BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Bordeaux Institute of Oncology - ECPv6.17.3.1//NONSGML v1.0//EN CALSCALE:GREGORIAN METHOD:PUBLISH X-WR-CALNAME:Bordeaux Institute of Oncology X-ORIGINAL-URL:https://www.bricbordeaux.com/en/ X-WR-CALDESC:Events for Bordeaux Institute of Oncology REFRESH-INTERVAL;VALUE=DURATION:PT1H X-Robots-Tag:noindex X-PUBLISHED-TTL:PT1H BEGIN:VTIMEZONE TZID:Europe/Paris BEGIN:DAYLIGHT TZOFFSETFROM:+0100 TZOFFSETTO:+0200 TZNAME:CEST DTSTART:20230326T010000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:+0200 TZOFFSETTO:+0100 TZNAME:CET DTSTART:20231029T010000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:+0100 TZOFFSETTO:+0200 TZNAME:CEST DTSTART:20240331T010000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:+0200 TZOFFSETTO:+0100 TZNAME:CET DTSTART:20241027T010000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:+0100 TZOFFSETTO:+0200 TZNAME:CEST DTSTART:20250330T010000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:+0200 TZOFFSETTO:+0100 TZNAME:CET DTSTART:20251026T010000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:+0100 TZOFFSETTO:+0200 TZNAME:CEST DTSTART:20260329T010000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:+0200 TZOFFSETTO:+0100 TZNAME:CET DTSTART:20261025T010000 END:STANDARD END:VTIMEZONE BEGIN:VEVENT DTSTART;TZID=Europe/Paris:20250403T120000 DTEND;TZID=Europe/Paris:20250403T130000 DTSTAMP:20250401T100244Z CREATED:20250331T154329Z LAST-MODIFIED:20250401T100244Z UID:49016-1743681600-1743685200@www.bricbordeaux.com SUMMARY:Leica - Seminar and demonstration of the Confocal Stellaris microscope DESCRIPTION:LEICA will be at BBS on April 2 and 3\, 2025\, to demonstrate the Confocal Stellaris microscope.\n\n\nClément Laigle\, LEICA Applications Engineer\, will present the various acquisition options at a unit seminar on Thursday April 3\, from 12 noon to 1 pm.\nTo register\, see email sent by Walid Mahfouf on 26/03. If you are not from BRIC\, contact walid.mahfouf@u-bordeaux.fr \nDemo sessions last from 1h to 1h30 and are open to 3 people. You can reserve your slots on the ENT reservation site in the “BBS4-Demo Stellaris” resource family. \n\nLeica contact:\nAndy Tempez\nProduct Specialist Confocal Microscopy\nFrance South\nandy.tempez@leica-microsystems.com\nMobile : +33 6 74 40 34 72 URL:https://www.bricbordeaux.com/en/event/leica-seminar-and-demonstration-of-the-confocal-stellaris-microscope/ LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux CATEGORIES:Meetings,Scientific seminars ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2025/03/leica-seminaire-avril-2025-bric.jpg END:VEVENT BEGIN:VEVENT DTSTART;VALUE=DATE:20250319 DTEND;VALUE=DATE:20250322 DTSTAMP:20241219T151854Z CREATED:20241219T151854Z LAST-MODIFIED:20241219T151854Z UID:48530-1742342400-1742601599@www.bricbordeaux.com SUMMARY:Annual Congress of the French Society for Gene and Cell Therapy (SFTCG) DESCRIPTION:Annual congress of the French Society for Gene and Cell Therapy (SFTCG)\, organized by François Moreau-Gaudry (team 8\, Biotherapies Génétique et Oncologie -BioGO).\n\n \n \n March 19 to 21\, 2025\n \n Agora du Haut Carré\, Talence. \n \n Free registration for students submitting an abstract\n \n \n \n https://www.sftcg.fr/annual-congress URL:https://www.bricbordeaux.com/en/event/annual-congress-of-the-french-society-for-gene-and-cell-therapy-sftcg/ LOCATION:Agora du Haut Carré – Université de Bordeaux\, 43 rue Pierre Noailles\, Talence\, France CATEGORIES:Meetings ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/12/colloque-sftcg-2025-03-2.