumorale.” \n\n\n\n\n📅 Wednesday\, December 17\, 2 p.m. \n\n\n🚩 Amphi BBS\, campus Carreire\, Université de Bordeaux \n\n\n\n  \nnotice of defense with summary
URL:https://www.bricbordeaux.com/en/event/thesis-defense-lucile-rouyer-team-3/
LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux
CATEGORIES:Meetings,Scientific seminars,Thesis defenses
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2025/12/soutenance-de-these-lucile-rouyer.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251217T140000
DTEND;TZID=Europe/Paris:20251217T170000
DTSTAMP:20251211T161633Z
CREATED:20251211T160926Z
LAST-MODIFIED:20251211T161633Z
UID:50546-1765980000-1765990800@www.bricbordeaux.com
SUMMARY:Thesis defense by Ferial KHALIFE\, team 5.1
DESCRIPTION:Thesis defense in Cancer Biology by Ferial KHALIFE\, team 5.1 Skin carcinomas\, Photoprotection\, Metabolism \nThesis supervisor Hamid-Reza Rezvani. \nTitle : Ciblage thérapeutique de la vulnérabilité métabolique des carcinomes épidermoïdes cutanés. \n📅 Wednesday\, December 17\, 2 p.m. \n🚩 Module 1.1\, campus Carreire\, bâtiment CROUS\, 1er étage\nUniversité de Bordeaux\, 146 Rue Léo Saignat\, 33000 Bordeaux \nnotice of defense with summary
URL:https://www.bricbordeaux.com/en/event/thesis-defense-by-ferial-khalife-team-5-1/
CATEGORIES:Meetings,Thesis defenses
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2025/12/soutenance-de-these-ferial-khalife.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251212T140000
DTEND;TZID=Europe/Paris:20251212T170000
DTSTAMP:20251208T174943Z
CREATED:20251208T174136Z
LAST-MODIFIED:20251208T174943Z
UID:50523-1765548000-1765558800@www.bricbordeaux.com
SUMMARY:Thesis defense: Thibaut Matis - Team 8
DESCRIPTION:Thesis defense in Genetics of Thibaut Matis\, team 8 – Biotherapies Genetics and Oncology (BioGO) \n\n\n\n\n“CISCO : Etude des régions CIS régulatrices de l’expression du gène PTEN et leur implication dans la maladie de COwden.” \nThesis supervision : Nicolas Sevenet \n\n\n\n\n📆 Friday\, December 12\, 2 p.m \n\n\n🚩 Lecture Hall 12\, Carreire Campus\, 146 rue Leo Saignat Bordeaux (To find Lecture Hall 12 from the BBS\, follow the map) \n\n\n\nnotice of defense with summary \n 
URL:https://www.bricbordeaux.com/en/event/thesis-defense-thibaut-matis-team-8/
LOCATION:amphi 12\, site Carreire\, 146 rue Leo Saignat\, Bordeaux
CATEGORIES:Meetings,Scientific seminars,Thesis defenses
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2025/12/soutenance-de-these-thibaut-matis.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251210T140000
DTEND;TZID=Europe/Paris:20251210T170000
DTSTAMP:20251204T164723Z
CREATED:20251204T163408Z
LAST-MODIFIED:20251204T164723Z
UID:50495-1765375200-1765386000@www.bricbordeaux.com
SUMMARY:Thesis defense Lea Pechtimaldjian\, team Trio2
DESCRIPTION:Soutenance de thèse de Léa Pechtimaldjian\, équipe Equipe: 5.2 Cutaneous lymphomas\, Vascular tumors\, Tissue engineering (M. Beylot-Barry\, L. Bresson-Bepoldin) \nTitre de thèse: “Etudes des télocytes cutanés dans l’hémangiome infantile: caractérisation\, propriétés angiogéniques et approches thérapeutiques” \nSpécialité: Biologie cellulaire et physiopathologie \nDirecteur de thèse: François Moisan \nMercredi 10 décembre 2025\, 14h\nAmphi BBS\, 2 rue Dr Hoffmann Martinot Bordeaux \n  \nnotice of defense with summary
URL:https://www.bricbordeaux.com/en/event/thesis-defense-lea-pechtimaldjian-team-trio2/
LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux
CATEGORIES:Meetings,Scientific seminars,Thesis defenses
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2025/12/soutenance-de-these-lea-pechtimaldjian.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251210T110000
DTEND;TZID=Europe/Paris:20251210T120000
DTSTAMP:20251204T154347Z
CREATED:20251204T154347Z
LAST-MODIFIED:20251204T154347Z
UID:50485-1765364400-1765368000@www.bricbordeaux.com
SUMMARY:Invited seminar Bernhard Wehrle-Haller
DESCRIPTION:On the occasion of Léa Pechtimaldjian‘s thesis\, Team 5 (TRIO2) invites Bernhard Wehrle-Haller\, member of the jury\, to present a seminar to the scientific community. \nBernhard Wehrle-Haller PhD\nUniversity Medical Center\, Geneva\, Switzerland \n“The multiple roles of integrins in the assembly of fibronectin fibrils in the tumor stroma” \nAbstract:\nThe formation and growth of tumors depends on oxygen supply\, but also on mechanical support through increased synthesis of the extracellular matrix. Increased extracellular matrix stiffness enhances the survival capacity of tumor cells under therapeutic stress. At the same time\, tumor cells stimulate host cells to produce a supportive extracellular matrix. The mechanisms of this feedback are not well understood\, and there is no treatment to reverse the fibrotic response in the tumor stroma. Since integrins are essential receptors for tumor binding to the extracellular matrix\, but are also involved in the synthesis of extracellular matrix fibers\, we asked about the nature of intracellular connections and intracellular signaling that control how integrins are used by tumor or stromal cells in tumors. In a clinical approach\, we analyzed different types of glioblastoma to better understand the physiological roles of integrins in this type of cancer. \nBiography:\nStudied biochemistry in Basel\, Switzerland; Thesis in the field of extracellular matrix (tenascin\, laminin\, fibronectin\, and neurite growth)\, Biozentrum Basel\, Switzerland; Postdoc: in Oregon\, US\, directional migration of embryonic melanoblasts and role of growth factors; Return to Switzerland\, Geneva\, then appointment as Associate Professor\, role of integrin family receptors in cell adhesion and migration.  \n  \n 
URL:https://www.bricbordeaux.com/en/event/invited-seminar-bernhard-wehrle-haller/
LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux
CATEGORIES:Meetings,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2025/12/bernhard-wehrle-haller-2025-12-10.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251208T140000
DTEND;TZID=Europe/Paris:20251208T150000
DTSTAMP:20251107T144403Z
CREATED:20251107T142441Z
LAST-MODIFIED:20251107T144403Z
UID:50347-1765202400-1765206000@www.bricbordeaux.com
SUMMARY:Imaging presentation: CRYO-FIB-SEM - 08-12-2025
DESCRIPTION:What is the purpose of a CRYO-FIB-SEM in Biology and Biomaterials in Bordeaux? (Présentation en français)\nEtienne Gontier\, PhD.\nResponsable BIC – Electronique\nIngénieur de recherche HC\nBordeaux Imaging Center\n\n\nAbstract:\n\nA cryoFIBSEM is a high-resolution scanning electron microscope equipped with a focused ion beam (FIB) column and a cryo-observation stage. In addition to being a conventional SEM\, samples can be imaged in 3D to obtain high-resolution volumes (3nm voxel) after abrasion using the FIB beam\, with or without correlative microscopy. It is also possible to generate these volumes from vitrified samples and capture the 3D ultrastructure in a state close to its native state. In addition\, soft materials such as polymers\, biological samples\, and many other systems can deform\, melt\, or become amorphous under FIB milling and SEM imaging conditions at room temperature. Thanks to cryo-FIB/SEM\, the sample is cooled to cryogenic temperatures (-130°C) in order to minimize these artifacts. This allows FIB cross-sections and SEM images to be produced with +/- chemical analysis of beam-sensitive materials\, with minimal deformation. Finally\, this technology enables\, among other things\, the preparation of cryogenic FIB lamellae for cryo-MET analysis.\n\nThe aim of this presentation will be to introduce this comprehensive\, innovative new electron microscopy equipment\, which is new to Bordeaux and the surrounding region. Thus\, initially\, the context in which this purchase is being made and the technological aspects will be explained. Next\, and most importantly\, the various possible applications will be presented in the form of concrete examples. We will conclude with a discussion.
