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X-ORIGINAL-URL:https://www.bricbordeaux.com/en/
X-WR-CALDESC:Events for Bordeaux Institute of Oncology
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TZID:Europe/Paris
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20231207T100000
DTEND;TZID=Europe/Paris:20231207T130000
DTSTAMP:20231120T145013Z
CREATED:20231120T145013Z
LAST-MODIFIED:20231120T145013Z
UID:45020-1701943200-1701954000@www.bricbordeaux.com
SUMMARY:Thesis defense Sergio de Hita
DESCRIPTION:Sergio de Hita\, team 08 BIOGO will present his thesis in genetics on Thursday December 7 at 10am\, amphi Denucé campus Victoire. \nTitle : MAPK modulation and its implications in KRAS mutant lung adenocarcinoma. \nThesis co-supervised by David Cappellen (BRIC\, team 8) and David Santamaria – Salamanca Cancer Research Center (CIC-IBMCC)\, Team Novel RAS regulators in cancer & homeostasis \nNotice of defense at this link
URL:https://www.bricbordeaux.com/en/event/thesis-defense-sergio-de-hita/
LOCATION:Amphi Dénucé\, Victoire\, 3ter Pl. de la Victoire\, Bordeaux\, 33000\, France
CATEGORIES:Meetings,Scientific seminars,Thesis defenses
ATTACH;FMTTYPE=image/png:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2023/11/soutennace-de-these-sergio-de-hita.png
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20231208T143000
DTEND;TZID=Europe/Paris:20231208T170000
DTSTAMP:20231121T133512Z
CREATED:20231121T090019Z
LAST-MODIFIED:20231121T133512Z
UID:45041-1702045800-1702054800@www.bricbordeaux.com
SUMMARY:Thesis defense Mélanie Moreau
DESCRIPTION:Mélanie Moreau\, team 03 – Liver Cancers and Tumor Invasion\, will present her thesis on Friday\, December 8\, 2:30 p.m. in the CGFB amphitheatre\, 146 rue Leo Saignat\, Bordeaux. \nsupervisor: Frédéric Saltel \n  \nInvolvement of invadosomes in tumor invasion through two examples\, Ruvbl2 in molecular organization and DDR2 in angiogenesis \nMetastasis is the main cause of death in cancer patients. Around 90% of all deaths are attributed to tumor invasion. Invadosomes are F-actin structures known to be involved in the metastatic process\, particularly through their function of extracellular matrix degradation. This promotes the migration of cells into the extracellular matrix\, and enables them to cross anatomical barriers such as vessel walls. In this thesis\, I focused on the role of Ruvbl2 in invadosome formation and activity. Ruvbl2 is an AAA+ATPase\, member of the R2TP complex\, which plays a chaperoning role in the formation of big protein complexes and is found enriched in rosette-shaped invadosomes. I have contributed to demonstrating that Ruvbl2 is involved in the process of invadosome formation and\, more specifically\, in the organization of these structures into rosettes\, via the R2TP complex. This complex protects several proteins involved in invadosome formation\, including Fak\, from autophagic degradation. I was also interested in the regulation of angiogenesis via invadosome formation and activity in endothelial cells. I demonstrated that\, in the presence of type I fibrillar collagen\, proteasome interacts with DDR2 receptor and negatively regulates invadosome activity. Proteasome inhibition drastically increases invadosome degradation activity. This inhibition stimulates DDR2 activation\, mainly by Src. These results underline the importance of a balance between Src and proteasome activity to avoid cell death. Finally\, this work provides a better understanding of mechanisms of induction\, formation and regulation of invadosomes. It highlights a set of proteins and functions linked to these invasive structures that could be pharmacologically targeted to inhibit metastasis.     \n  \nKey words : Cancer – Invadosomes – Invasion – Ruvbl2 – R2TP – DDR2
URL:https://www.bricbordeaux.com/en/event/thesis-defense-melanie-moreau/
LOCATION:salle de conférence CGFB – site Carreire\, 146 rue Leo Saignat\, Bordeaux\, 33000\, France
CATEGORIES:Meetings,Scientific seminars,Thesis defenses
ATTACH;FMTTYPE=image/png:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2023/11/soutenance-de-these-melanie-moreau-1.png
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20231214T141500
DTEND;TZID=Europe/Paris:20231214T170000
DTSTAMP:20231207T155834Z
CREATED:20231207T155239Z
LAST-MODIFIED:20231207T155834Z
UID:45132-1702563300-1702573200@www.bricbordeaux.com
SUMMARY:Léa Normand thesis defense
DESCRIPTION:Léa Normand\, Team 03 – Liver Cancers and Tumor Invasion\, will submit her thesis in Cell Biology and Pathophysiology. \nThursday\, December 14\, 2:15pm\, BBS lecture hall\, 2 rue du Dr Hoffmann Martinot\, Bordeaux \nTitle : “Implication du collagène dans la dégradation\, la migration et l’invasion tumorale.” \nThesis director : Frédéric Saltel \nNotice of defense available at this link. \nTaking advantage of her presence on the thesis jury\, we invite Madame Corinne Bousquet – Centre de Recherches en Cancérologie de Toulouse (CRCT) – to give a lecture on the same day at 10:30 am. All the info at this link.