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Paris:20250318T140000 DTEND;TZID=Europe/Paris:20250318T170000 DTSTAMP:20250224T155724Z CREATED:20250224T155724Z LAST-MODIFIED:20250224T155724Z UID:48924-1742306400-1742317200@www.bricbordeaux.com SUMMARY:SBM Department thematic seminar "Inflammation in health and diseases" DESCRIPTION:The Biological and Medical Sciences Department’s (SBM) first thematic seminar of the year 2025 on “Inflammation in Health and Diseases” will be held on Tuesday March 18\, 2025 at 2:00 pm in the amphitheater of the BBS building\, on the Carreire campus. \nAksam Merched\, team 6 BRIC is organizing this seminar with Vanja Sisirak from ImmunoConcept in collaboration with the Department’s Seminar WG. \nSpeakers: \n\nDr. Magnus BACK \, MD\, PhD (Karolinska Institute)\nDr. Emmanuel Laurent GAUTIER \, PhD (Sorbonne University)\n\nIn addition to the main presentations\, we invite doctoral and post-doctoral students to present their work on this theme in a 5-minute “flash presentation” format. \nThe seminar will be followed by a round-table discussion over a convivial drink in the BBS cafeteria. \nWould you like to participate as a speaker (flash presentation) or attend the round table?\nRegister now! URL:https://www.bricbordeaux.com/en/event/sbm-department-thematic-seminar-inflammation-in-health-and-diseases/ LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux CATEGORIES:Meetings,Scientific seminars ATTACH;FMTTYPE=image/png:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2025/02/thematicseminar-18-03-2025.png END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Paris:20250210T110000 DTEND;TZID=Europe/Paris:20250210T120000 DTSTAMP:20250128T102442Z CREATED:20250128T101647Z LAST-MODIFIED:20250128T102442Z UID:48734-1739185200-1739188800@www.bricbordeaux.com SUMMARY:Maria Rodriguez-Colman - Team 1 BRIC Invited seminar DESCRIPTION:Maria Rodriguez-Colman\, PhD. Associate Professor at Center for Molecular Medicine (CMM)\, University Medical Centrum Utrecht (UMC Utrecht)\, The Netherlands\, invited by Lucie Brisson and Thomas Mathivet\, team 1 BRIC. \n“Driving forces: Metabolism in tumor development dynamics” \nThe Rodriguez Colman Lab investigates the Metabolism of Stem Cells and Cancer. We use organoids as model systems\, heterocellular structures that recapitulate the complexity of in vivo tissue dynamics\, including stem cell differentiation and cellular plasticity. Our research integrates bioenergetics\, metabolomics\, and other omics approaches with cutting-edge 4D live imaging to capture metabolic changes across different scales with high temporal resolution. By genetically introducing fluorescent-based reporters\, we monitor metabolite levels within distinct cellular compartments while simultaneously tracking cell type specification. This long-term live imaging data is analyzed using machine learning-based single-cell tracking coupled with advanced analytical pipelines. In this presentation\, I will discuss our findings on how lactate\, traditionally considered a metabolic waste product of tumors\, plays a regulatory role in cancer stem cell differentiation and plasticity through the epigenetic modulation of oncogenes such as MYC. \n www.RodriguezColmanLab.org \n  URL:https://www.bricbordeaux.com/en/event/maria-rodriguez-colman-team-1-bric-invited-seminar/ LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux CATEGORIES:Meetings,Scientific seminars ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2025/01/invited-seminar-maria-rodriguez-colman-2025-02-10.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Paris:20241220T100000 DTEND;TZID=Europe/Paris:20241220T140000 DTSTAMP:20241212T101800Z CREATED:20241212T101800Z LAST-MODIFIED:20241212T101800Z UID:48363-1734688800-1734703200@www.bricbordeaux.com SUMMARY:Camille Tocqueville thesis defense - MIRCADE team - BRIC DESCRIPTION:Camille Tocqueville‘s thesis defense\, team 06 – MIRCADE (Methods and Innovations for Childhood Cancer Research). \nThesis director Philippe VESCHAMBRE \nPhD specialty: Cancer biology. \n“Implication de la Striatin3 dans la régulation des voies Wnt et Hippo dans le carcinome hépatocellulaire et son rôle de suppresseur de tumeur dans l’hépatoblastome” \nFriday\, December 20\, 10 a.m. \nAmphi BBS\, 2 rue du Dr Hoffmann Martinot\, Bordeaux \nNotice of thesis defense at this link URL:https://www.bricbordeaux.com/en/event/camille-tocqueville-thesis-defense-mircade-team-bric/ LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux CATEGORIES:Meetings,Scientific seminars,Thesis defenses ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/12/soutenance-de-these-camille-tocqueville-bric.