URL:https://www.bricbordeaux.com/en/event/imaging-presentation-cryo-fib-sem-08-12-2025/
LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux
CATEGORIES:Meetings
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2025/11/presentation-bic-cryo-fib-sem-08-12-2025.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251125T140000
DTEND;TZID=Europe/Paris:20251125T170000
DTSTAMP:20251124T163517Z
CREATED:20251124T160643Z
LAST-MODIFIED:20251124T163517Z
UID:50424-1764079200-1764090000@www.bricbordeaux.com
SUMMARY:Thesis defense by Yasmine Pobiédonoscew - Team 11
DESCRIPTION:Thesis defense in Cancer Biology. \nYasmine POBIEDONOSCEW\, team 11 \nWork supervised by Ms. Béatrice TURCQ \nIdentification des cellules souches leucémiques de la leucémie myéloïde chronique dans un nouveau modèle murin. \n  \n  \nNotice of defense with summary and jury \n  \n📆 Tuesday\, November 25\, 2 p.m. \n🚩Salle de conférence – Centre d’Appui à la Recherche et de Formation (CARF) 146 rue Léo Saignat 33000 Bordeaux
URL:https://www.bricbordeaux.com/en/event/thesis-defense-by-yasmine-pobiedonoscew-team-11/
CATEGORIES:Meetings,Thesis defenses
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2025/11/soutenance-de-these-yasmine-pobiedonoscew.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251124T170000
DTEND;TZID=Europe/Paris:20251124T200000
DTSTAMP:20251124T155117Z
CREATED:20251124T155117Z
LAST-MODIFIED:20251124T155117Z
UID:50422-1764003600-1764014400@www.bricbordeaux.com
SUMMARY:HDR defense Audrey Michot team 9
DESCRIPTION:Audrey Michot\, MD\, PHD will defend her HDR (Habilitation à Diriger la Recherche\, or accreditation to supervise research)\, specializing in Life and Health Sciences. \nTitle : Optimisation de la prise en charge des sarcomes des tissus mous : de la prédiction des rechutes à l’innovation chirurgicale. \nMonday\, November 24\, 5 p.m. \nInstitut Bergonié 229 cours de l’Argonne 33000 Bordeaux
URL:https://www.bricbordeaux.com/en/event/hdr-defense-audrey-michot-team-9/
LOCATION:Institut Bergonié\, 229 Cours de l'Argonne\, Bordeaux\, 33076\, France
CATEGORIES:Meetings,Thesis defenses
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2025/11/soutenance-hdr-audrey-michot-24-11-2025.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20251122
DTEND;VALUE=DATE:20251123
DTSTAMP:20251124T163138Z
CREATED:20251117T182019Z
LAST-MODIFIED:20251124T163138Z
UID:50419-1763769600-1763855999@www.bricbordeaux.com
SUMMARY:Research Opens Its Doors #3 - BRIC Participation
DESCRIPTION:Our BRIC Unit participates in the SBM Department Open House \nCome and meet them! \n📆Saturday\, November 22\n🕑9h15 à 12h30 and 14h à 17h\n🚩bâtiment BBS\, 2 rue Dr Hoffmann Martinot Bordeaux (plan d’accès) \n  \nAll information about this event \n  \nMeet the scientists from our unit at these tours and workshops: \nVISITS: \n“Les supers pouvoirs des cellules” : Lamia Azzi-Martin\, Clotilde Billottet\, Arnaud Jabouille\, Martina Carlotti \n“Venez découvrir votre ADN” : Christelle Dussert\, Valérie Le Morvan\, Coralie Genevois \n“Visite d’un laboratoire de recherche” : Christine Varon\, Magalie Lalanne \n“Rencontre avec un habitant de l’estomac” : Lucie Bruhl\, Astrid Ducournau\, Jessica Massière \n“Formule 1… En rouges et Blancs” : Elodie Richard\, Valérie Lagarde \n  \nPOSTERS \nLaurence Bresson-Bepoldin et Sandrine Fedou \n  \nWORKSHOPS \nAtelier microscopie : Vanessa Desplat\, Lucie Brisson \nAtelier “Les métiers de la Recherche” : Isabelle Vigon\, Lucie Brisson \nAtelier “Les ciseaux de l’ADN” : Valérie Prouzet\, Béatrice Turcq \nAtelier “Un poisson nommé Danio” : Géraldine Siegfried\, Elodie Muzotte\, Sandrine Fedou \nAtelier pour les enfants : Lisa Renaudet-Keller \n  \nWelcome/Departure group \nLaurence Bresson Bepoldin\, Céline Léon\, Grégoire Manaud\, Lindita Lari\, Blandine Vignau\, Anne Berger\, Ana Sofia Uriola Vasquez\, Rémi Darracq\, Amandine Rousselle\, Anne Lhuillery\, Clara Jollet\, Lucie Gouret\, Melissa Correia de Oliveira\, Nina Choublier \n  \n👏Bravo à tous pour votre participation à cette journée ouverte à tous !
