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X-WR-CALDESC:Events for Bordeaux Institute of Oncology
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TZID:Europe/Paris
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DTSTART;TZID=Europe/Paris:20240927T140000
DTEND;TZID=Europe/Paris:20240927T170000
DTSTAMP:20240903T092948Z
CREATED:20240903T092948Z
LAST-MODIFIED:20240903T092948Z
UID:47866-1727445600-1727456400@www.bricbordeaux.com
SUMMARY:Elisabeth Lata thesis defense
DESCRIPTION:PhD specialization: Genetics \nElisabeth Lata\, Team 07 – Targeting Transcription in Breast Cancer.. \nSupervisor Martin Teichmann \nL’isoforme embryonnaire de l’ARN polymérase III humaine : son rôle dans la transformation tumorale et l’établissement de métastases. \nAmphithéâtre B Faculté d’odontologie\,\n146 rue Léo Saignat\, 33076 Bordeaux \n\nNotice of defense with abstract and jury members at this link
URL:https://www.bricbordeaux.com/en/event/elisabeth-lata-thesis-defense/
LOCATION:Amphi B\, faculté Odontologie\, 146 rue Léo Saignat\, Bordeaux\, France
CATEGORIES:Meetings,Scientific seminars,Thesis defenses
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/09/soutenance-de-these-elisabeth-lata.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240923T140000
DTEND;TZID=Europe/Paris:20240923T170000
DTSTAMP:20240902T092908Z
CREATED:20240902T092647Z
LAST-MODIFIED:20240902T092908Z
UID:47677-1727100000-1727110800@www.bricbordeaux.com
SUMMARY:Soutenance de thèse Adèle Delamarre
DESCRIPTION:Thesis defense in Cancer Biology Adèle Delamarre Team 03 – Liver Cancers and Tumor Invasion.Thesis supervisor Victor De Ledinghen Monday\, September 23 – 2pm BBS Amphi 2 rue Dr H. Martinot – Bordeaux (Carreire) “Metabolic steatopathy and hepatocellular carcinoma: prediction of carcinogenesis to treatment response by proteomic profiling.”
URL:https://www.bricbordeaux.com/en/event/soutenance-de-these-adele-delamarre/
LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux
CATEGORIES:Meetings,Scientific seminars,Thesis defenses
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/09/soutenance-de-these-adele-delamarre.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240918T140000
DTEND;TZID=Europe/Paris:20240918T170000
DTSTAMP:20240916T160531Z
CREATED:20240916T160531Z
LAST-MODIFIED:20240916T160531Z
UID:47811-1726668000-1726678800@www.bricbordeaux.com
SUMMARY:HDR defense Monica Arnedos Ballester
DESCRIPTION:HDR defense “Habilitation à Diriger la Recherche” in Life and Health Sciences \nMonica ARNEDOS BALLESTER Team 07 – Targeting Transcription in Breast Cancer. \n“La recherche translationnelle dans le cancer du sein : vers une personnalisation des traitements.” \nWednesday\, September 18\, 2024 at 2 p.m. \nLibrary/meeting room\, Institut Bergonié. 229 cr Argonne\, Bordeaux
URL:https://www.bricbordeaux.com/en/event/hdr-defense-monica-arnedos-ballester/
LOCATION:Institut Bergonié\, 229 Cours de l'Argonne\, Bordeaux\, 33076\, France
CATEGORIES:Meetings,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/09/soutenance-hdr-monica-arnedos.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240910T093000
DTEND;TZID=Europe/Paris:20240910T110000
DTSTAMP:20240908T201411Z
CREATED:20240715T110235Z
LAST-MODIFIED:20240908T201411Z
UID:47424-1725960600-1725966000@www.bricbordeaux.com
SUMMARY:Invited seminar – Pr. Tapas Kundu - 2024-09-10
DESCRIPTION:Martin Teichmann\, Team 07 – Targeting Transcription in Breast Cancer\, invites Pr. Tapas Kundu to present a seminar. \nPr Tapas Kundu \nTranscription and Disease Laboratory\, Molecular Biology and Genetics Unit\, Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) – India \n  \nChromatin meets autophagy: A tale of nonhistone chromatin protein mediated genome organization and transcription regulation \nThe eukaryotic genome is intricately organized on a beads-on-string structure into nucleoprotein filaments. These filamentous structures consist of nucleosome beads\, composed of approximately 147 base pairs of DNA and four octameric core histones. The folding pattern of these nucleosomes varies depending on the cellular state\, ensuring the overall stability and balance within the organism. In addition to DNA and histones\, various non-histone chromatin-associated proteins along with RNA molecules also play crucial roles in fine-tuning the organization and function of the genome. Our laboratory discovered that a highly abundant nuclear protein\, human transcription coactivator PC4\, is a non-histone component involved in the genome organization\, stability\, and maintenance of the epigenetic state. By employing atomic force and electron microscopy\, we have demonstrated that PC4 directly interacts with core histones and linker histone H1 thus compacting the genome very efficiently. Our experimental results obtained from ATAC-Seq and RNA-Seq analysis provide valuable insights into the regulatory role of PC4 in genome organization. We observed that when PC4 is absent\, there is a significant increase in genome decompaction accompanied by hyper-acetylation levels and abnormal gene expression patterns. Interestingly\, we discovered that embryonic development was impaired in mice lacking PC4\, indicating its essential role for survival. However\, intriguingly\, cell lines with reduced levels of PC4 exhibited enhanced cell proliferation rates and demonstrated resistance to radiation exposure. Further investigation revealed that the mechanism behind this radiation resistance involves the upregulation of autophagy pathways upon depletion of PC4. Remarkably\, our ATAC-Seq data unveiled pervasive genomic decompaction coupled with heightened acetylation specifically at multiple loci related to autophagy-associated genes within these knockdown cells. A similar occurrence was observed in both brain and spleen-specific knockout models of PC4 in mice as well as C. elegans. However\, it is worth noting that the brain-specific knockout of PC4 did not exhibit a pronounced phenotype apart from noticeable impairments in memory extinction. Interestingly\, when PC4 was absent\, there was a significant increase in the expression level of another non-histone protein that interacts with PC4. We intend to further investigate the primary role of this complex involving PC4 in heterochromatinization and its subsequent physiological functions.              \n  \n📌 BBS conference room\, 2 rue Dr Hoffamnn Martinot – Bordeaux \n  \n📆 10/09/2024\, 9h30 \n  \nBiography \nProfessor\nSir J. C. Bose National Fellow Silver Jubilee Professor (2015-16) Transcription and Disease Laboratory Molecular Biology and Genetics Unit JNCASR\, Jakkur P.O.\, Bangalore -560064\, India Ph: 91-80-2208 2679 / 2840/ 41\, Mobile: 09449456334. Email: tapas@jncasr.ac.in \nFormer Director\nCSIR- Central Drug Research Institute\, Lucknow \nAdjunct Professor\,\nSpecial Centre for Molecular Medicine\,\nJawaharlal Nehru University\, New Delhi \nLifetime Distinguished Professor\nUniversity of Mysore\, Karnataka \nDistinguished Visiting Professor\nSDU Academy of Higher Education and Research\,\nKarnataka\, India \nDistinguished Visiting Professor\nIndian Institute of Technology\, Bombay \n  \nProf. Tapas Kumar Kundu completed his master’s degree in Biochemistry from the University of Agricultural Sciences\, Bangalore in 1989\, winning a gold medal for standing first in the master’s degree examination. He was awarded his Ph.D. from the Indian Institute of Science\, Bangalore\, in the year 1995 with the best thesis award. Following his Ph.D.