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Paris:20241216T123000 DTEND;TZID=Europe/Paris:20241216T170000 DTSTAMP:20241213T111802Z CREATED:20241213T111802Z LAST-MODIFIED:20241213T111802Z UID:48446-1734352200-1734368400@www.bricbordeaux.com SUMMARY:Mariella Spalato-Ceruso thesis defense - team 9 BRIC DESCRIPTION:thesis defense Dr Mariella Spalato-Ceruso\, team 9 Sarcotarget \nPhD specialization: Cell Biology and Pathophysiology \nTitle : Profil génomique et immunologique des sarcomes métastatiques des tissus mous. \nMonday\, December 16 – 12:30 p.m. \nMeeting Room 7th floor\nInstitut Bergonié Building G\n229 Cours de l’Argonne 33000 Bordeaux \nNotice of defense at this link URL:https://www.bricbordeaux.com/en/event/mariella-spalato-ceruso-thesis-defense-team-9-bric/ LOCATION:Institut Bergonié\, 229 Cours de l'Argonne\, Bordeaux\, 33076\, France CATEGORIES:Meetings,Scientific seminars,Thesis defenses ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/12/soutenance-de-these-mariella-spalato-team-9.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Paris:20241213T140000 DTEND;TZID=Europe/Paris:20241213T170000 DTSTAMP:20241212T140913Z CREATED:20241203T153913Z LAST-MODIFIED:20241212T140913Z UID:48321-1734098400-1734109200@www.bricbordeaux.com SUMMARY:Thesis defense Clément Marcelin\, team 4 DESCRIPTION:Clément Marcelin\, Team 04 – Helicobacter-associated digestive cancers\, cancer stem cells and therapeutic strategies \nThesis director Nicolas Grenier \nPhD specialization: Bioimaging \nTitle : Combinaison de Modèles Expérimentaux et Cliniques pour l’Évaluation de la Thermométrie IRM \nSalle broussin Delorme and visio\nCHU Bordeaux Pellegrin\, Service d’imagerie médicale. \nFriday\, December 13\, 2pm \nJury members: \n\nPr. Vania Tacher\, Hopital Henri-Mondor\, Créteil\, rapporteur\nPr. Julien Frandon\, CHU Nîmes\, rapporteur\nPr. Nicolas Grenier\, Directeur de thèse\nPr. Hélène Vernhet-Kovacsik\, Hôpital Arnaud de Villeneuve\, Montpellier\nDr Eva Jambon\, CHU Bordeaux\n\nNotice of thesis defense at this link. URL:https://www.bricbordeaux.com/en/event/thesis-defense-clement-marcelin-team-4/ CATEGORIES:Meetings,Scientific seminars,Thesis defenses ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/12/soutenance-de-these-clement-marcelin-team-4.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Paris:20241210T143000 DTEND;TZID=Europe/Paris:20241210T153000 DTSTAMP:20241121T144417Z CREATED:20241114T114005Z LAST-MODIFIED:20241121T144417Z UID:48157-1733841000-1733844600@www.bricbordeaux.com SUMMARY:BRIC prestige seminar: Jean-Philippe Girard DESCRIPTION:Jean-Philippe Girard\, Directeur de Recherche INSERM \nCNRS Silver Medal 2013\,\nTeam leader “Biologie Vasculaire: Cellules endothéliales dans l’Immunité\, l’Inflammation et le Cancer”\nIPBS-CNRS (Institut de pharmacologie et de biologie structurale)\, Université de Toulouse\, Toulouse\, France. \nHigh endothelial venules (HEVs) : specialized blood vessels for lymphocyte entry in tumors during cancer immunotherapy \nConference in English.— \nTuesday\, December 10\, 2024\, 2:30 p.m. \nconference room BBS (Bordeaux\, Biologie Santé) 2 rue Dr Hoffmann Martinot – Site Carreire Université de Bordeaux \n  \nKeywords \nTumor microenvironnement\, Tumor-infiltrating lymphocytes\, Cancer immunotherapy \n  \nAbstract \nImmunotherapy\, a therapeutic strategy aimed at increasing the activity of the immune system\, has revolutionized cancer treatment over the past decade. A better understanding of how this therapeutic approach works\, and more particularly how killer lymphocytes access tumors during immunotherapy\, could improve the efficacy of the treatments. We recently discovered the essential role played in this process by specialized