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X-WR-CALDESC:Events for Bordeaux Institute of Oncology
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DTSTART;TZID=Europe/Paris:20220615T120000
DTEND;TZID=Europe/Paris:20220615T130000
DTSTAMP:20220616T104628Z
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SUMMARY:Interdisciplinary seminar Oncosphère - Charles Dupin et Julian Boutin
DESCRIPTION:Charles Dupin and Julian Boutin\, Team 08 – Genetic Biotherapies and Oncology (BioGO) will be speaking on June 15 at 12:00 p.m. as part of Oncosphere‘s interdisciplinary seminars via videoconference. \nVideo conferencing link. \n  \n Charles Dupin\, PH \n  Radiothérapie potentialisée par un précurseur de l’hème dans le glioblastome. \nLa radiothérapie est un traitement indispensable du glioblastome\, tumeur cérébrale primitive. Les chirurgiens utilisent depuis une vingtaine d’années un précurseur de l’hème pour visualiser la tumeur en per opératoire. Son accumulation spécifique dans le glioblastome pourrait être utilisée pour sensibiliser la radiothérapie. \nNous avons exploré cette question de la radiosensibilisation in vitro sur des cellules dérivés de patients s’auto-organisant en sphéroïdes. Pour aller plus loin\, des souris imunodéprimées\, implantées en intracérébral ont été irradiées. L’efficacité de ce précurseur de l’hème pour radiosensibiliser a été testé. \n  \n Julian Boutin\, PHU \nThérapie génique anti-cancer par CRISPR-Cas9. \nLa technologie CRISPR-Cas9 permet une très grande efficacité d’édition génique. Ce système pourrait constituer une nouvelle arme anti-cancer très efficace. Des résultats très prometteurs ont été obtenus dans des approches ex vivo pour modifier des lymphocytes (CAR T cells). Nous proposons d’utiliser cette technologie pour modifier le métabolisme tumoral de la biosynthèse de l’hème dans le modèle du cancer de la prostate. Le but est de proposer une alternative thérapeutique innovante: potentialiser les effets de la photothérapie dynamique en l’associant à une thérapie génique.
URL:https://www.bricbordeaux.com/en/event/interdisciplinary-seminar-oncosphere-charles-dupin-et-julian-boutin/
LOCATION:visio
CATEGORIES:Meetings,News,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2022/06/seminaire-oncosphere-15-juin.jpg
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20220617
DTEND;VALUE=DATE:20220618
DTSTAMP:20220721T101432Z
CREATED:20220721T101432Z
LAST-MODIFIED:20220721T101432Z
UID:20293-1655424000-1655510399@www.bricbordeaux.com
SUMMARY:Donation of Noéline’s parents to the MIRCADE team for the research on diffuse intrinsic pontine glioma (DIPG)
DESCRIPTION:The association “Noeline\, my daughter\, my battle” was created to raise funds to allow Noeline\, 9 years old\, diagnosed with a diffuse intrinsic pontine glioma (DIPG)\, to follow an innovative treatment in clinical trial in the United States. Unfortunately\, Noeline passed away on March 22\, 2022\, 8 months after her diagnosis. As Noeline could not benefit from this treatment\, her parents decided to donate the funds collected to GITC research. Thus\, on June 17\, 2022\, theteam 06 – MIRCADE (Methods and Innovations for Research on Childhood Cancers)\, led by Christophe Grosset received a check for nearly 21 000 € from the association. This donation will be used to finance expenses related to the project of Guillaume Herrault\, a PhD student\, who started his thesis under the supervision of Christophe Grosset in October 2021 after 5 months as a Master 2 student. \nRead the article published in the Dauphiné Libéré on July 2 : https://www.ledauphine.com/sante/2022/07/02/isere-le-pont-de-claix-noeline-une-cagnotte-au-profit-de-la-recherche-contre-le-cancer \nThe Facebook page of the association Noéline\, ma fille\, ma bataille : https://www.facebook.com/No%C3%A9line-ma-fille-ma-bataille-100170252409146
URL:https://www.bricbordeaux.com/en/event/donation-of-noelines-parents-to-the-mircade-team-for-the-research-on-diffuse-intrinsic-pontine-glioma-dipg/
CATEGORIES:News
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2022/07/donation-noeline-mircade.jpg
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20220617T133000
DTEND;TZID=Europe/Paris:20220617T140000
DTSTAMP:20220616T103704Z
CREATED:20220616T103647Z
LAST-MODIFIED:20220616T103704Z
UID:19928-1655472600-1655474400@www.bricbordeaux.com
SUMMARY:Techno presentation: CYTENA - CELLCYTE X presentation - Full live cell imaging solution