URL:https://www.bricbordeaux.com/en/event/research-opens-its-doors-3-bric-participation/
LOCATION:Accueil bâtiment Bordeaux Biologie Santé (BBS)\, 2 rue Dr Hoffmann Martinot\, Bordeaux\, France
CATEGORIES:Meetings
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2025/11/vignette-jpo-departement-sbm-22-11-2025.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251114T140000
DTEND;TZID=Europe/Paris:20251114T150000
DTSTAMP:20250729T144312Z
CREATED:20250729T144312Z
LAST-MODIFIED:20250729T144312Z
UID:49802-1763128800-1763132400@www.bricbordeaux.com
SUMMARY:Invited seminar Etienne Brecht & Aurélie Beaufrère - 2025-11-14
DESCRIPTION:Marion Bouchecareilh et Samuel Amintas from Team 8 “Genetic Biotherapies and Oncology” (BioGO) invite two speakers from Paris Cité University\, Center for Inflammation Research\, INSERM 1149\, Sinkus Team (From micro to macro in cancer development) for this seminar open to the scientific community. \n👉 Aurélie Beaufrère \nMorphological and molecular heterogeneity of hepatocellular carcinoma. \nAbstract:\nHepatocellular carcinoma is the most common primary malignant liver tumor. This tumor is highly heterogeneous\, both morphologically\, with eight histological subtypes described\, and molecularly\, with distinct transcriptomic groups described that are linked to both genomic alterations and morphological aspects. Some of these characteristics impact both prognosis and response to treatment.   \nBiography:\nCurrently an MCU-PH in the Pathology Department at Beaujon Hospital\, my hospital and research work focuses on liver pathology\, particularly liver tumors. I am developing projects on the morphological and molecular heterogeneity of primary liver tumors\, as well as multimodal artificial intelligence projects integrating pathological\, radiological\, and molecular data.  \n  \n👉 Etienne Becht \nHigh-throughput single-cell quantification of 100s of proteins using conventional flow cytometry and machine learning. \nAbstract: \nTechniques enabling single-cell resolution proteomic analyses are limited in terms of the number of cells analyzed and/or the number of proteins measured. To overcome these limitations\, we have developed “Infinity Flow\,” a method for analyzing flow cytometry data in parallel using machine learning models. By enabling the pseudo-quantification of hundreds of proteins in millions of single cells\, this technique allows for in-depth mapping of the microenvironment of complex tissues. We are currently applying it to the study of liver cirrhosis and hepatocellular carcinoma.    \nBiography: \nAs an engineer by training\, I completed a thesis in cancer immunology under the joint supervision of Hervé Fridman (PUPH) and Aurélien de Reyniès (bioinformatician) at the Cordeliers Research Center in Paris. There\, I developed MCP-counter\, a method for estimating the composition of the tumor microenvironment from the bulk transcriptome. I then completed two postdoctoral fellowships\, first at the Singapore Immunology Network on mass cytometry data analysis\, then in Seattle on parallelized flow cytometry data analysis. I then worked in R&D at Servier (Computational Medicine team) before joining Valérie Paradis’ laboratory at the hospital as an INSERM research fellow. My project focuses on profiling the hepatic microenvironment using parallelized flow cytometry and developing bioinformatics methods for analyzing cytometry data.     \n 
URL:https://www.bricbordeaux.com/en/event/invited-seminar-etienne-brecht-aurelie-beaufrere-2025-11-14/
LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux
CATEGORIES:Meetings,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2025/07/seminaire-e-brecht-aurelie-beaufrere-2025-11-14.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251113T100000
DTEND;TZID=Europe/Paris:20251113T113000
DTSTAMP:20251031T135221Z
CREATED:20251031T135221Z
LAST-MODIFIED:20251031T135221Z
UID:50307-1763028000-1763033400@www.bricbordeaux.com
SUMMARY:Graduate program Cancer Biology invited seminar - Raul V. DURAN
DESCRIPTION:The lecturers and professors of the Graduate Program in Cancer Biology invite Raul V. Duran to give a lecture in Bordeaux on Thursday\, November 13\, from 10:00 a.m. to 11:30 a.m. in the conference room of the BBS building\, 2 rue du Dr Hoffmann Martinot.\nRaul Duran will be available on Wednesday\, November 12\, during the morning\, to talk with researchers who wish to meet him.\nContact: jose-eduardo.gomes@u-bordeaux.fr\n\n\nRaul V. Duran\nSpanish National Research Council (CSIC) – Séville\nGroup Leader of the Group of Metabolism and Cell Signaling\n \n“Metabolic imbalance as a therapeutic strategy in cancer.” \n  \nAbstract \nDuring last years\, a great amount of effort has been dedicated to elucidate the crosstalk between cellular metabolic and bioenergetic flows with signaling processes\, and how this interaction contributes to coordinate the growth and homeostasis of cells and tissues. Particularly\, how these interaction mechanisms are deregulated in cancer at the molecular and cellular level is a matter of intense research\, with the aim of using this knowledge to propose new therapeutic alternatives. Our research has established the processes of interaction between the metabolism of the amino acid glutamine\, the most abundant in human blood and the most important from an energetic point of view for cells\, with cell signaling via the mTOR pathway\, a protein complex essential in the regulation of cell growth and metabolism\, and autophagy. More recently\, we focused our research on metabolic adaptation associated to therapy resistance in glioblastoma (GBM)\, one of the tumor types with the poorest survival outcomes. This work resulted in the identification of FGFR1 pathway as a major regulator of the signaling and metabolic rewiring associated with temozolomide (TMZ) resistance in GBM. Hence\, we described a mechanism of resistance that operates at two major levels. First\, a p53-mediated regulation of cell cycle inducing cell cycle arrest to allow DNA repair in response to TMZ. And second\, a complete metabolic rewiring promoting lipid catabolism and preventing lipid peroxidation. Both the p53-mediated response and the metabolic adaptation are controlled by FGFR1\, as inhibition of the FGFR1 pathway completely abolishes this signaling and metabolic reprograming\, restoring sensitivity to TMZ. Our results also indicated a correlation of FGFR1 activity with poor prognosis in GBM patients\, and validated the treatment of TMZ in combination with FGFR1 inhibitors as an efficient strategy to induce tumor cell death in pre-clinical animal models. This data position the receptor FGFR1 as a very promising candidate for evaluation in future clinical approaches to limit the development of therapy resistance to TMZ in GBM patients. \n  \nBiosketch \nI obtained my PhD in Biochemistry at the University of Seville (Spain) in 2005 working on cellular bioenergetics. Then\, I joined the lab of Prof. Eyal Gottlieb at the Beatson Institute for Cancer Research (Glasgow\, UK) as a postdoctoral researcher to extend my expertise on broader aspects of cancer metabolism. Later\, I moved to the lab of Prof. Michael N. Hall at the Biozentrum (Switzerland) as a senior postdoc to study the de-regulation of cellular signaling during cancer. In 2013 I joined the Institut Européen de Chimie et Biologie (Pessac\, France) as a Group Leader (INSERM\, CR position)\, integrating my previous expertise to investigate the crosstalk between metabolism and cell signaling in cancer cells. In 2018 I moved my lab to the Centro Andaluz de Biología Molecular y Medicina Regenerativa – CABIMER\, upon my assignment as Senior Research Associate (Científico Titular) at CSIC. Since them\, I am the Group Leader of the Group of Metabolism and Cell Signaling\, and in the period 2019-2022 I was the Director of the Department of Dynamics and Cell Signaling at CABIMER. In the period 2020-2024 I was the Deputy Director of CABIMER. Currently\, I am a member of the Executive Committee of the CONEXION CANCER-CSIC\, and I serve as Associate Editor of the journal Cancer & Metabolism. Since January 2025 I serve as permanent evaluator (Gestor) of the Spanish Agency of Investigation (AEI)\, in the Biomedicine – Cancer commission.