blood vessels known as tumor-associated high endothelial venules (TA-HEVs) (Asrir* et al. Cancer Cell 2022). TA-HEVs share important phenotypic and functional characteristics with HEVs in lymph nodes and other lymphoid organs (Moussion and Girard\, Nature 2011 ; Girard et al\, Nature Rev Immunol 2012). For the first time\, we were able to film the lymphocytes infiltrating TA-HEV walls to enter the tumors. We found that increasing the proportion of TA-HEVs in a tumor improves the infiltration of stem-like CD8+ T cells\, the efficacy of the immunotherapy and leads to the eradication of the tumors. Finally\, we showed that the likelihood of recovery of metastatic melanoma patients treated with anti-PD-1 plus anti-CTLA-4 immunotherapy is increased when a large number of TA-HEVs are present in tumors. Together our results suggest that increasing the density of TA-HEVs in human tumors could increase lymphocyte infiltration\, making immunotherapy effective in a greater number of patients. \n \nReferences \nAsrir\, A.*\, Tardiveau; C.*\, Coudert\, J.*\, Laffont\, R.*\, Blanchard\, L.*\, Bellard\, E.\, Veerman\, K.\, Bettini\, S.\, Lafouresse\, F.\, Vina\, E.\, Tarroux\, D.\, Roy\, S.\, Girault\, I.\, Molinaro\, I.\, Martins\, F.\, Scoazec\, J.Y.\, Ortega\, N.\, Robert\, C. and Girard\, J.P. (2022) Tumor-associated HEVs mediate lymphocyte entry into tumors and predict response to PD-1 plus CTLA-4 combination immunotherapy. Cancer Cell\, 40:318-334 (article sélectionné dans ‘Best of Cancer Cell 2022’\, ‘Highly cited article’ du Web of Science; 157 citations dans Google Scholar). \nGirard\, J.P.\, Moussion\, C.\, and Forster\, R. (2012). HEVs\, lymphatics and homeostatic immune cell trafficking in lymph nodes. Nat Rev Immunol 12\, 762-773. \nMoussion\, C.\, and Girard\, J.P. (2011). Dendritic cells control lymphocyte entry to lymph nodes through high endothelial venules. Nature 479\, 542-546. \n  \nBiosketch \nJean-Philippe Girard (PhD) currently holds a position of Senior Research Director at INSERM (French NIH) at IPBS-CNRS\, a large Research Center from the CNRS and the University of Toulouse (France). He received his Ph.D. in Molecular Biology from the University of Toulouse and did his postdoctoral training in Immunology and Vascular Biology at Harvard Medical School (USA) with Pr Tim Springer. Jean-Philippe Girard’s research focuses on the role of high endothelial venules (HEVs) and interleukin-33 (IL-33) in immunity\, inflammation and cancer. He discovered the alarmin cytokine IL-33 as a nuclear factor of HEV (NF-HEV). HEV blood vessels are portals of entry for lymphocytes into lymphoid organs (Moussion and Girard\, Nature 2011; Girard et al\, Nature Rev Immunol 2012). He showed that blood vessels with HEV characteristics designated tumor-associated HEVs are the main sites of lymphocyte entry into tumors\, and are associated with response to immune checkpoint blockade (Asrir* et al Cancer Cell 2022). Dr. Girard is a Highly Cited Researcher in Immunology according to the Web of Science (HCR Index 2023). He received several Scientific Prizes for his work\, including the CNRS Silver Medal (2103)\, and Prizes from the National Academy of Sciences (2012)\, the National Academy of Medecine (2013)\, ‘Fondation pour la Recherche Médicale’ (2016)\, ‘Fondation de France’ (2018) and ‘Fondation ARC’ (2024). \nJean-Philippe Girard is invited by Team 9 Sarcotarget to sit on the jury for Florent Peyraud’s thesis defense on the same day. URL:https://www.bricbordeaux.com/en/event/invited-seminar-jean-philippe-girard/ LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux CATEGORIES:Meetings,Scientific seminars ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/11/prestige-seminar-jean-philippe-girard.jpg END:VEVENT BEGIN:VEVENT DTSTART;VALUE=DATE:20241209 DTEND;VALUE=DATE:20241211 DTSTAMP:20241118T164717Z CREATED:20240415T151530Z LAST-MODIFIED:20241118T164717Z UID:46419-1733702400-1733875199@www.bricbordeaux.com SUMMARY:"Neuro-oncology meets