\, he had a short stint as a visiting foreign research associate in the National Institute of Genetics\, Mishima\, Japan\, followed by a post-doctoral fellowship at the Rockefeller University\, USA (1996-99). He joined JNCASR as in 1999. Prof. Kundu has made significant contributions in the area of regulation of gene expression and its link to disease and therapeutics. He is not only elucidating the mechanisms of transcription regulation through the epigenetic modifications but also targeting them to design new generation diagnostics\, as well as therapeutics. Over the years\, he has published several research papers in many international journals. Several patent applications from the laboratory have been granted and some are under process\, which include several academically important research reagents with potential commercial values\, some of which have already been commercialized by renowned companies. He is a fellow of four major national academies of India and served as an editorial board member of the Journal of Biological Chemistry (JBC) from 2011-2016. Presently\, he is serving as an “Associate Editor” of the Journal of Biochemistry (Oxford University Press)\, Series Editor of Subcellular Biochemistry (Springer Nature)\, and the reviewing Editor of eLife Journal. As a Director of CSIR-CDRI\, Lucknow\, Prof. Kundu initiated many relevant academic and drug development programs. Under his leadership\, several drug molecules reached Phase-I clinical trials and could be licensed to industries for further development. He also led and completed Phase-III clinical trials for anti-Covid 19 therapy which is awaiting DCGI approval. He was instrumental to establish the ‘Asian Forum for Chromatin and Chromosome Biology and ‘Chemical Biology Society\, India’. Besides fundamental research\, Prof. Kundu is also involved in teaching and organizing science outreach programs. His popular lectures on ‘Genes\, Disease and Therapeutics’ have benefitted high school and college students greatly. \n  \nHe is the recipient of several awards\, noteworthy among which are: the Shanti Swarup Bhatnagar Prize from CSIR (2005)\, the National Academy of Science\, India- Reliance Industries Platinum Jubilee Award (2008)\, the Sir JC Bose National Fellowship from DST (2010)\, the GD Birla award for scientific research (2011)\, The Ranbaxy Research Award 2011 in the field of Medical Sciences – Basic Research and India Innovation Award 2012 given by Merck Millipore 2012 (First place)\, Shri Om Prakash Bhasin Award for the year 2019 in the field of Health  Medical Sciences by the Shri Om Prakash Bhasin Foundation\, New Delhi\, Sir M. Visvesvaraya Lifetime Achievement Award for Senior Scientists / Engineers (2021)\, and ICBS-2022 Global Lectureship Award by International Chemical Biology Society (ICBS). \n 
URL:https://www.bricbordeaux.com/en/event/invited-seminar-pr-tapas-kundu-2024-09-10/
LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux
CATEGORIES:Meetings,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/07/invited-seminar-tapas-kundu.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20240831
DTEND;VALUE=DATE:20240901
DTSTAMP:20240808T135947Z
CREATED:20240806T143657Z
LAST-MODIFIED:20240808T135947Z
UID:47571-1725062400-1725148799@www.bricbordeaux.com
SUMMARY:Alpha 1-Antitrypsin deficiency - siRNA treatments - Information meeting
DESCRIPTION:Marion Bouchecareilh\, CR CNRS team 8\, is organizing an information and exchange day for patients with Alpha 1-Antitrypsin deficiency concerning siRNA treatments for the liver damage associated with this deficiency\, on Saturday August 31\, 2024 in Bordeaux (Campus Bordeaux Pey-Berland). The aim of this event\, which will be attended by a number of French experts\, is to present and explain to patients the mode of action of siRNA treatments\, the various clinical trials currently underway and their modalities\, and feedback on this type of treatment for other pathologies. The aim of this meeting is to provide an opportunity for exchange and sharing between patients\, patient associations and the various players involved in understanding and combating the symptoms associated with this deficiency. Program available at this link Hybrid format. Free but mandatory registration before August 15 at this link  Interview with Dr Marion Bouchecareilh for FilFoie\, partner of this event\, available at this link.   \nDr Marion Bouchecareilh presents the rare disease she is studying: Alpha 1-Antitrypsin deficiency\, and the ongoing Phase 3 clinical trial involving siRNA treatment of liver damage associated with this deficiency. She also takes advantage of this interview to talk about the projects she is developing concerning primary hepatopathies and cancers of the liver associated with Alpha 1-Antitrypsin deficiency. Dr Bouchecareilh is leading the latter project in partnership with Dr Samuel Amintas\, MCU-PH also in BRIC team 8.
URL:https://www.bricbordeaux.com/en/event/alpha-1-antitrypsin-deficiency-sirna-treatments-information-meeting/
LOCATION:Pôle Juridique et judiciaire de l’Université de Bordeaux\, 35 place Pey Berland\, Bordeaux\, France
CATEGORIES:Meetings,News,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/08/journee-deficit-alpha-1-antitrypsine-.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240716T110000
DTEND;TZID=Europe/Paris:20240716T120000
DTSTAMP:20240712T103634Z
CREATED:20240704T125926Z
LAST-MODIFIED:20240712T103634Z
UID:47308-1721127600-1721131200@www.bricbordeaux.com
SUMMARY:Invited seminar - Pr. Alain Gobert - 2024-07-16
DESCRIPTION:Christine Varon\,team 04 – Helicobacter-associated digestive cancers\, cancer stem cells and therapeutic strategies \, invites Pr Alain Gobert to present a seminar. \nPr Alain Gobert\nResearch Professor of Medicine\, Division of Gastroenterology\, Hepatology and Nutrition\, Center for Mucosal Inflammation and Cancer\, Vanderbilt University Medical Center\nNashville\, TN\, USA \nRole of polyamines and electrophilic stress in gastrointestinal carcinogenesis: Therapeutic implications. \nGastric cancer (GC) is the fourth leading cause of cancer death worldwide. The intestinal type of GC is initiated by the pathogen Helicobacter pylori\, which infects half of the world’s population. The three biogenic polyamines\, putrescine\, spermidine\, and spermine play key functions in a variety of cellular processes and are essential for cellular homeostasis. Using animal models of H. pylori-mediated diseases\, we showed that the enzyme spermine oxidase (SMOX)\, which back-converts spermine to spermidine\, plays a major role in development of gastritis and gastric dysplasia. This occurs notably through the generation of acrolein\, a reactive aldehyde that initiates lipid peroxidation and further generation of bifunctional electrophiles. A potent scavenger of these molecules attenuates gastric carcinogenesis. Similar results were then obtained in models of sporadic or colitis-associated colorectal cancers.       \n📌 BBS conference room\, 2 rue Dr Hoffamnn Martinot – Bordeaux \n📆 16/07/2024\, 11 am