URL:https://www.bricbordeaux.com/en/event/graduate-program-cancer-biology-invited-seminar-raul-v-duran/
LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux
CATEGORIES:Meetings,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2025/10/seminaire-invite-graduate-schhol-cancer-raul-v-duran.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251023T103000
DTEND;TZID=Europe/Paris:20251023T113000
DTSTAMP:20250929T081714Z
CREATED:20250929T081714Z
LAST-MODIFIED:20250929T081714Z
UID:50101-1761215400-1761219000@www.bricbordeaux.com
SUMMARY:Invited seminar Thamil Selvee Ramasamy - 23-10-2025
DESCRIPTION:Thamil Selvee Ramasamy\nStem Cell Research Laboratory\, Department of Molecular Medicine\, Faculty of Medicine\, Universiti Malaya\, Kuala Lumpur\, MALAYSIA. \nInvited by Delphine Fessart and the Oncology and Gynaecology (OncoGyne) Laboratory head by Frederic Delom \nThursday\, October 23 at 10:30 a.m.\, BBS conference room\, 2 rue du Dr Hoffmann Martinot \nStem Cell Plasticity in Developmental Biology\, Regenerative Medicine and Cancer \nShort biosketch: Dr. Ramasamy earned her PhD in Clinical Medicine Research Programme (specialisation: human embryonic stem cell research) from Imperial College London\, UK. She is currently serving as an associate professor at the Department of Molecular Medicine and heading the Stem Cell Biology Laboratory at Universiti Malaya\, Malaysia. Exploring the potential of stem cells in development of therapy for degenerative diseases and targeting cancer stem cells are the primary focus of her research. More details can be found in her page: umexpert.um.edu.my/selvee.html and Web of Science Researcher IDF-3044-2012. \n\nAbstract  \nStem cell plasticity is the key concept in developmental biology\, enabling the zygote and inner cell mass to give rise to all 208 specialized cell types through exquisitely precise signalling and cell–cell communication. I will share on how embryonic stem cells can be used to understand and engineer cell fates\, focusing on my work on neuronal and hepatic differentiation. Both embryonic and adult stem cells offer a versatile reservoir for generating therapeutically relevant cells in regenerative medicine\, this talk will cover the work done in our laboratory on developing regenerative therapies using stem cells in combination with other approaches.  \nIntriguingly\, in oncology\, cancer stem cell plasticity fuels tumour heterogeneity\, therapy resistance\, and relapse\, presenting persistent challenges for effective treatment. In the interest of BRIC researchers\, I will devote most of my talk to how we model cancer stem cells in culture\, using these models to unravel the molecular regulation governing plasticity in malignant contexts\, with a particular focus on hepatocellular carcinoma. Since the direction of our current work aims to leverage cutting-edge technologies including spatial transcriptomics\, nanotechnology-based drug delivery\, drug repurposing\, and cancer immunotherapy to intercept cancer stem cell plasticity and advance precision oncology\, I would like explore your expertise and discuss potential collaborations with BRIC researchers in this domain. \n  \nContact to meet Thamil Selvee Ramasamy : Delphine Fessart : delphine.fessart@inserm.fr
URL:https://www.bricbordeaux.com/en/event/invited-seminar-thamil-selvee-ramasamy-23-10-2025/
LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux
CATEGORIES:Meetings,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2025/09/thamil-selvee-ramasamy-2025-10-23-v2.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251013T090000
DTEND;TZID=Europe/Paris:20251013T130000
DTSTAMP:20250925T093649Z
CREATED:20250925T093649Z
LAST-MODIFIED:20250925T093649Z
UID:50143-1760346000-1760360400@www.bricbordeaux.com
SUMMARY:Thesis defense by Chloé Redouté-Timonnier
DESCRIPTION:Chloé Redouté-Timonnier\n\, team 6 MIRCADE will defend her thesis in cancer biology on Monday\, October 13\, at 9 a.m. in the lecture hall of the Bordeaux Biology Health (BBS) building at the University of Bordeaux – 2 rue du Dr Hoffmann Martinot\, Bordeaux. \nImpact des isoformes DDR1a et DDR1b sur le développement du carcinome rénal à cellules claires (ccRCC). \nThesis supervisor Patrick Auguste. \nSummary in the defense notice at this link \nJury members:\nM. Ulrich VALCOURT – Laboratoire de Biologie Tissulaire et Ingénierie Thérapeutique (LBTI) UMR 5305 CNRS et Université Claude Bernard Lyon 1\, Rapporteur\nM. Curzio RUEGG – University of Fribourg\, Switzerland\, Rapporteur\nMme Elisabeth GENOT – Bioingénierie Tissulaire (BioTis) Inserm U1026 Université Bordeaux\, Examinatrice\nM. Hamid MORJANI – BioSpectroscopie Translationnelle BioSpecT – EA7506 UFR de Pharmacie – Université deReims\, Examinateur\nMme Isabelle SAGOT – IBGC UMR 5095 – Université de Bordeaux\, Examinatrice
URL:https://www.bricbordeaux.com/en/event/thesis-defense-by-chloe-redoute-timonnier/
LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux
CATEGORIES:Meetings,Scientific seminars,Thesis defenses
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2025/09/soutenance-de-these-chloe-redoute-timonnier.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20251002
DTEND;VALUE=DATE:20251003
DTSTAMP:20250929T095807Z
CREATED:20250618T071507Z
LAST-MODIFIED:20250929T095807Z
UID:49605-1759363200-1759449599@www.bricbordeaux.com
SUMMARY:BRIC'Innov 2025
DESCRIPTION:BRIC’Innov \nBRIC Oncology Innovation Day \nThursday\, October 02\, 2025 \n\nBordeaux Biologie Santé (BBS) building\, \nCampus Carreire\, 2 rue Dr Hoffmann Martinot\, Bordeaux \n\n \n\n\n\nL’Institut de Recherche en Oncologie de Bordeaux (BRIC) is organizing\,\ntogether with its innovation partners\,\nthe first day dedicated to companies \nProgram to downloadVICTIM OF ITS OWN SUCCESS  \nREGISTRATION IS NOW CLOSED!\nIf you are already registered\, you can still access your account by logging in. \n\n\n\n\nRegistration\n(free but mandatory) PROGRAM  \n\n  \n\nFrom 8:30 a.m.: Welcome coffee and pastries \n\n\n 9 a.m. – 1 p.m.: Plenary lectures  \n\n9:00 a.m.: Opening speech: Oncology\, Research\, and Innovation in the Nouvelle-Aquitaine Region\nEtienne Duguet\, Vice President of Innovation\, University of Bordeaux;\nRichard Salives\, Regional Delegate\, Inserm;\nPhilippe Nauche\, Vice President in charge of Health and the Silver Economy\, Nouvelle-Aquitaine Region;\nEric Papon or his representative\, Regional Academic Delegate for Research and Innovation.\n\n  \n\n9:30 a.m.: Presentation of the Bordeaux Institute of Oncology\nModerator: Charlotte Cosin\, Head of Innovation\, University of Bordeaux.✔ A multidisciplinary laboratory. Frédéric Saltel\, Director of BRIC\n✔ A translational research laboratory.\nChristelle Liard\, PhD\, Head of translational cancer researchat Bordeaux University Hospital;\nMonica Arnedos\, Specialist practitioner at CLCC\, Bergonié Institute   \n\n\n10:20 am : Innovatives technologies to accelerate oncology research\nModerator : David Boucard\, Director\, ALLIS-NA.\n✔ Presentation of TBMCore technology platforms : Béatrice Turcq\, Director\n✔ I.Care Bordeaux program : Jean-Christophe Bernhard\, Coordinator.  \n\n  \nBREAK (11:00 a.m. – 11:20 a.m.) \n  \n\n11:20 a.m.: BRIC projects and innovation dynamics\nModerator : Lorena Delgado-Zabalza\, Head of Health Innovation\, University of Bordeaux..\n✔ Cible Slit2 project : Enhancing immunotherapies in the treatment of brain cancers. Thomas Mathivet\, CR\, Team 1 BRIC\n✔ Revalis Project: Convertases and protein maturation for new therapies in immuno-oncology\, A. Majid Khatib\, PhD\, Team 2 BRIC\n✔ CRISPR-Cas patent: From diagnosis to gene therapy. Sandrine Dabernat\, PU-PH & Aurélie Bedel\, PU-PH\, Team 8 (BioGO) BRIC\n \n\n12:00 p.m.: From the laboratory to the start-up\, a collective adventure involving local innovation stakeholders\nModerator: Sophie Hervé\, Health Sector Affairs Officer\, University of Bordeaux\nHadrien Mary\, Co-founder – Beliver\nLaura Bergeon\, Business developper – SATT AST\nLucia Robert\, CEO – MATWIN\nClémence Roy\, Start-up Manager – UNITEC  \nDavid Boucard\, Director – ALLIS-NA\n\n  \n  \n\n12:30 p.m.: Funding academic-private collaborations\n Moderator : Damien Louessard\, Head of Ecosystem Department\, University of Bordeaux\nMagali Pages\, Head of European Innovation\, ADI Nouvelle-Aquitaine.\nAlice Recalde\, European Projects Engineer (assembly)\, University of Bordeaux.\nMarina Galicki\, Project Manager for Innovation and Health/Chemistry/Materials – Regional Economic Department\, DREETS.\nYves Ducq\, Deputy Regional Academic Delegate for Research and Innovation.\nMarianne Lamour\, Project Manager\, Higher Education\, Research\, and Technology Transfer Department\, Nouvelle-Aquitaine Region.\nLucie Teixeira-Marinho\, Deputy Director\, Innovation\, Industry\, and Attractiveness\, Nouvelle-Aquitaine Region.\n\n\n\n  \n\n 1:00 p.m. – 2:00 p.m.: Lunch and networking  \n  \n\n 2:00 p.m. – 4:00 p.m. : MEET MY PARTNER* \n  \n⏳The B2B meetings are closed! Opportunity for informal meetings in dedicated areas on the day \n🔎 Need help? Contact : bric-innov-2025@sciencesconf.org  \n  \n\n\n\n\nPractical information \n  \n🚘Apart from the parking spaces reserved for university staff (badge required)\, you will find spaces closer by on the sidewalk along the wall on Rue du Dr Hoffmann Martinot. Otherwise\, there is a parking lot reserved for visitors a 5-minute walk away\, located at 125 Bethmann Street. \n🚊Take tram A to the Saint Augustin stop\, then follow the “cycles et piétons” (cycles and pedestrians) markings on the ground across the CHU campus. \n🚍Several bus lines nearby\, see location map \nlocation map \n\n\n\nRegistration\n(free but mandatory) \n\n#Synergies #fFinancements #SuccessStory #Networking #PlateformesTechnologiques #RencontresChercheurs\n \n\nIn partnership with:\n\nContact et informations : bric-innov-2025@sciencesconf.org \n*
URL:https://www.bricbordeaux.com/en/event/bricinnov-2025/
LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux
CATEGORIES:Meetings
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2025/06/affiche-bricinnov-2.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250929T140000
DTEND;TZID=Europe/Paris:20250929T170000
DTSTAMP:20250918T132717Z
CREATED:20250808T100416Z
LAST-MODIFIED:20250918T132717Z
UID:49855-1759154400-1759165200@www.bricbordeaux.com
SUMMARY:Thesis defense by Florian ROBERT
DESCRIPTION:Thesis defense in computer science \nFlorian ROBERT\, team 06 – MIRCADE\, Methods and Innovations for the Research in Pediatric Cancers. \nCo-supervision of thesis: Christophe Grosset (BRIC) and Baudouin Denis de Senneville (IMB- Institut des Mathématiques de Bordeaux) \nMonday\, September 29\, 2 p.m. \n“Exploration de l’organisation interne des tissus tumoraux par imagerie volumétrique\, méthodes numériques et apprentissage profond.” \nSalle des Actes bâtiment A33 campus Sciences et Technologies à Talence \nAbstract: \nUnderstanding the internal organization of tumor tissues is essential for improving cancer treatment in children. This thesis focuses on hepatoblastoma\, the most common malignant liver tumor in children. Based on 3D electron microscopy images\, a digital twin of the tumor tissue was created using innovative tools to automatically segment and identify biological structures such as cells\, nuclei or blood capillaries. This information was then used to analyze the internal organization of the tissue using unsupervised learning methods. This work opens the way to a better understanding of tumor architecture\, and ultimately aims to improve diagnosis\, choose the best treatment and better care for children with cancer.     \n  \nJury members: \nMs Karin PERNET GALLAY\, Research Engineer\, University of Grenoble Alpes\, Rapporteur\nM. Charles KERVRANN\, Directeur de Recherche\, Université de Rennes\, Rapporteur\nMrs. Nataliya SOKOLOVSKA\, Professor\, Sorbonne University\, Examiner\nMs Christèle ETCHEGARAY\, Research Fellow\, University of Bordeaux\, Examiner\nM. Baudouin DENIS DE SENNEVILLE\, Directeur de Recherche\, Université de Bordeaux\, Directeur\nM. Christophe F. GROSSET\, Directeur de Recherche\, Université de Bordeaux\, Co-Directeur
URL:https://www.bricbordeaux.com/en/event/thesis-defense-by-florian-robert/
LOCATION:salle des Actes bâtiment A33 campus Sciences et Technologies\, Talence
CATEGORIES:Meetings,Scientific seminars,Thesis defenses
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2025/08/soutenance-de-these-florian-robert.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20250925
DTEND;VALUE=DATE:20250927
DTSTAMP:20250602T104611Z
CREATED:20250602T104611Z
LAST-MODIFIED:20250602T104611Z
UID:49525-1758758400-1758931199@www.bricbordeaux.com
SUMMARY:Symposium “Microenvironment and Immunotherapy of Sarcomas”
DESCRIPTION:The BRIC is pleased to share the announcement of the 3rd International Symposium on Sarcomas\, organized as part of the RHU CONDOR program\, to be held on September 25–26\, 2025\, in Bordeaux. \nThis year’s symposium\, titled “Microenvironment and Immunotherapy of Sarcomas”\, will bring together international researchers\, clinicians\, and experts to address key challenges in the study of connective tissue tumors. Special focus will be placed on immunotherapy and the tumor microenvironment — two central pillars of current therapeutic strategies.  \nThe event is organized by the CONDOR program\, a national Hospital-University Research (RHU) project led by Antoine Italiano\, oncology researcher\, clinical oncologist\, and head of Team 9 “SarcoTarget” at the BRIC. His team\, in collaboration with Institut Bergonié\, specializes in developing new therapeutic approaches for sarcomas\, which are rare and complex cancers.  \nThis symposium will be a unique opportunity to highlight the latest scientific breakthroughs and strengthen collaboration within the global sarcoma research community. \n\n\nRegistration deadline: September 11\, 2025 \n\n\nRegistration and full program: https://condorprogram.com/symposium-3rd-edition \n\n\n\n\nWe strongly encourage you to register early to take part in these two days of rich scientific and clinical exchange.