Neuroscience" Symposium DESCRIPTION:\n\n NEURO-ONCOLOGY MEETS NEUROSCIENCE\n \n\n  \n\n\n The Bordeaux Cancer Neuroscience (BCN) Initiative\n \n\nSymposium organized by Andreas Bikfalvi\, Ahmad Sharanek\, Thomas Mathivet\, Lucie Brisson\, Antonio Pagano Zottola équipe 1 de notre unité BRIC\, Valentin Nägerl (Institut interdisciplinaire de neurosciences\, IINS) and Thomas Daubon (Institut de Biochimie et Génétique Cellulaires\, IBGC) \n\nGlioblastoma (GB) is the most aggressive brain tumor characterized by high proliferation rate\, core necrosis\, microvascular proliferation and tumor infiltration. GB treatment consists in tumor resection by surgery and radiotherapy plus concomitant chemotherapy with temozolomide (Stupp et al\, 2005). However\, GB still remains incurable with a low median survival rate of approx. 15 months. This is due to resistance to treatment mainly caused by the presence of tumor cells that escape tumor resection by invading the normal brain parenchyma. Recent developments in immunotherapy did not succeed in overcoming this challenge. Unfortunately\, the mechanisms underlying GB development are still not fully understood and current model systems addressing these questions are not adequate\, impeding progress for the field. It has been shown that the tumor microenvironment (TME) in GB partially controls tumor growth and invasion\, and constitutes a therapeutic target (Bikfalvi et al\, 2022). A body of recent studies points to an important role of the normal neuronal brain environment in GB progression. \n\n\n This meeting brings people together from both\, the neuro-oncology and neuroscience communities to highlight these new developments occurring at the interface between neuro-oncology and the neurosciences.\n \n\n \n The conference is open to the general public with a half-day specifically dedicated to the Patients/Medical Staff/Researchers triptych (in French)\, organized by Sophie North (BRIC-BoRdeaux Institute of onCology).\n \n \n\n\n \n \nAll information and registrations : https://nomn2024.sciencesconf.org/ \nRegistration deadline: December 1st 2024 \nAbstract submission for poster presentation deadline : December 1st 2024 \nAbstract submission for flash poster presentation deadline : November 15th 2024 extended until Friday November 22 URL:https://www.bricbordeaux.com/en/event/neurooncology-meets-neuroscience-symposium/ LOCATION:Institut Broca\, 146 rue leo Saignat\, Bordeaux\, France CATEGORIES:Meetings,Scientific seminars ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/04/symposium-neuro-oncologie-bordeaux-2024-12-910-1.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Paris:20241202T140000 DTEND;TZID=Europe/Paris:20241202T170000 DTSTAMP:20241128T154500Z CREATED:20241128T154500Z LAST-MODIFIED:20241128T154500Z UID:48261-1733148000-1733158800@www.bricbordeaux.com SUMMARY:Thesis defense Guillaume Herrault\, team 6 DESCRIPTION:Cancer Biology thesis defense : Guillaume Herrault\, Team 06 – MIRCADE\, Methods and Innovations for the Research in Pediatric Cancers. \nMonday\, December 2. Closed session \n“Nouvelles stratégies thérapeutiques dans le traitement du gliome infiltrant du tronc cérébral.” \nJury members:\nM. Nicolas LARMONIER\, Professeur des universités\, Université de Bordeaux\, Examinateur\nM. Eddy PASQUIER\, Directeur de recherche\, Aix Marseille Université\, Rapporteur\nMme Isabelle PELLIER\, Professeure des universités – praticienne hospitalière\, Université d’Angers\, Rapporteur\nM. Christophe GROSSET\, Directeur de recherche\, Université de Bordeaux\, Directeur de thèse URL:https://www.bricbordeaux.com/en/event/thesis-defense-guillaume-herrault-team-6/ CATEGORIES:Meetings,Scientific seminars,Thesis defenses ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/11/soutenance-de-these-guillaume-herrault.jpg END:VEVENT BEGIN:VEVENT DTSTART;VALUE=DATE:20241116 DTEND;VALUE=DATE:20241117 DTSTAMP:20241118T095854Z CREATED:20241024T083541Z LAST-MODIFIED:20241118T095854Z