URL:https://www.bricbordeaux.com/en/event/invited-seminar-pr-alain-gobert-2024-07-16/
LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux
CATEGORIES:Meetings,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/07/invited-seminar-alain-gobert-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240702T140000
DTEND;TZID=Europe/Paris:20240702T170000
DTSTAMP:20240628T133356Z
CREATED:20240610T143409Z
LAST-MODIFIED:20240628T133356Z
UID:46960-1719928800-1719939600@www.bricbordeaux.com
SUMMARY:Lydia Dif thesis defense
DESCRIPTION:Lydia Dif\, Team 03 – Liver Cancers and Tumor Invasion. \nThesis direction Violaine Moreau \n“La fascine-1 en tant que cible thérapeutique dans l’hepatoblastome.” \n📆 Tuesday\, July 2\, 2pm \n📌 Amphi BBS\, 2 rue du Docteur Hoffmann Martinot Bordeaux (Carreire) \nNotice of defense with abstract available at this link
URL:https://www.bricbordeaux.com/en/event/lydia-dif-thesis-defense/
LOCATION:amphithéatre du BBS\, 2 rue Dr Hoffmann Martinot\, Bordeaux\, France
CATEGORIES:Meetings,Scientific seminars,Thesis defenses
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/06/soutenance-de-these-lydia-dif.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20240620
DTEND;VALUE=DATE:20240621
DTSTAMP:20240617T125331Z
CREATED:20240216T155252Z
LAST-MODIFIED:20240617T125331Z
UID:45841-1718841600-1718927999@www.bricbordeaux.com
SUMMARY:3D Biology Models Day June 20\, 2024
DESCRIPTION:Christine Varon\, head of team 04 (Digestive cancers associated with Helicobacter infection\, cancer stem cells and therapeutic strategies) and her scientific colleagues from Bordeaux are organizing a day of 3D models in biology. \n📆 June 20\, 2024 \n📌Domaine du Haut Carré \n👉 Free registration and abstract submission at this link:https://3dbio.sciencesconf.org/ \nThe deadline for registration and abstract submission has been extended to June 6. \nGreat news\, in addition to our great local speakers\, we will have the pleasure to welcome Xavier Gidrol (CEA Grenoble)\, one of the project leader of the recently granted PEPR MEDOOC! \nThe focus of the day is on three-dimensional cellular models developed in vitro for biology and medicine. These models\, which include organoids\, spheroids\, organs-on-a-chip and bioprinted tissues\, are currently undergoing exponential development\, thanks in particular to the coincidence between advances in stem cell biology and technologies enabling the topology and composition of the tissue microenvironment to be controlled. As well as being an alternative to animal models\, these models are of major interest for understanding developmental mechanisms\, disease modeling\, drug screening\, regenerative medicine and personalized medicine. This research is intrinsically interdisciplinary\, requiring the collaboration of biologists\, physicians\, physicists\, chemists and engineers.    \nThe aim of this first edition is to bring together people already using or wishing to develop these models\, to share their current or future projects. The day will enable the various local players to interact with each other\, pool their efforts and promote exchanges and collaborations.  \nPractical information \nThe day will be organized around thematic sessions\, with one invited paper and short communications (8 min + 2 min questions) per session. Coffee and lunch breaks will be accompanied by poster sessions. Abstracts for short communications and/or posters will be accepted from 15/02/2024.   \nOn-site only \nOrganizing committee  \nHugo De-Oliveira (Biotis) – Isabelle Dupin (CRCTB) – Elise Maurat (CRCTB) – Matthieu Raoux (CBMN) – Gaëlle Recher (LP2N) – Vincent Studer (IINS) – Christine Varon (BRIC)
URL:https://www.bricbordeaux.com/en/event/3d-biology-models-day-june-20-2024/
LOCATION:Agora du Haut Carré – Université de Bordeaux\, 43 rue Pierre Noailles\, Talence\, France
CATEGORIES:Meetings,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/02/vignette-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240617T133000
DTEND;TZID=Europe/Paris:20240617T170000
DTSTAMP:20240628T133415Z
CREATED:20240607T095518Z
LAST-MODIFIED:20240628T133415Z
UID:46950-1718631000-1718643600@www.bricbordeaux.com
SUMMARY:HDR defense Sandrine Poglio
DESCRIPTION:Sandrine Poglio\, univ. lecturerTeam 05 – Translational Research In Oncodermatology and Orphan skin diseases (TRIO2). will defend her HDR (Habilitation à Diriger la Recherche) on Monday June 17 at 1:30pm in the amphitheatre of the Centre de Génomique Fonctionnelle de Bordeaux\, site Carreire Université de Bordeaux (146 rue Leo Saignat). \n“Des cellules souches hématopoïétiques aux lymphocytes T tumoraux”  \nJury members: \nPr Katia Boniface\, PR\, Université de Bordeaux\nDr Erika Brunet\, DR INSERM\, Institut Imagine\, Paris\nDr Françoise PFLUMIO\, DR INSERM\, Laboratoire LSHL\, CEA-INSERM\, Fontenay-aux Roses\nDr Laurent Genestier\, DR INSERM\, CIRI\, Lyon\nPr Nicolas Ortonne\, PU-PH\, IMRB\, APHP\, Département de Pathology Hôpital Henri Mondor\, Créteil\nPr Jean-Philippe Merlio\, PU-PH\, CHU et Université de Bordeaux
URL:https://www.bricbordeaux.com/en/event/hdr-defense-sandrine-poglio/
LOCATION:salle de conférence CGFB – site Carreire\, 146 rue Leo Saignat\, Bordeaux\, 33000\, France
CATEGORIES:Meetings,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/06/soutenance-hdr-sandrine-poglio.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20240617
DTEND;VALUE=DATE:20240618
DTSTAMP:20240404T140706Z
CREATED:20240404T140706Z
LAST-MODIFIED:20240404T140706Z
UID:46420-1718582400-1718668799@www.bricbordeaux.com
SUMMARY:Science\, society and values symposium
DESCRIPTION:Science\, society and values symposium at Agora du Haut-Carré\, Talence. \nPr Andreas Bikfalvi (team1) is part of the organization of this symposium. \nFree admission with registration : https://form.jotform.com/240513496727360 \nProgram: \nSYMPOSIUM SCIENCE-SOCIETY VALUES-PROGRAM-final
URL:https://www.bricbordeaux.com/en/event/science-society-and-values-symposium/
LOCATION:Agora du Haut Carré – Université de Bordeaux\, 43 rue Pierre Noailles\, Talence\, France
CATEGORIES:Meetings,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/04/afiiche-symposium-science-societe-valeurs-juin-2024.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240614T143000
DTEND;TZID=Europe/Paris:20240614T170000
DTSTAMP:20240613T145205Z
CREATED:20240528T123755Z
LAST-MODIFIED:20240613T145205Z
UID:46756-1718375400-1718384400@www.bricbordeaux.com
SUMMARY:Thesis defense Alexia Calovoulos
DESCRIPTION:Alexia Calovoulos\, team 6 MIRCADE (Methods and Innovations for the Research in Pediatric Cancers) will present her thesis in Cell Biology and Pathophysiology.. \nThesis supervisor Christophe Grosset. \nTitle : “Study of the three-dimensional organization of hepatoblastoma tissues by volumetric imaging: Link to the Wnt/beta-catenin signaling pathway?” \n📆 Friday\, June 14 at 2:30 p.m. \nModule 2.6 batiment CROUS 2e étage (Carreire)\n146 rue Léo Saignat Bordeaux \nNotice of defense with abstract at this link \nThesis funded by the Région Nouvelle-Aquitaine and the Eva pour la Vie and Sphères associations.