URL:https://www.bricbordeaux.com/en/event/symposium-microenvironment-and-immunotherapy-of-sarcomas/
LOCATION:Agora du Haut Carré – Université de Bordeaux\, 43 rue Pierre Noailles\, Talence\, France
CATEGORIES:Meetings,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2025/06/design-sans-titre.jpg
ORGANIZER;CN="RHU Condor":MAILTO:contact@condorprogram.com
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250924T140000
DTEND;TZID=Europe/Paris:20250924T170000
DTSTAMP:20250918T151552Z
CREATED:20250918T151552Z
LAST-MODIFIED:20250918T151552Z
UID:50028-1758722400-1758733200@www.bricbordeaux.com
SUMMARY:HDR thesis defense by Delphine Fessart
DESCRIPTION:Delphine Fessart\, team 2.2 Oncology & Gynecology Laboratory (OncoGyne)\, will defend her Habilitation à Diriger des Recherches (HDR) on Wednesday\, September 24\, at 2:00 p.m.\, in the Conference Room (R+7) of the Bergonié Institute. \nTitle : « Décrypter les mécanismes moléculaires conduisant au développement tumoral ».
URL:https://www.bricbordeaux.com/en/event/hdr-thesis-defense-by-delphine-fessart/
LOCATION:Institut Bergonié\, 229 Cours de l'Argonne\, Bordeaux\, 33076\, France
CATEGORIES:Meetings,Scientific seminars,Thesis defenses
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2025/09/soutenance-hdr-delphine-fessart.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250923T133000
DTEND;TZID=Europe/Paris:20250923T170000
DTSTAMP:20250918T145053Z
CREATED:20250918T143354Z
LAST-MODIFIED:20250918T145053Z
UID:50017-1758634200-1758646800@www.bricbordeaux.com
SUMMARY:Thesis defense by Ruxue JIA
DESCRIPTION:Ruxue JIA will publicly defend her doctoral thesis in Cancer Biology\, supervised by Armelle MENARD\, Team 4: Digestive cancers associated with Helicobacter infection\, cancer stem cells\, and therapeutic strategies. \nTitle : Etude des voies de signalisation cellulaire modulées par les génotoxines bactériennes \nDefense scheduled for Tuesday\, September 23\, 2025\, at 1:30 p.m.\nAmphi 7\, Université de Bordeaux\, Campus Carreire\, 146 rue Leo Saignat 33000 Bordeaux \nNotice of defense with abstract available at this link (error in the notice)
URL:https://www.bricbordeaux.com/en/event/thesis-defense-by-ruxue-jia/
LOCATION:salles Nord et Sud – RDC Bâtimenet Bordeaux Biologie Santé (BBS)\, 2 rue du Dr Hoffmann Martinot\, Bordeaux\, France
CATEGORIES:Meetings,Scientific seminars,Thesis defenses
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2025/09/soutenance-de-these-ruxue-jia-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20250922
DTEND;VALUE=DATE:20251011
DTSTAMP:20250918T160613Z
CREATED:20250522T104742Z
LAST-MODIFIED:20250918T160613Z
UID:49403-1758499200-1760140799@www.bricbordeaux.com
SUMMARY:Cancer Neuroscience School - Bordeaux - 09/22 to 10/02
DESCRIPTION:Antonio C. Pagano Zottola\, Junior Professor Team 1 – Tumor and Vascular Biology Laboratory of our unit is co-organizing a Cancer Neuroscience School in Bordeaux from September 22 to October 10\, 2025. with Anna Golebiewska\, Luxembourg Institute of Health et Varun Venkataramani\, German Cancer Research Center. \n  \nThis 3-week training course is aimed at scientists at Master 2 level and above. \n  \nProgram of seminars open to the scientific community \n  \nThe Bordeaux Neuroscience School is part of Bordeaux Neurocampus\, the neuroscience department of the University of Bordeaux. The school operates on the principle that training in neuroscience and oncology research involves hands-on experimentation in a real research laboratory. A number of renowned speakers in neuro-oncology will be taking part in the course.  \nWhat to expect? \n\nHands-on projects using cutting-edge technologies from neuroscience and oncology\,\nLectures by top scientists and a Brain Prize 2025 : Frank Winkler\,\nTechniques ranging from primary cultures and organoids to advanced imaging\,\nA collaborative\, interdisciplinary environment to boost your research skills.\n\n  \nFull details and registration \n  \nDeadline Extended: Apply by July 7th
URL:https://www.bricbordeaux.com/en/event/cancer-neuroscience-school-bordeaux-09-22-to-10-02/
CATEGORIES:Meetings,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2025/05/cajal-school-cancer-neuroscience-2025-0910-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250918T080000
DTEND;TZID=Europe/Paris:20250918T120000
DTSTAMP:20250811T161757Z
CREATED:20250731T100014Z
LAST-MODIFIED:20250811T161757Z
UID:49856-1758182400-1758196800@www.bricbordeaux.com
SUMMARY:SBM Department Scientific Platforms Exhibition
DESCRIPTION:The SBM Department invites you to a special half-day event on Thursday\, September 18\, from 9 a.m. to 12 p.m.\, dedicated to scientific and technical platforms. This half-day event aims to raise awareness of the platforms’ activities and promote exchanges between doctoral students\, ITA/BIATSS\, scientists\, and any other interested staff. \nThe Platform exhibition will take place on the forecourt and/or in the lobby of the BBS (2 rue du Dr Hoffmann Martinot\, Bordeaux)\, depending on weather conditions. The programme includes : \n\nStands hosted by platform managers\nInteractive discussions and presentations\nA snack to share a convivial moment\n\nHow to participate? \n\nVisitors can simply come and explore the various stands at their own pace.\n\nFind all 18 platforms at this link. \n👉 Among them\, here are the platforms with a particular link to our BRIC unit: \n\nAquiDerm\nAquiDerm is the technology transfer structure of the team 05 – Translational Research In Oncodermatology and Orphan skin diseases (TRIO2)\, led by Hamid-Reza Rezvani and Marie Beylot-Barry\nOne of the platform’s scientific managers is Hamid-Reza Rezvani – with Julien Seneschal(ImmunoConcEpT)\, the co-managers are Jérôme Rambert and Muriel Cario\, and the scientific expert is Alain Taieb.\nIt is administratively attached to ADERA.\nCellOxia\nThe CellOxia hypoxia culture platform was created by Team 10 – Normal and Leukemic Hematopoietic Stem Cells\, led by Jean-Max Pasquet.