UID:48034-1731715200-1731801599@www.bricbordeaux.com SUMMARY:Research opens its doors to you - BRIC participation DESCRIPTION:The Department of Biological and Medical Sciences (SBM) at the University of Bordeaux is opening the doors of its research laboratories to present its scientific and technical activities on Saturday November 16 from 9:30am to 12:30pm and from 2pm to 5pm. \nBâtiment Bordeaux Biologie Santé\, 2 rue Dr Hoffmann Martinot\, BORDEAUX\, Tram A – Arrêt Saint-Augustin \nLink to the event on the SBM Department website \nThe program includes laboratory tours and workshops. \nScientists from our BRIC unit are involved in this event\, which is open to the general public! \nVISITS: \n\n“Les supers pouvoirs des cellules” : Lamia Azzi-Martin (team 4)\, Arnaud Jabouille (team 3)\, Clotilde Billottet (team 3)\n“Voyage au centre d’une biopsie” : Elodie Sifré et Christine Varon (team 4)\n“Visite d’un laboratoire de recherche” : Sandrine Dabernat et Magalie Lalanne (team 8)\n“Extraire votre ADN” : Christelle Dussert and Coralie Genevois (team 4)\, Valérie Le Morvan (team 5)\n“Rencontre avec un habitant de l’estomac” : Lucie Bruhl\, Astrid Ducournau\, Johanna Aptel (team 4)\n\nPOSTERS \n\n“Le poisson zèbre\, précieux allié des chercheurs” : Sandrine Fedou (team 2)\n\nWORKSHOPS \n\nAtelier “Microscopie” : Julie Giraud (team 3)\, Vanessa Desplat (team 10)\nAtelier “Les métiers de la recherche” : Isabelle Vigon (team 10)\, Lucie Brisson (team 1)\, Vanessa Desplat (team 10)\nAtelier “Un poisson nommé Danio” : Sandrine Fedou\, Géraldine Siegfried et Isabelle Auguste (team 2)\n\nWelcome/Departure group \nEmmanuelle Georget (team 1)\, Céline Léon and Grégoire Manaud (team 3)\, Christelle Dussert and Coralie Genevois (team 4)\, Martina Carlotti (team 5)\, Sandrine Dabernat\, Magalie Lalanne and Jessica Massière (team 8)\, Lindita Lari and Blandine Vignau (team 10)\, Valérie Lagarde et Élodie Richard (team 11). \nBravo for the involvement of our colleagues\, welcome to our laboratories! URL:https://www.bricbordeaux.com/en/event/research-opens-its-doors-to-you-bric-participation/ LOCATION:Accueil bâtiment Bordeaux Biologie Santé (BBS)\, 2 rue Dr Hoffmann Martinot\, Bordeaux\, France CATEGORIES:Meetings,Scientific seminars ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/10/portes-ouvertes-sbm-participation-bric.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Paris:20241017T174500 DTEND;TZID=Europe/Paris:20241017T184500 DTSTAMP:20240916T163220Z CREATED:20240916T162141Z LAST-MODIFIED:20240916T163220Z UID:47819-1729187100-1729190700@www.bricbordeaux.com SUMMARY:Michel L. Tremblay - keynote conference of the "3rd Bordeaux Cancer Research Meeting" DESCRIPTION:As part of the “3rd Bordeaux Cancer Research Meeting” seminar organized by our BRIC unit and open to the Oncosphère Nouvelle-Aquitaine community\, we welcome Michel L. Tremblay for a closing lecture. \nThis conference is open to the entire Bordeaux scientific community! \nKeynote Speaker : Michel L. Tremblay \nMcGill Institute – Montréal\, Québec\, Canada \n“Unleashing tyrosine phosphatase gene family clinical impact in immunotherapy” \nMichel L. Tremblay is Professor Honoris Causa of the University of Bordeaux. \n“Holder of more than fifteen patents\, author of over 200 publications in the field of PTPs\, Michel Tremblay is an internationally recognized expert in this area of research.” Click here for his biography. \nPlease note that conference registration is free but mandatory at this link ! \nWe would like to thank the SBM Department of the University of Bordeaux for funding this conference\, as well as all the seminar sponsors: \nOncosphère Nouvelle-Aquitaine\, BD Biosciences\, Bristol Myers Squibb (BMS)\, Casden\, Clinisciences\, Eurofins\, Euromedex\, Li-Cor\, Lonza\, Macherey Nagel\, Merck\, Qiagen\, ThermoFisher\, VectorBuilder\, Discover Echo\, Grosseron\, Nanostring URL:https://www.bricbordeaux.com/en/event/michel-l-tremblay-keynote-conference-of-the-3rd-bordeaux-cancer-research-meeting/ LOCATION:Agora du Haut Carré – Université de Bordeaux\, 43 rue Pierre Noailles\, Talence\, France CATEGORIES:Meetings,Scientific seminars ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/09/michel-tremblay-conference.