URL:https://www.bricbordeaux.com/en/event/lea-normand-thesis-defense/
LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux
CATEGORIES:Scientific seminars,Thesis defenses
ATTACH;FMTTYPE=image/png:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2023/12/soutenance-de-these-lea-normand-illustration.png
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20231215T140000
DTEND;TZID=Europe/Paris:20231215T170000
DTSTAMP:20231215T155554Z
CREATED:20231215T155554Z
LAST-MODIFIED:20231215T155554Z
UID:45219-1702648800-1702659600@www.bricbordeaux.com
SUMMARY:Camille Dantzer thesis defense
DESCRIPTION:Camille Dantzer\, team 03 – Liver Cancers and Tumor Invasion will submit its thesis in Cell Biology and Pathophysiology. \nFriday\, December 15\, 2pm BBS amphitheatre\, 2 rue du Dr Hoffmann Martinot\, Bordeaux \nTitle : « Implication des exosomes et des chimiokines dans l’évasion immunitaire des carcinomes hépatocellulaires mutés pour la ßcaténine. » \nThesis work directed by Ms. Clotilde BILLOTTET \nNotice of defense available at this link.
URL:https://www.bricbordeaux.com/en/event/camille-dantzer-thesis-defense/
CATEGORIES:Scientific seminars,Thesis defenses
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2023/12/soutenance-de-these-camille-dantzer.jpg
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20231215T150000
DTEND;TZID=Europe/Paris:20231215T170000
DTSTAMP:20231212T140750Z
CREATED:20231212T140750Z
LAST-MODIFIED:20231212T140750Z
UID:45220-1702652400-1702659600@www.bricbordeaux.com
SUMMARY:Rarahu Magaut thesis defense
DESCRIPTION:Defense of Rarahu Magaut‘s thesis in Cell Biology and Physiopathology (Team 1 – Tumor and Vascular Biology Laboratory). \nFriday 15/12\, 9 a.m. (Montreal time)\, or 3 p.m. in Bordeaux : \nZoom link on request \nGoodman Cancer Institute (salle 501)\, 1160 Avenue des Pins Ouest H3A 1A3\, Montréal\, Québec\, CANADA \nTitle : PRL2/PTP4A2\, un modulateur des fonctions lymphatiques et de l’inflammation \nThesis co-supervised by Andreas Bikfalvi (team 1) and Michel Tremblay (Goodman Cancer Institute\, McGill University\, Montreal) \nNotice of defense at this link
URL:https://www.bricbordeaux.com/en/event/rarahu-magaut-thesis-defense/
CATEGORIES:Meetings,Scientific seminars,Thesis defenses
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2023/12/soutenance-rarahu-magaut-1.jpg
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20231221T140000
DTEND;TZID=Europe/Paris:20231221T170000
DTSTAMP:20231218T134524Z
CREATED:20231218T134524Z
LAST-MODIFIED:20231218T134524Z
UID:45235-1703167200-1703178000@www.bricbordeaux.com
SUMMARY:Joudi El Mir thesis defense
DESCRIPTION:Defense of thesis in Cell Biology and Physiopathology by Joudi El Mir\, team 05 – Translational Research In Oncodermatology and Orphan skin diseases (TRIO2). \nTitle : Modélisation des Anomalies Pigmentaires chez les Patients atteints de Xeroderma Pigmentosum-C en utilisant Xenopus laevis comme modèle in vivo.\nThesis co-supervised by Hamid-Reza REZVANI (BRIC team 05) and Hussein FAYYAD-KAZAN (Lebanese university)\nDefense scheduled for Thursday\, December 21\, 2023 at 2:00 p.m. \nCGFB\, Centre de Génomique Fonctionelle Bordeaux\,\n146 Rue Léo Saignat\, 33076 Bordeaux cedex \nNotice of defense at this link
URL:https://www.bricbordeaux.com/en/event/joudi-el-mir-thesis-defense/
LOCATION:salle de conférence CGFB – site Carreire\, 146 rue Leo Saignat\, Bordeaux\, 33000\, France
CATEGORIES:Scientific seminars,Thesis defenses
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2023/12/soutenance-de-these-joudi-el-mir.jpg
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