DESCRIPTION:Presentation organized by the BRIC technology group. \npdf document to consult : CELLCYTE X Features & Benefits \nCYTENA – CELLCYTE X presentation – Full live cell imaging solution. \n\nJim Engström\, Field Application Specialist\nJulia Cantarini\, Technical Sales Specialist – Live Cell Analysis – Central Europe\n\nBy videoconference zoom : ID de réunion : 895 4582 4767
URL:https://www.bricbordeaux.com/en/event/techno-presentation-cytena-cellcyte-x-presentation-full-live-cell-imaging-solution/
LOCATION:visio
CATEGORIES:Meetings,News,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2022/06/cytena.jpg
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20220621T140000
DTEND;TZID=Europe/Paris:20220621T150000
DTSTAMP:20220623T083317Z
CREATED:20220616T103519Z
LAST-MODIFIED:20220623T083317Z
UID:19927-1655820000-1655823600@www.bricbordeaux.com
SUMMARY:SBM Department Seminar: Andreas Bikfalvi
DESCRIPTION:Andreas Bikfalvi\, Head of Team 01 – Tumor and Vascular Biology Laboratory. \n“The notion of Truth in the Biomedical Sciences” \nThe notion of truth has been debated extensively by philosophers and scientists alike for centuries. Relativist and absolutist/objectivist philosophies have a complete different understanding of the value attached to this notion. In this presentation\, I will discuss a number of issues related to the notion of truth in the biomedical sciences. I will first lay out different meanings and forms of truth and then discuss how this relates to the notion of causality. I will then describe how the biomedical science produces “truth” and lay down the different ways to achieve this (induction\, causal inference\, falsification\, Baysian approach\, etc..). \nI will then illustrate this by citing examples from the medical history and present-day biomedical research related to infectious disease\, vascular biology and cancer research. I will then show that a strong relativist epistemology is incompatible with the way biomedical science obtains knowledge. Thus\, in my view\, a realistic notion of truth is central to achieve a sound understanding of physiology and pathology\, and for the development of therapies grounded in a correct knowledge of disease. \nJune 21 at 2 p.m.\, IBGC conference room\, Carreire. \nPhoto ©Gautier DUFAU \nThe recording is online!
URL:https://www.bricbordeaux.com/en/event/sbm-department-seminar-andreas-bikfalvi/
LOCATION:salle de conférence IBGC – Carreire\, 146 rue Leo Saignat\, Bordeaux\, 33000\, France
CATEGORIES:Meetings,News,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2022/06/photo-a.-bikfalvi-@gautier-dufau.jpg
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20220628T150000
DTEND;TZID=Europe/Paris:20220628T160000
DTSTAMP:20220622T074336Z
CREATED:20220616T102918Z
LAST-MODIFIED:20220622T074336Z
UID:19923-1656428400-1656432000@www.bricbordeaux.com
SUMMARY:SBM Department Seminar - Sabine Colnot
DESCRIPTION:Sabine Colnot\, Centre de Recherche des Cordeliers\, Paris\, will speak on June 28 at 3:00 pm\, amphitheater 11\, Carreire campus. \nInvited by Violaine Moreau\, team leader of theTeam 03 – Liver Cancers and Tumor Invasion. \n“CRISPR-Cas9-engineered mice developing liver cancers with beta-catenin mutation: towards a better understanding of liver carcinogenesis” \nOne third of hepatocellular carcinoma (HCC) have mutations activating beta-catenin signaling. We definitely showed that these mutations are oncogenic in mice (Loesch et al.\, J Hepatol 2022)\, and are responsible for the development of HCC and mesenchymal hepatoblastoma. This mouse model and a previous one obtained through a loss of function of Apc are valuable preclinical models to better understand why a large subset of beta-catenin activated HCCs are resistant to immunotherapies. Our work further supports the hypothesis that they could be treated based on their metabolism (Gougelet et al.\, Gastroenterol 2019; Senni et al.\, Gut 2019). Lastly\, the CRISPR-Cas9 strategy appears to be an easy-to-use approach to investigate the oncogenic function of specific mutations in HCC.
URL:https://www.bricbordeaux.com/en/event/sbm-department-seminar-sabine-colnot/
LOCATION:Amphithéâtre 11\, campus Carreire\, 146 rue Léo Saignat\, Bordeaux\, 33000\, France
CATEGORIES:Meetings,News,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2022/06/sabine-colnot.jpg
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