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Paris:20241017T174500 DTEND;TZID=Europe/Paris:20241017T184500 DTSTAMP:20240916T161451Z CREATED:20240916T153924Z LAST-MODIFIED:20240916T161451Z UID:47804-1729187100-1729190700@www.bricbordeaux.com SUMMARY:Michel Tremblay keynote conference of the 3rd Bordeaux Cancer Research Meeting DESCRIPTION:\n\nDans le cadre du séminaire “3rd Bordeaux Cancer Research Meeting” organisé par notre unité BRIC\, ouvert à la communauté Oncosphère Nouvelle-Aquitaine\, nous accueillons Michel L. Tremblay en conférence de fermeture. \n\nCette conférence est ouverte à toute la communauté scientifique bordelaise ! \nKeynote Speaker \nMichel L. Tremblay \nMcGill Institute – Montréal\, Québec\, Canada \n“Unleashing tyrosine phosphatase gene family clinical impact in immunotherapy” \nMichel Tremblay est professeur Honoris Causa de l’Université de Bordeaux. \n“Détenteur de plus d’une quinzaine de brevets\, auteur de plus de 200 publications dans le domaine des PTPs\, Michel Tremblay est un expert reconnu internationalement dans ce domaine de recherche.” Retrouvez sa biographie à ce lien. \nAttention\, inscription à la conférence gratuite mais obligatoire à ce lien ! \nNous remercions le Département SBM de l’université de Bordeaux pour le financement de cette conférence\, ainsi que tous les sponsors du séminaire : \nOncosphère Nouvelle-Aquitaine\, BD Biosciences\, Bristol Myers Squibb (BMS)\, Casden\, Clinisciences\, Eurofins\, Euromedex\, Li-Cor\, Lonza\, Macherey Nagel\, Merck\, Qiagen\, ThermoFisher\, VectorBuilder\, Discover Echo\, Grosseron\, Nanostring URL:https://www.bricbordeaux.com/en/event/michel-tremblay-keynote-conference-of-the-3rd-bordeaux-cancer-research-meeting/ LOCATION:Agora du Haut Carré – Université de Bordeaux\, 43 rue Pierre Noailles\, Talence\, France CATEGORIES:Scientific seminars ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/09/michel-tremblay-conference.jpg END:VEVENT BEGIN:VEVENT DTSTART;VALUE=DATE:20241017 DTEND;VALUE=DATE:20241018 DTSTAMP:20240908T200518Z CREATED:20240530T134950Z LAST-MODIFIED:20240908T200518Z UID:46787-1729123200-1729209599@www.bricbordeaux.com SUMMARY:3rd Bordeaux Cancer Research Meeting DESCRIPTION:Our Bordeaux-based cancer research institute – BRIC (BoRdeaux Institute of onCology) is organizing a day of conferences open to the Oncosphere Nouvelle-Aquitaine scientific community: The 3rd Bordeaux Cancer Research Meeting. \nPresentations will be grouped in 4 sessions. \n\nTumor Invasion & Metastasis \nTreatments & Resistance \nExploring & Targeting Tumor Microenvironment \nOncoMetabolism \n\n  \nInvited speakers: \nRene Bernards\, Netherlands Cancer Institute (NKI)\, Netherland \nKeynote Speaker: Michel Tremblay\, McGill Institute – Montréal\, Québec\, Canada \n  \n📆 thursday\, october 17 \n📌 Agora du Haut Carré\, 43 Rue Pierre Noailles\, 33400 Talence – Université de Bordeaux \n \nRegistration is free\, but mandatory.\n \n👉 Program and registration at this link \n  \nOrganizing committee \nSamuel Amintas\, Vanessa Desplat\, François Moisan\, Frederic Saltel\, Grégoire Manaud\, Antonio Pagano Zottola \nSarah Lesjean\, Stéphanie Lannelongue\, Sandrine Hamon. URL:https://www.bricbordeaux.com/en/event/3rd-bordeaux-cancer-research-meeting/ LOCATION:Agora du Haut Carré – Université de Bordeaux\, 43 rue Pierre Noailles\, Talence\, France CATEGORIES:Meetings,Scientific seminars ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/05/3r-bordeaux-cancer-research-meeting-18-10-2024-1.