URL:https://www.bricbordeaux.com/en/event/thesis-defense-alexia-calovoulos/
CATEGORIES:Meetings,Scientific seminars,Thesis defenses
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/05/soutenance-de-these-alexia-calovoulos.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240613T120000
DTEND;TZID=Europe/Paris:20240613T130000
DTSTAMP:20240614T081857Z
CREATED:20240425T161311Z
LAST-MODIFIED:20240614T081857Z
UID:46427-1718280000-1718283600@www.bricbordeaux.com
SUMMARY:BRIC technology seminar - Promega
DESCRIPTION:Our Technologies Group organizes this seminar with Promega \n  \nEnhancing your Research using Bioluminescent Technologies \nPresentation by Promega France :\nLudivine Sinzelle\, Key account Manager\, Responsable Grands Comptes Sud-Ouest\nFlorian Mignot\, Technical Support for Drug Discovery Solutions \nDetails in the poster. \n \n  \n  \n 
URL:https://www.bricbordeaux.com/en/event/bric-technology-seminar-promega/
LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux
CATEGORIES:Meetings,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/04/vignette-bric-techno-meeting-promega-bis.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240612T140000
DTEND;TZID=Europe/Paris:20240612T150000
DTSTAMP:20240610T133646Z
CREATED:20240531T133015Z
LAST-MODIFIED:20240610T133646Z
UID:46836-1718200800-1718204400@www.bricbordeaux.com
SUMMARY:SBM Department Seminar - Maxime Mahout
DESCRIPTION:Maxime Mahout \n“Décomposition des flux métaboliques des cellules en prolifération en Modes Elémentaires de Flux (EFMs). Application à la cellule cancéreuse moyenne” \n  \n📆 Wednesday June 12 at 2pm \n📌 ATTENTION ROOM CHANGE: amphitheatre in the BBS building\, 2 rue Dr Hoffmann Martinot\, Bordeaux\n \nSeminar organized by the Department of Biological and Medical Sciences (SBM) at the University of Bordeaux.
URL:https://www.bricbordeaux.com/en/event/sbm-department-seminar-maxime-mahout/
LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux
CATEGORIES:Meetings,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/05/seminaires-departement-sbm.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240610T100000
DTEND;TZID=Europe/Paris:20240610T110000
DTSTAMP:20240528T102518Z
CREATED:20240527T100339Z
LAST-MODIFIED:20240528T102518Z
UID:46744-1718013600-1718017200@www.bricbordeaux.com
SUMMARY:BRIC invited seminar: Pierre Chymkowitch
DESCRIPTION:Our unit invites Pierre Chymkowitch\,Associate Professor – Group leader: Transcriptional Regulation Of Cell Fate (Department of Biosciences – University of Oslo – Norway) to present its work at a special seminar. \n“Understanding the Role of Mitotic Chromosome Condensation and SUMOylation in Maintaining Cellular Identity and Homeostasis”. \n📆 Monday June 10 – 10 am\n📌 Bâtiment Bordeaux Biologie Santé – BBS\, 2 rue Dr Hoffmann Martinot\, 33000 Bordeaux\nzoom link on request (sarah.lesjean@inserm.fr)\n \n  \nAbstract:\nPreservation of gene expression patterns that define cellular identity is essential to perpetuate cellular lineages and preserve homeostasis. During this presentation I will feature published and unpublished data indicating how transcriptional and epigenetic identities are conserved throughout cell division and differentiation. Mitotic entry correlates with the condensation of the chromosomes\, changes in histone modifications\, exclusion of transcription factors from DNA\, and the broad downregulation of transcription. We found that preventing one chromosome to condense during mitosis causes it to fail resetting transcription. Rather\, in the following interphase\, the affected chromosome contains unusually high levels of the transcription machinery\, resulting in abnormally high gene expression levels\, including various transcription factors. This subsequently causes the activation of inducible transcriptional programs in trans\, even in the absence of the relevant stimuli. Thus\, mitotic chromosome condensation exerts stringent control on interphase gene expression to ensure the maintenance of cell identity across cell divisions (1). We used adipogenesis as a model to find that SUMOylation of chromatin-bound proteins ensures the precision of gene expression and transcription factor dynamics during differentiation (2). However\, the molecular mechanisms by which SUMOylation orchestrates the rewiring of transcriptional programs during initiation of differentiation remains to be established. Our unpublished data indicate that transient\, pharmacological inhibition of SUMOylation in human preadipocytes is sufficient to prime and activate specific enhancers and transcription factors. This causes irreversible hypertranscription of adipogenic genes\, leading to excessive fat accumulation. Given that epigenetic and transcriptional regulators are major SUMO targets\, we propose that SUMOylation maintains a chromatin landscape in undifferentiated cells\, which is critical to preserving the epigenetic fate of mature adipocytes\, protecting against unrestricted adipogenic transcription. This implies that the inherent adipogenic capacity of human adipose stem cells may be tied to SUMOylation and suggests an epigenetic basis for the inter-individual variability in fat accumulation. Using adipogenesis as a paradigm to uncover new molecular pathways by which SUMOylation sustains epigenetic fates\, we expect to contribute to a broader understanding of how transitory disruptions in epigenetic regulation induce stable homeostatic shifts and lead to disease\, like obesity and cancer (3).  \n\nRamos-Alonso\, L. et al. Mitotic chromosome condensation resets chromatin to safeguard transcriptional homeostasis during interphase. Proc Natl Acad Sci U S A 120\, e2210593120 (2023).   https://doi.org:10.1073/pnas.2210593120\nZhao\, X. et al. Waves of sumoylation support transcription dynamics during adipocyte differentiation. Nucleic Acids Res 50\, 1351-1369 (2022).   https://doi.org:10.1093/nar/gkac027\nParreno\, V. et al. Transient loss of Polycomb components induces an epigenetic cancer fate. Nature (2024).   https://doi.org:10.1038/s41586-024-07328-w\n\n  \nBio: \nI obtained a PhD from the University of Strasbourg in 2008. My research in the group of Jean-Marc Egly\, at the IGBMC\, was focused on revealing the origin of gene expression defects in patients with rare genetic disorders like Xeroderma pigmentosum (1). I then moved to Norway at the Dept. of Microbiology at Oslo Univ. Hospital. For the next eight years\, I continued my research in the group of JM. Enserink on gene regulation in the model organism Saccharomyces cerevisiae. The first four years were dedicated to revealing mechanisms that synchronize cell-cycle progression and gene expression (2). In the next four years I strated investigating the mechanisms regulated by the Small Ubiquitin-like Modifier SUMO at the chromatin level during adaptive response to stress (3) and started exploring the perpetuation of epigenetic and transcriptional memory throw-out mitosis (4). Next\, I started my group at Oslo Univ. Hospital and was appointed Associate Professor at the University of Oslo\, where I have been working since 2020. Our focus is unraveling the mechanisms supporting epigenetic and transcription fidelity (5) during cellular differentiation\, with a particular focus on how the SUMOylation pathway supports cellular fate (6\,7). References:  \n\nChymkowitch\, P.\, Le May\, N.\, Charneau\, P.\, Compe\, E. & Egly\, J. M. The phosphorylation of the androgen receptor by TFIIH directs the ubiquitin/proteasome process. EMBO J 30\, 468-479\n(2011).  https://doi.org:10.1038/emboj.2010.337\nChymkowitch\, P. et al. Cdc28 kinase activity regulates the basal transcription machinery at a subset of genes. Proc Natl Acad Sci U S A 109\, 10450-10455 (2012).   