\nThe scientific manager of the platform is Jean-Max Pasquet. The technical manager of the platform is Arnaud Villacreces.\nCrisp’edit\nThe CRISP’edit platform was created by Team 11 – Modeling Mechanisms of Transformation and Resistance in Leukemia\, led by Catherine Sawai.\nThe scientific manager of the core facility is Béatrice Turcq The technical manager of the platform is Valérie Prouzet-Mauleon.\nHistopath\nThe Histopathology core facility was created by Team 03 – Liver Cancers and Tumor Invasion\, led by Violaine Moreau and Frederic Saltel. Pierre Dubus (team 4)\, Brigitte Le bail (team 3)\, and Béatrice Turcq (team 11) are members of the Scientific Committee The technical manager of the core facility is Nathalie Dugot-Senant.\nOncoProt\nThe proteomic analysis core facility\, OncoProt\, was created by Team 03 – Liver Cancers and Tumor Invasion\, led by Violaine Moreau and Frederic Saltel\nThe scientific manager of the platform is Frederic Saltel\, and the technical manager is Anne-Aurélie Raymond.\nVect’UB\nThe vectorology platform\, Vect’UB\, was created by Team 08 – Genetic Biotherapies and Oncology (BioGO)\, led by Sandrine Dabernat and François Moreau-Gaudry. The scientific manager of the platform is François Moreau-Gaudry.\nThe technical manager of the platform is Véronique Guyonnet-Dupérat.\nVivOptic\nThe Vivoptic platform was created by the IMOTION team\, which joined Team 04 – Digestive cancers associated with Helicobacter infection\, cancer stem cells\, and therapeutic strategies\, led by Christine Varon. Christine Varon is a member of the scientific committee. The technical manager is Coralie Genevois.\nXenofish\nThe Xenofish platform was created by team 02 – Reprogramming of tumor activity and the associated microenvironment (Rytme)\, headed by A. Majid Khatib. The scientific manager of the platform is Géraldine Siegfried. The technical managers are Sandrine Fedou and Élodie Muzotte. The zootechnicians are Isabelle Auguste and Wendy Comandatore.\n\n 
URL:https://www.bricbordeaux.com/en/event/sbm-department-scientific-platforms-exhibition/
LOCATION:accueil Bâtiment BBS – Bordeaux Bioloie Santé\, 2 rue du Dr Hoffmann Martinot\, Bordeaux\, France
CATEGORIES:Meetings
ATTACH;FMTTYPE=image/png:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2025/07/banniere-salonplateformes-37888b48d43df7f650a6adeac73e407e.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250909T110000
DTEND;TZID=Europe/Paris:20250909T120000
DTSTAMP:20250711T151927Z
CREATED:20250711T151927Z
LAST-MODIFIED:20250711T151927Z
UID:49733-1757415600-1757419200@www.bricbordeaux.com
SUMMARY:Invited seminar Gautier Follain - 09-09-2025
DESCRIPTION:The BRIC unit welcomes Gautier Follain for a seminar open to the scientific community. \n  \nGautier Follain\, PhD \nShared postdoctoral researcher between the laboratories of Pr. Johanna Ivaska (University of Turku) Dr. Guillaume Jacquemet (Åbo akademi)\, both located in Turku (Finland). \nDocent at the University of Turku\, Field of application: Biophysics of cancer. \n  \nDissecting the intravascular adhesion and extravasation of Pancreatic Ductal AdenoCarcinoma. \n📆 Tuesday\, September 9 11 a.m. \n📌 BBS conference room\, 2 rue Dr Hoffmann Martinot\, Bordeaux \n  \nAbstract. \nSolid tumor progression is a complex succession of events happening in different spaces and times in the body\, ultimately leading to the formation of life-threatening metastases. To colonize distant organs\, cancer cells are exploiting the circulatory networks as natural paths before stopping in small vessels and crossing the endothelial barrier. \nMy current research focuses on the steps of intravascular adhesion and extravasation (crossing of the vessel border) of pancreatic ductal adenocarcinoma (PDAC) cell lines. My main objectives are to decipher the mechanisms allowing the cells to break the endothelial barrier\, in an attempt to identify key factors and actors during the process. I work with microfluidic models to better reproduce the physiologic conditions of perfused vessels\, zebrafish embryos which are transparent and very rapidly develop a complex vascular system and murine models. All three are coupled with quantitative and high-resolution live imaging and to single cell characterization approaches (scRNAseq\,mass cytometry\,…). \nMy ongoing results support the idea that heterogeneity of cancer\, even among laboratory cell lines\, is driving different adhesion/extravasation routes that are dramatically understudied. My talk will give an overview of my postdoc projects. 1. FlowVision\, our deep-learning based image analysis framework\, allowing the dissection of the arrest to stabilisation of circulating PDAC and immune cells (Follain et al. BioRxiv 2024). 2. An unbiased enrichment-based screening for key actors of the intravascular adhesion step. 3. The discovery of a novel extravasation route used by PDAC cells. \n  \nBio. \nI did a PhD in life science in the lab. of Dr. Jacky Goetz (Strasbourg). I studied the role of blood flow forces on arrest\, adhesion and extravasation of circulating breast/mammary cells\, using multiple imaging modalities\, mostly applied to microfluidics and zebrafish embryos. I described endothelial remodeling around arrested tumor cells as an extravasation mechanism of cancer cells (Follain et al. Dev cell 2018). Our works demonstrated that not only size exclusion but also shear forces are biophysic parameters driving the metastatic spreading (Follain et al. NRC 2020).\nI moved to Turku as a shared postdoc between the well established Cell adhesion lab of J. Ivaska\, expert in integrin biology\, and the newly born lab of G. Jacquemet focusing on cellular protrusion and cell migration. I used similar models to study the metastatic cascade of pancreatic ductal adenocarcinoma. I added to my skill set deep-learning based image analysis (Follain et al. BioRxiv 2024)\, imaging techniques\, murine models and more. \nI am now looking for the next step of my career in France..!