https://doi.org:10.1073/pnas.1200067109\nChymkowitch\, P. et al. TORC1-dependent sumoylation of Rpc82 promotes RNA polymerase III assembly and activity. Proc Natl Acad Sci U S A 114\, 1039-1044 (2017).   https://doi.org:10.1073/pnas.1615093114\nKruitwagen\, T.\, Chymkowitch\, P.\, Denoth-Lippuner\, A.\, Enserink\, J. & Barral\, Y. Centromeres License the Mitotic Condensation of Yeast Chromosome Arms. Cell 175\, 780-795 e715 (2018).  https://doi.org:10.1016/j.cell.2018.09.012\nRamos-Alonso\, L. et al. Mitotic chromosome condensation resets chromatin to safeguard transcriptional homeostasis during interphase. Proc Natl Acad Sci U S A 120\, e2210593120 (2023).   https://doi.org:10.1073/pnas.2210593120\nZhao\, X. et al. Waves of sumoylation support transcription dynamics during adipocyte differentiation. Nucleic Acids Res 50\, 1351-1369 (2022).   https://doi.org:10.1093/nar/gkac027\nBjune\, J.-I. et al. Mechanisms of the FTO locus association with obesity: Irx3 controls a sumoylation-dependent switch between adipogenesis and osteogenesis. bioRxiv\,\n2023.2010.2017.562662 (2023).  https://doi.org:10.1101/2023.10.17.562662
URL:https://www.bricbordeaux.com/en/event/bric-invited-seminar-pierre-chymkowitch/
LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux
CATEGORIES:Meetings,Scientific seminars
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240605T140000
DTEND;TZID=Europe/Paris:20240605T170000
DTSTAMP:20240527T074827Z
CREATED:20240524T145806Z
LAST-MODIFIED:20240527T074827Z
UID:46735-1717596000-1717606800@www.bricbordeaux.com
SUMMARY:HDR defense of François Moisan
DESCRIPTION:François Moisan\, researcher in Team 05 – Translational research in cutaneous oncology and rare skin diseases (TRIO2) will present his HDR (Habilitation to Supervise Research) on Wednesday June 5 at 2pm\, BBS amphitheater. \nSubject: Cellular and molecular mechanisms of the antitumor response to propranolol in vascular tumors. \nFrançois Moisan works on cutaneous vascular tumors and their therapy. The serendipity discovery of the effectiveness of propranolol on infantile hemangiomas (IH) in the team in 2008 led him\, upon his return from the USA in 2013\, to work on this mechanism of action. This work revealed that (1) IH is a tumor rich in norepinephrine (NE)\, one of the natural ligands of the beta-adrenergic pathway\, the expected target of treatment. (2) The cells making up the tumor (endothelial cells and pericytes) are capable of producing and secreting NE. (3) Anti-angiogenic effect is obtained through a competitive inhibition of NE by propranolol in vitro. He was also able to demonstrate (4) a third cell type which is key in the pathogenesis and response to propranolol: the telocyte. This stromal cell involved in cellular communication\, architecture and tissue remodeling\, including in the skin\, is revealed here (5) to overexpress aquaporin-1 modulated by propranolol. The development of in vitro coculture models relevant to this study makes it possible to explore the cellular and molecular mechanisms involved in the growth and regression of hemangiomas\, with the aim of identifying new therapeutic pathways for tumors and vascular abnormalities. The group he formed within the oncodermatology team (TRIO2) is also interested in angiomas associated with GNAQ mutations and angiosarcoma-type cancers.         \n 
URL:https://www.bricbordeaux.com/en/event/hdr-defense-of-francois-moisan/
LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux
CATEGORIES:Meetings,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/05/soutenance-hdr-f.-moisan.jpg
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240604T140000
DTEND;TZID=Europe/Paris:20240604T150000
DTSTAMP:20240531T132209Z
CREATED:20240531T132209Z
LAST-MODIFIED:20240531T132209Z
UID:46837-1717509600-1717513200@www.bricbordeaux.com
SUMMARY:SBM Department Seminar - Sigve Nakken
DESCRIPTION:Sigve Nakken\nInstitute for Cancer Research at Oslo University Hospital\, Norvège \n📆 4 june\, 2pm \n📌 IBGC (Carreire 146 rue Leo Saignat\, Bordeaux) \nSeminar organized by the Department of Biological and Medical Sciences (SBM) at the University of Bordeaux. \nA suite of computational frameworks to support precision cancer medicine \nCancer precision medicine is an approach to cancer treatment that tailors medical care to the individual characteristics of each patient and their tumor. A cornerstone of this approach is the use of high-throughput genomic profiling technologies for a deep characterization of the molecular features of tumor samples. The diversity and complexity of molecular read-outs\, combined with a rapidly evolving landscape of clinically actionable targets\, poses significant requirements for advanced data interpretation tools. In this talk\, I will present molecular data interpretation frameworks that we are actively developing to address the N-of-1 analytical challenge in precision oncology\, that is to highlight treatment opportunities for each complex cancer case in light of existing knowledge and large-scale reference datasets. Herein\, I will describe challenges and solutions with respect to molecular data integration and harmonization\, the adoption of standards for evaluating the clinical significance of genomic aberrations\, as well as the identification of relevant biomarker-guided clinical trials.     \nBio \nSigve Nakken works as a scientist at the Institute for Cancer Research at Oslo University Hospital\, Norway\, with affiliation to the Centre for Cancer Cell Reprogramming (CanCell)\, a Centre of Excellence at the University of Oslo. In addition\, he holds an Adjunct Professor position at the Department of Informatics\, University of Oslo. Nakken’s main interests are tool development for clinical interpretation of cancer genomes\, mechanisms and impact of DNA variation in cancer (soma and germline)\, and knowledge integration for precision cancer medicine. He has a background from computer science (MSc) and computational biology (PhD)\, and extensive experience with analysis of data from high-throughput sequencing technologies. He is the lead developer of multiple bioinformatics tools used in high-throughput cancer biology.
URL:https://www.bricbordeaux.com/en/event/sbm-department-seminar-sigve-nakken/
LOCATION:salle de conférence IBGC – Carreire\, 146 rue Leo Saignat\, Bordeaux\, 33000\, France
CATEGORIES:Meetings,Scientific seminars
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240527T100000
DTEND;TZID=Europe/Paris:20240527T153000
DTSTAMP:20240527T075055Z
CREATED:20240430T094546Z
LAST-MODIFIED:20240527T075055Z
UID:46507-1716804000-1716823800@www.bricbordeaux.com
SUMMARY:NEWMOON - Workshop "Targeting cell surface markers in oncology"
DESCRIPTION:The Réseau Recherche Impulsion NEWMOON (New Models in Oncology) is pleased to invite you to its workshop “Targeting cell surface markers in oncology” \nMonday\, May 27 10 a.m. to 3:30 p.m. \nThis workshop is co-organized by Sandrine Dabernat (team 8 BIOGO) and Clément Morgat (INCIAandemerging team I.Care). \nPrecision medicine in oncology hinges on targeting specific cell surface markers to hit tumor cells while sparing healthy tissue. Some of the known markers not only identify the tumor cells but also contribute to cellular behavior. Their identification can be the opportunity to reach the tumor with specific toxic therapies and contribute advancing personalized cancer care.   \nThis workshop gathers interdisciplinary experts who will share their knowledge and latest research on different ways to target tumor cell surface. \nProgram and registration at this link. \nRegistration deadline (free\, but mandatory): May 10\, 2024.
URL:https://www.bricbordeaux.com/en/event/newmoon-workshop-targeting-cell-surface-markers-in-oncology/
LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux
CATEGORIES:Meetings,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/04/workshop-newmoon-may.jpg
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240525T100000
DTEND;TZID=Europe/Paris:20240525T163000
DTSTAMP:20240507T123505Z
CREATED:20240429T090327Z
LAST-MODIFIED:20240507T123505Z
UID:46604-1716631200-1716654600@www.bricbordeaux.com
SUMMARY:Brain cancer open day on 25 May 2024
DESCRIPTION:Do you know what brain cancer is? the causes ? the consequences? If there is any treatments ? 🧠 \nCome and discover BRIC team 1 working on brain cancers on  25 May from 10am to 4pm.  \n  \n The programme includes : \n\n– Exchanges with our teams \n– Workshops led by researchers \n– Scientific mediation on cancer and brain cancers \n– Interactive visits to the laboratory \n– Interactive mini-seminars on cancer and brain cancers.  \n  \nHow do I get there?  \n👉 Take tram B to Doyen Drus or François Bordes (PRM access via François Bordes) \nOr by car\, parking in avenue Léon Duguit\, 33600 Pessac. \nBuilding B2\, 33600 Pessac
URL:https://www.bricbordeaux.com/en/event/brain-cancer-open-day-on-25-may-2024/
CATEGORIES:Meetings,Scientific seminars
ATTACH;FMTTYPE=image/png:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/04/vignette-journee-cancer-du-cerveau-1.png
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240514T193000
DTEND;TZID=Europe/Paris:20240514T233000
DTSTAMP:20240507T085014Z
CREATED:20240426T123304Z
LAST-MODIFIED:20240507T085014Z
UID:46588-1715715000-1715729400@www.bricbordeaux.com
SUMMARY:Profession: virus trainer!
DESCRIPTION:\nWhat are viruses good for? \n\nCome and meet Jean-Marc Blouin\, researcher with Team 8 (genetic biotherapies and oncology – BioGO)\, who is taking part in the Pint of Science festival  from May 13 to 15. This event\, which seeks to demystify science\, will focus on the usefulness of viruses in destroying or curing diseased cells on May 14! Interesting\, isn’t it? \n\nIn the first part of this meeting\,  Véronique Guyonnet-Dupérat (Technical Director of the Vect’UB vectorology core facility) will talk about the use of viruses to help heal diseased red blood cells. Then\, Jean-Marc Blouin will explain how heme (a molecule present in our cells and used to bind oxygen in blood cells) can make cancer cells photosensitive and facilitate their destruction by laser. \n\nFrom 7.30pm at HMS Victory\, 3 place Général Sarrail\, 33000\, Bordeaux\, don't forget to get your tickets via the following link: https://pintofscience.fr/event/on-dresse-les-virus-pour-quils-nous-soignent 
URL:https://www.bricbordeaux.com/en/event/profession-virus-trainer/
LOCATION:HMS Victory\, 3 place Général Sarrail\, 33000\, Bordeaux\,\, 3 place Général Sarrail\, Bordeaux\, 33000\, France
CATEGORIES:Meetings,Scientific seminars
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240509T080000
DTEND;TZID=Europe/Paris:20240509T170000
DTSTAMP:20240502T093250Z
CREATED:20240502T093250Z
LAST-MODIFIED:20240502T093250Z
UID:46606-1715241600-1715274000@www.bricbordeaux.com
SUMMARY:The Course du Petit Prince !
DESCRIPTION:On 9 May 2024\, the Course du Petit Prince will take place in the Bourgailh forest\, 160 av. de Beutre 33600 Pessac en Gironde(33). This charity event highlights the fight against sarcomas (malignant tumours that develop in bone and/or soft tissue) by donating all profits to the national RHU CONDOR university hospital research programme. \nTeam 9\, Sarcotarget\, is based at the Institut Bergonié and headed by Antoine Italiano. \nFor young and old alike\, this all-ages run or walk offers trails of 1 or 2 km for children and 7 to 15 km for adults. Safe\, signposted and supervised\, come and have fun while doing a good deed! \nFor further information on the race\, click on the following link:= >https://coursedupetitprince.fr/course
URL:https://www.bricbordeaux.com/en/event/the-course-du-petit-prince/
LOCATION:Bourgailh 160 av. de Beutre 33600 Pessac en Gironde(33)\, 160 av. de Beutre\, Pessac\, 33600\, France
CATEGORIES:Meetings,News
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/05/course-du-petit-prince.jpg
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240506T180000
DTEND;TZID=Europe/Paris:20240506T200000
DTSTAMP:20240426T120035Z
CREATED:20240426T094701Z
LAST-MODIFIED:20240426T120035Z
UID:46447-1715018400-1715025600@www.bricbordeaux.com
SUMMARY:Soirée Mollat/CHU - Infertility: the environment in question? Lucie Chansel-Debordeaux's intervention
DESCRIPTION:As part of the Soirées Santé program\, Bordeaux University Hospital and Librairie Mollat are organizing an evening on the theme of infertility: the environment in question? \nGuests:  \nLucie Chansel-Debordeaux\, reproductive biologist\, head of the Reproductive Biology Department – CECOS and MCU-PH team 8 Biotherapies Genetics and Oncology (BioGO)  in our BRIC Unit – BoRdeaux Institut of Oncology (INSERM – Université de Bordeaux). \nFleur Delva\, public health doctor\, coordinator of the ARTEMIS center\, an environmental health prevention platform  dedicated to reproduction\, and researcher in the EPICENE team at Bordeaux Public Health  (INSERM – Université de Bordeaux). \n\n\nInfertility directly affects over three million people in France\, a figure that is rising every year. The rise in infertility is primarily due to the fact that women are now giving birth to their first child an average of 5 years later than forty years ago. It can also be linked to medical causes such as endometriosis in women or genetic abnormalities in men.   So the origin of infertility can be multifactorial\, and more and more scientific data suggests an environmental effect.\n\nOccupational and non-occupational environmental exposure to chemical substances is recognized as being able to interfere with the entire reproductive process (fertility disorders\, pregnancy pathologies\, developmental abnormalities). Numerous studies describe a link between exposure to certain families of chemical substances – endocrine disruptors – and fertility disorders. Exposure to these substances may have direct effects on gametes\, but evidence also suggests longer-term effects\, increasing the risk of chronic disease in childhood and adulthood (the developmental origins of health and disease “DOHAD” hypothesis).  What’s more\, throughout their lives\, individuals are exposed to multiple environmental factors that can have an impact on their health and that of future generations. The term “exposome” refers to the totality of an individual’s exposures over the course of a lifetime. We’ll be taking a closer look at these different aspects during the conference\, as well as the preventive measures that can be implemented.  \n\n\n📆 May 6 6-8 p.m.\n📌 Station Ausone\, 8 rue de la Vieille Tour\, Bordeaux\n\nor online on the Mollat and CHU bookshop networks (YouTube link)\nFree admission