URL:https://www.bricbordeaux.com/en/event/invited-seminar-gautier-follain-09-09-2025/
LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux
CATEGORIES:Meetings,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2025/07/gautier-follain-2025-09-09.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20250901
DTEND;VALUE=DATE:20251001
DTSTAMP:20250814T125719Z
CREATED:20250814T124605Z
LAST-MODIFIED:20250814T125719Z
UID:49882-1756684800-1759276799@www.bricbordeaux.com
SUMMARY:Gynecological Cancer Awareness Month - Turquoise September
DESCRIPTION:As part of Septembre Turquoise\, Gynecological Cancer Awareness Month\, members of the 2.2 Oncology\, Gynecology\, and Proteostasis (OncoGyne) team led by Frederic Delom are participating in events organized by the Bergonié Institute. \n📅 From Monday\, September 1 to Tuesday\, September 30.\nProgram offered by the IMAGYN association\, a meeting and information space with the involvement of professionals from the Bergonié Institute. \n  \nProgram \n  \nMore information to come
URL:https://www.bricbordeaux.com/en/event/gynecological-cancer-awareness-month-turquoise-september/
LOCATION:Institut Bergonié\, 229 Cours de l'Argonne\, Bordeaux\, 33076\, France
CATEGORIES:Meetings
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2025/08/septembre-turquoise-bergonie-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20250708
DTEND;VALUE=DATE:20250712
DTSTAMP:20250605T085034Z
CREATED:20250605T085034Z
LAST-MODIFIED:20250605T085034Z
UID:49524-1751932800-1752278399@www.bricbordeaux.com
SUMMARY:JOBIM 2025 – Open Days in Biology\, Informatics\, and Mathematics
DESCRIPTION:From July 8 to 11\, 2025\, Bordeaux will host the 2025 edition of JOBIM (Journées Ouvertes en Biologie\, Informatique et Mathématiques) — a major event for the French-speaking bioinformatics community. This year’s conference will take place at LaBRI (Bordeaux Computer Science Research Laboratory)\, bringing together researchers\, engineers\, PhD students\, and professionals from both digital and life sciences to explore the latest developments in the field.  \nThrough the ODIL unit (Omics Data Integration & visuaLization)\, BRIC’s internal bioinformatics cell\, two of our members are currently part of the event’s organizing committee: \n\nCyril Dourthe\, bioinformatics research engineer (BRIC and OncoProt platform)\nÉlodie Darbo\, research engineer in Team 7 – Targeting Transcription in Breast Cancer\n\nTheir involvement reflects the growing role of bioinformatics in oncology research\, particularly in the work carried out within our laboratory\, where the analysis of large-scale data from RNA-seq\, epigenomics\, and cell modeling has become an essential foundation. \nHeld at the crossroads of biology\, mathematics\, and computer science\, the JOBIM conference offers a rich program of talks\, workshops\, roundtables\, and networking opportunities. The 2025 edition promises excellent visibility for research conducted in our region and for all stakeholders driving innovation in health.  \n\nProgram & registration: https://jobim2025.labri.fr\n\nRegistration open from May 15 to June 15\, 2025
URL:https://www.bricbordeaux.com/en/event/jobim-2025-open-days-in-biology-informatics-and-mathematics/
LOCATION:LaBRI
CATEGORIES:Meetings
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2025/06/gclv2l9wiaaw6oe-scaled.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250704T110000
DTEND;TZID=Europe/Paris:20250704T120000
DTSTAMP:20250522T081608Z
CREATED:20250522T081608Z
LAST-MODIFIED:20250522T081608Z
UID:49391-1751626800-1751630400@www.bricbordeaux.com
SUMMARY:Invited seminar - Adriano Sabino - 04-07-2025
DESCRIPTION:Pr Adriano Sabino is invited by Vanessa Desplat\, Team 10\, Normal and Leukemic Hematopoietic Stem Cells. \nTitle: Omics Sciences Applied to the Investigation of Potential Biomarkers and Therapeutic Targets in Acute Leukemias \nPresenter: Prof. Adriano de Paula Sabino – Federal University of Minas Gerais (UFMG)\, Brazil  \nBio: Associate Professor at the Federal University of Minas Gerais (UFMG)\, Brazil. Holds a Ph.D. in Pharmaceutical Sciences with postdoctoral training in cancer therapy resistance at Michigan State University. Academic and research expertise in Clinical\, Experimental\, and Molecular Hematology. Research interests encompass cancer biology\, acute and chronic leukemias\, chemotherapy resistance\, molecular and cellular biomarkers\, functional genomics\, proteomics\, metabolomics\, nanobiomaterials\, regenerative medicine\, cell-based therapies\, and the application of bioinformatics to precision medicine.     \nAbstract: \nAcute leukemias\, including Acute Lymphoblastic Leukemia (ALL) and Acute Myeloid Leukemia (AML)\, are aggressive hematologic malignancies with high biological heterogeneity and limited predictive tools for therapeutic response and disease progression. In this context\, omics sciences offer powerful strategies to unravel the molecular complexity underlying these diseases and support the identification of new biomarkers and therapeutic targets.  \nThis seminar will provide an overview of our translational research efforts combining metabolomics\, clinical peptidomics\, and machine learning. We will discuss the conceptual and methodological foundations for applying mass spectrometry-based omics approaches (LC-MS and MALDI-TOF/MS) to plasma samples\, as well as the integration of artificial intelligence algorithms to enhance biomarker discovery\, risk stratification\, and individualized therapeutic guidance.  \nAdditionally\, we present the rationale and design of predictive modeling studies employing clinical and genomic datasets from AML patients. These models\, based on supervised learning techniques\, aim to improve the accuracy of outcome prediction and inform precision oncology strategies.  \nOur interdisciplinary approach highlights the potential of integrating systems biology\, data science\, and clinical research to advance personalized medicine in oncohematology. \nKeywords: Acute leukemia\, ALL\, AML\, biomarkers\, omics sciences\, LC-MS\, MALDI-TOF/MS\, machine learning\, precision oncology\, clinical stratification. \n📆 Friday 04-07\, 11am \n📌 BBS conference room\, 2 rue Dr Hoffmann Martinot Bordeaux
URL:https://www.bricbordeaux.com/en/event/invited-seminar-adriano-sabino-04-07-2025/
LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux
CATEGORIES:Meetings,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2025/05/seminar-adriano-sabino-2025-07-13.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250702T100000
DTEND;TZID=Europe/Paris:20250702T130000
DTSTAMP:20250627T075338Z
CREATED:20250602T095142Z
LAST-MODIFIED:20250627T075338Z
UID:49523-1751450400-1751461200@www.bricbordeaux.com
SUMMARY:HDR Defense – Thomas MATHIVET
DESCRIPTION:HDR Defense (Accreditation to Supervise Research) in Life and Health Sciences \nThomas Mathivet Team 01 – Tumor and Vascular Biology Laboratory \n“Les molécules de guidage : de l’angiogenèse à la dynamique stromale et à l’invasion des tumeurs cérébrales” \nWednesday\, July 2\, 2025 at 10:00 AM \nBBS Amphitheater\, 2 rue Dr H. Martinot\, Bordeaux (Carreire Campus) \nJury \n➢ M Eric CHEVET\, Directeur de recherche\, Biosit\, INSERM – Rapporteur\n➢ Mme Barbara GARMY-SUSINI\, Directrice de recherche\, I2MC\, INSERM – Rapporteure\n➢ Mme Anna-Rita CANTELMO\, Chargée de recherche\, Université de Lille – Rapporteure\n➢ M François MOISAN\, Docteur\, Université de Bordeaux – Examinateur\n➢ M Andreas BIKALVI\, Professeur des universités\, Université de Bordeaux – Examinateur
URL:https://www.bricbordeaux.com/en/event/hdr-defense-thomas-mathivet/
LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux
CATEGORIES:Meetings,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2025/06/soutenance-hdr-thomas-mathivet-1.jpg
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END:VCALENDAR