URL:https://www.bricbordeaux.com/en/event/soiree-mollat-chu-infertility-the-environment-in-question-lucie-chansel-debordeauxs-intervention/
LOCATION:Station Aussone\, 8 rue de la Vieille Tour\, Bordeaux\, France
CATEGORIES:Meetings,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/04/conf-infertilite-lucie-chansel.jpg
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240504T090000
DTEND;TZID=Europe/Paris:20240504T123000
DTSTAMP:20240426T132744Z
CREATED:20240426T132744Z
LAST-MODIFIED:20240426T132744Z
UID:46468-1714813200-1714825800@www.bricbordeaux.com
SUMMARY:OPEN DOORS : Raising awareness of skin cancer
DESCRIPTION:Our institute’s “Translational Research in Cutaneous Oncology and Rare Skin Diseases (TRIO2)” research team opens its laboratory doors to the public on Saturday\, May 4\, 2024. [\n  \nThe program includes a tour of the laboratories\, a conference and participatory workshops from 9am to 12:30pm. You’ll learn all about these types of cancer\, current treatments and future advances.  \nWorkshops \n\nCell culture: Discovering a culture room\nHistology: Demonstration of the techniques used to prepare anatomopathology slides\nMicroscopy: Observation of stained and fluorescent slides\nChromosome: Observation of chromosome labeling\n\n 9:15am-11am or 10:45am-12:30pm (doors open 15 minutes for each time slot) \nBâtiment Bordeaux Biologie Santé (BBS) 2 rue du Dr Hoffmann Martinot – Bordeaux
URL:https://www.bricbordeaux.com/en/event/open-doors-raising-awareness-of-skin-cancer/
LOCATION:Accueil bâtiment Bordeaux Biologie Santé (BBS)\, 2 rue Dr Hoffmann Martinot\, Bordeaux\, France
CATEGORIES:Meetings,Scientific seminars
ATTACH;FMTTYPE=image/png:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/04/journee-portes-ouvertes-cancer-de-la-peau-2.png
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240419T080000
DTEND;TZID=Europe/Paris:20240419T170000
DTSTAMP:20240419T101016Z
CREATED:20240419T101016Z
LAST-MODIFIED:20240419T101016Z
UID:46469-1713513600-1713546000@www.bricbordeaux.com
SUMMARY:HDR defense Amélie Guitart
DESCRIPTION:Defense for Habilitation to Supervise Research in Life and Health Sciences \n“Cellules souches hématopoïétiques et leucémies”\nPresented by Ms Amélie GUITART\, CR team 10\nMonday\, April 22\, 2024 at 1:30 p.m.\nBâtiment Bordeaux Biologie Santé\, 2 avenue Dr Hoffmann Martinot\, 33000 Bordeaux \nJury :\nMme Françoise PFLUMIO\, Directrice de recherche\, Université de Paris – Rapporteure\nMme Françoise PORTEU\, Directrice de recherche\, Université de Paris – Rapporteure\nM Philippe BRUNET DE LA GRANGE\, Directeur de recherche\, Université de Bordeaux – Rapporteur\nMme Chloé JAMES\, PU-PH\, Université de Bordeaux – Examinatrice\nM Bastien GERBY\, Chargé de recherche\, Université de Toulouse – Examinateur
URL:https://www.bricbordeaux.com/en/event/hdr-defense-amelie-guitart/
CATEGORIES:Meetings,Scientific seminars
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20240405
DTEND;VALUE=DATE:20240406
DTSTAMP:20240311T165329Z
CREATED:20240308T141214Z
LAST-MODIFIED:20240311T165329Z
UID:45980-1712275200-1712361599@www.bricbordeaux.com
SUMMARY:Bordeaux Cell Biology Gathering (BCBG)
DESCRIPTION:The “Bordeaux Cell Biology Gathering” (BCBG) is a day-long event to which all those in the Bordeaux metropolitan area with an interest in Cell Biology are invited. The aim of this event is to facilitate encounters between researchers and create a closer relationship with students. The speakers are all from Bordeaux\, who are keen to present their work in an informal and convivial way. \n📆 April 5\, 2024 \n📌 Agora du Haut Carré – Talence \n👉 Program and registration: at this link \nThe researchers from our BRIC unit taking part in this edition: \nFrederic Saltel\, unit director and team 3 co-leader: member of the organizing committee\, with M. Bonhivers (MFP)\, S. Mongrand (LBM)\, O. Rossier (IINS) and I. Sagot (IBGC). \nViolaine Moreau\, team 3 co-leader: session 4 moderator \nFrançois Moisan\, researcher team 5: “Cellular network and dynamic interactions of Telocytes in tumor angiogenesis\, new insights form large volume imaging and 3D model of Infantile Hemangioma.” (9h40) \nCloé Tessier\, PhD student\, team 1: “Dynamics of lipid droplets in glioblastoma” (12h) \nLucile Rouyer\, PhD student\, team 3: “3D model to understand hepatocellular carcinoma progression: Investigating the interface between normal liver and HCC cells” (16h)
URL:https://www.bricbordeaux.com/en/event/bordeaux-cell-biology-gathering-bcbg/
LOCATION:Agora du Haut Carré – Université de Bordeaux\, 43 rue Pierre Noailles\, Talence\, France
CATEGORIES:Meetings,Scientific seminars
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240326T200000
DTEND;TZID=Europe/Paris:20240326T210000
DTSTAMP:20240325T161701Z
CREATED:20240325T161701Z
LAST-MODIFIED:20240325T161701Z
UID:46168-1711483200-1711486800@www.bricbordeaux.com
SUMMARY:Pr Emeritus Jacques Robert online conference - "Cancer and charlatanism".
DESCRIPTION:AFIS\, Association Française pour l’Information Scientifique\, is organizing an online conference with Professor Emeritus Jacques Robert on Tuesday March 26 at 8pm. \nAll information and registration at this link. \nCancers have been a particular source of inspiration for charlatans\, naturopaths and crudivores. Cancers carry a strong emotional charge\, are seen as a curse\, and carcinophobia leads people who are well-informed and thoughtful to turn to solutions that defy common sense and reason. If “alternative” methods of preventing and curing cancer proved as effective as they are\, the disease would have been eradicated a long time ago. And yet\, each year sees its share of charlatans appear on the juicy market of alternative “medicines” and prosper\, who with a miracle diet\, who with a new “revolutionary” treatment. Quackery is certainly dangerous on an individual level\, and famous names such as Steve McQueen and Steve Jobs have paid the price. But it is also dangerous on a collective level\, as it insidiously spreads false ideas and vain hopes throughout the population\, thus contributing to the spread of pernicious sectarian phenomena. During this webconference\, Jacques Robert will take stock of these charlatanisms and the dangers they represent. Jacques Robert is Professor Emeritus of Oncology at the University of Bordeaux since September 2019. In this capacity\, he is a member of Team 2 (Reprogramming of tumor activity and the associated microenvironment – Rytme) and an honorary hospital practitioner at the Institut Bergonié\, the Bordeaux Cancer Center\, where he headed the biochemistry laboratory for over 35 years.
URL:https://www.bricbordeaux.com/en/event/pr-emeritus-jacques-robert-online-conference-cancer-and-charlatanism/
CATEGORIES:Meetings,Scientific seminars
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240326T140000
DTEND;TZID=Europe/Paris:20240326T180000
DTSTAMP:20240307T112351Z
CREATED:20240307T112351Z
LAST-MODIFIED:20240307T112351Z
UID:45943-1711461600-1711476000@www.bricbordeaux.com
SUMMARY:Thematic seminar “Spatial transcriptomics”
DESCRIPTION:As part of the second thematic seminar organized by the Department of Biological and Medical Sciences (SBM) “Spatial Transcriptomics”\, Jeffrey R. Moffitt from Harvard Medical School and Dieter Henrik Heiland from the Medical Center of the University of Friborg will give a lecture. \nThis event is organized by Majid Khatib\, head of team 02 – Reprogramming of tumor activity and the associated microenvironment (Rhytme) of our BRIC unit and Thomas Daubon of the IBCG\, in collaboration with the department’s Seminars GT. \n📆 Tuesday March 26 at 2 p.m. \n📌amphitheater of the BBS building\, Carreire campus\, 2 rue Dr Hoffmann Martinot Bordeaux. \n\nSpatial transcriptomics is an innovative method that allows mapping gene expression at a spatial scale in complex biological tissues. Unlike traditional techniques which measure gene expression from homogenized tissue extracts\, spatial transcriptomics makes it possible to preserve information on the cellular localization of messenger RNAs. This emerging field offers significant advantages for understanding pathologies. By mapping gene expression within tissues\, researchers can identify specific cell types involved in disease processes\, understand the interactions between these cells\, and reveal the molecular alterations associated with diseases. Spatial transcriptomics offers a new perspective for studying pathologies by allowing detailed visualization of gene expression inside tissues\, which paves the way for a better understanding of disease mechanisms and more targeted therapeutic strategies.    \n In this context\, Majid Khatib (BRIC) and Thomas Daubon (IBGC)\, the organizers\, invited Jeffrey R. Moffitt (Harvard Medical School) and Dieter Henrik Heiland (Medical Center University of Freiburg). For an hour and a half\, these experts will address this topic of general interest for all members of the department. For this second edition\, doctoral and post-doctoral students are encouraged to present 5-minute flash communications in order to stimulate discussion with the speakers and the audience. They can also share preliminary results. Are you a researcher and would like to chat with guests?  \n Please contact candice.menegon@u-bordeaux.fr to set up meeting slots. \nProgram: \n\n14h: Jeffrey R. Moffitt et Dieter Henrik Heiland\,\n15h30: 5 minute flash communication\n16h: cocktail\n17h: Round table for young researchers
URL:https://www.bricbordeaux.com/en/event/thematic-seminar-spatial-transcriptomics/
LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux
CATEGORIES:Meetings,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/03/transcriptomique-spatiale-2024-03-26.jpg
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240323T091500
DTEND;TZID=Europe/Paris:20240323T123000
DTSTAMP:20240321T152658Z
CREATED:20240315T104916Z
LAST-MODIFIED:20240321T152658Z
UID:46124-1711185300-1711197000@www.bricbordeaux.com
SUMMARY:Open house: raising awareness of stomach cancer
DESCRIPTION:Come one\, come all to this open morning dedicated to raising awareness of stomach cancer! \nTheTeam 04 – Helicobacter-associated digestive cancers\, cancer stem cells and therapeutic strategies headed by Christine Varon\, and the team associated with the Centre National de Référence des Campylobacters et Hélicobacters CNRCH\, welcome you in two slots. \nFull details in this poster.
URL:https://www.bricbordeaux.com/en/event/open-house-raising-awareness-of-stomach-cancer/
LOCATION:Accueil bâtiment Bordeaux Biologie Santé (BBS)\, 2 rue Dr Hoffmann Martinot\, Bordeaux\, France
CATEGORIES:Meetings,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/03/vignette-portes-ouvertes-sensibilisation-cancer-de-lestomac.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240319T140000
DTEND;TZID=Europe/Paris:20240319T150000
DTSTAMP:20240307T152128Z
CREATED:20240307T152128Z
LAST-MODIFIED:20240307T152128Z
UID:45950-1710856800-1710860400@www.bricbordeaux.com
SUMMARY:Seminar by Nelson Dusetti invited by Majid Khatib
DESCRIPTION:Nelson Dusetti : “Developing Transcriptomic Signatures through Preclinical Models for Personalized Pancreatic Cancer Treatment” \nNelson Dusetti\, Cancer Research Center of Marseille (CRCM) is invited by Majid Khatib (BRIC) for a seminar on March 19 in the IBGC conference room. \nPancreatic cancer remains one of the most aggressive and lethal malignancies\, necessitating the exploration of personalized treatment strategies. Transcriptomic analysis has emerged as a powerful tool for understanding the molecular intricacies of pancreatic cancer and tailoring therapeutic interventions. In this study\, we employed preclinical models to elucidate transcriptomic signatures associated with pancreatic cancer progression and treatment response. Through integrative analysis of gene expression profiles\, we identified key molecular pathways and biomarkers implicated in disease pathogenesis and therapeutic resistance. Furthermore\, utilizing patient-derived xenografts and organoid cultures\, we validated the clinical relevance of our findings and assessed the efficacy of targeted therapies in a personalized manner. Our results underscore the potential of transcriptomic signatures derived from preclinical models to guide the development of personalized treatment strategies for pancreatic cancer patients\, ultimately improving clinical outcomes and advancing precision oncology.      \n——————————————————————————————————————————————– \nNelson Dusetti is an oncology researcher dedicated to advancing personalized treatments for pancreatic cancer. As Co-Lead of the Department and Team Lead for Translational and Therapeutic Targets Research in Pancreatic Cancer\, his work is focused on developing innovative approaches to address the challenges of individualized chemotherapy regimens. His research emphasizes the importance of predictive biomarkers in guiding treatment decisions\, particularly in the context of limited druggable targets in advanced pancreatic cancer tumors. Dusetti’s recent study highlights the potential of comprehensive transcriptomic analysis to predict chemotherapy responses\, providing valuable insights into treatment outcomes. By integrating microenvironmental factors and employing AI-based predictive tools Dusetti and his team have made significant strides in optimizing treatment selection and improving patient outcomes. His ongoing efforts are now directed towards refining these approaches for seamless integration into routine clinical practice\, ultimately ensuring the effective transfer of their studies to the everyday care of pancreatic cancer patients. Additionally\, Dusetti is a Co-Founder and CSO of Predicting Med\, a pioneering startup dedicated to commercializing molecular tests for chemotherapy in pancreatic ductal adenocarcinoma.
URL:https://www.bricbordeaux.com/en/event/seminar-by-nelson-dusetti-invited-by-majid-khatib/
LOCATION:salle de conférence IBGC – Carreire\, 146 rue Leo Saignat\, Bordeaux\, 33000\, France
CATEGORIES:Meetings,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/03/nelson-dusetti-invite-m-khatib.jpg
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240316T100000
DTEND;TZID=Europe/Paris:20240316T170000
DTSTAMP:20240408T204300Z
CREATED:20240223T134625Z
LAST-MODIFIED:20240408T204300Z
UID:45944-1710583200-1710608400@www.bricbordeaux.com
SUMMARY:Our scientists meet the public for Cancer Week
DESCRIPTION:Come and meet us at the Place Pey Berland (Bordeaux) on March 16\, 2024\, during the national cancer week. \nOur laboratory\, which brings together the majority of cancer research teams in Bordeaux\, is delighted to offer you a day of exchange. \nOn this occasion\, our scientific community will present its missions and objectives. We’ll be offering fun activities and information about cancer research. We’ll also be on hand to answer any questions you may have about research.  \nThis event is organized with the support of the City of Bordeaux \nCome one\, come all!
URL:https://www.bricbordeaux.com/en/event/our-scientists-meet-the-public-for-cancer-week/
LOCATION:place Pey Berland Bordeaux\, place Pey Berland\, Bordeaux\, France
CATEGORIES:Meetings,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/02/journee-grand-public-bric-2024-pey-berland-vignette-2.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20240316T100000
DTEND;TZID=Europe/Paris:20240316T170000
DTSTAMP:20240408T204318Z
CREATED:20240222T114929Z
LAST-MODIFIED:20240408T204318Z
UID:45850-1710583200-1710608400@www.bricbordeaux.com
SUMMARY:Meet the scientists for Cancer Week
DESCRIPTION:Come and meet us at the Place Pey Berland (Bordeaux) on March 16\, 2024\, during the national cancer week. \n \nOur laboratory\, which brings together the majority of cancer research teams in Bordeaux\, is delighted to offer you a day of exchange. Our scientific community will be on hand to present its missions and objectives. \n We’ll be offering fun activities and information about cancer research. We’ll also be on hand to answer any questions you may have about research.  \nThis event is organized with the support of the City of Bordeaux
URL:https://www.bricbordeaux.com/en/event/meet-the-scientists-for-cancer-week/
LOCATION:place Pey Berland Bordeaux\, place Pey Berland\, Bordeaux\, France
CATEGORIES:Meetings
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/02/journee-grand-public-bric-2024-pey-berland-vignette-1.jpg
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END:VCALENDAR