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Paris:20241010T140000 DTEND;TZID=Europe/Paris:20241010T170000 DTSTAMP:20241008T131626Z CREATED:20241008T131626Z LAST-MODIFIED:20241008T131626Z UID:47957-1728568800-1728579600@www.bricbordeaux.com SUMMARY:Alexandra Lehmann thesis defense DESCRIPTION:Defense of thesis in Cell Biology and Physiopathology \nAlexandra Lehmann Team 03 – Liver Cancers and Tumor Invasion \nThesis supervision Marion BOUCHECAREILH \n“Dommages au foie associés au Déficit en Alpha 1-Antitrypsine : De la compréhension de la physiopathologie à l’identification d’outils diagnostiques” \nThursday\, October 10 – 2pm \nAmphi BBS – site Carreire 2 rue Dr Hoffmann Martinot – Bordeaux URL:https://www.bricbordeaux.com/en/event/alexandra-lehmann-thesis-defense/ LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux CATEGORIES:Meetings,Scientific seminars,Thesis defenses ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/10/soutenance-de-these-alexandra-lehmann.jpg END:VEVENT BEGIN:VEVENT DTSTART;VALUE=DATE:20241010 DTEND;VALUE=DATE:20241012 DTSTAMP:20240715T075615Z CREATED:20240528T134930Z LAST-MODIFIED:20240715T075615Z UID:46765-1728518400-1728691199@www.bricbordeaux.com SUMMARY:2nd Young Scientist Cancer Congress (YS2C) of the Cancéropôle Grand Sud-Ouest (GSO) DESCRIPTION:The2e Young Scientist Cancer Congress -YS2C of the Cancéropôle Grand Sud-Ouest will take place on October 10-11\, 2024\, in Montpellier. \nThe congress theme “New Translational Approaches in Cancer Therapy” aims to bring together basic\, computational\, and clinical scientists. \nThis congress is especially valuable for PhD students and post-docs\, offering a unique opportunity to present their research alongside an impressive lineup of international keynote speakers: \n\nFrances Balkwill (Barts Cancer Institute\, UK)\nNicholas MacGranahan (University College London\, UK)\nMara Sherman (Memorial Sloan Kettering Cancer Center\, USA)\nDaniela Thommen (The Netherlands Cancer Institute\, NL)\nMichael Schmück-Henneresse (Berlin Institute of Health\, DE)\nCharles Herbaux\, MD\, PhD (CHU de Montpellier\, FR)\nJoanne Clancy (Nature Communications\, UK)\n\nKey submission dates: \n– Oral presentations: July 31\, 2024 (already postponed)\n– Poster presentations: Submit by September 06\, 2024 \nRegistration is free\, but mandatory\, and will be open until September 22\, 2024. \nAll information : https://www.crct-inserm.fr/en/ys2c_2024/. \nThe organising comitee: \nChloé Bessière (CRCT)\, Benoît Aliaga (CRCT)\, Marcin Domagala (CRCT)\, Steffen Fuchs (CRCT)\, Roxana Khazen (CRCT)\, Charline Ogier (CRCT)\, Anna Salvioni (CRCT)\, Pierre-François Roux (IRCM)\, Sara Ovejero (IGH)\, Javier Florido (IRCM)\, Oriana Villafraz (IRCM)\, Katyana Seba (CRBM)\,Thomas Lefeivre (BRIC\, team 10)\, Serena Stadler (Charité Berlin)\, Laura Grunewald (Charité Berlin). URL:https://www.bricbordeaux.com/en/event/2nd-young-scientist-cancer-congress-ys2c-of-the-canceropole-grand-sud-ouest-gso/ LOCATION:Amphi Dumontet – Montpellier\, Place Eugène Bataillon\, Montpellier\, 34095\, France CATEGORIES:Meetings,Scientific seminars ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/05/congres-y2sc-vignette.jpg END:VEVENT BEGIN:VEVENT DTSTART;VALUE=DATE:20241010 DTEND;VALUE=DATE:20241012 DTSTAMP:20240716T070217Z CREATED:20240308T144010Z LAST-MODIFIED:20240716T070217Z UID:45978-1728518400-1728691199@www.bricbordeaux.com SUMMARY:Microenvironment and immunotherapy of sarcomas - Second edition Symposium DESCRIPTION:The 2ᵈᵉ edition of the “Microenvironment and Immunotherapy of Sarcomas” symposium will take place from Thursday\, October 10\, 2024 (from 1:30pm) to Friday\, October 11\, 2024\, at the Palais de la Bourse in Bordeaux. \nIt is organized within the framework of the University Hospital Research Program (RHU\, ANR) – RHU Condor coordinated by Pr Antoine Italiano\, head of team 9 – Sarcotarget. \nA call for papers is open to the entire scientific community for presentation of work in mini-oral or poster format (costs incurred will be covered for those selected). \nRegistrations are also open. \nAbstract submission deadline: June 30\, 2024 \nApplication deadline: September 27\, 2024 \nInformation and registration at this link URL:https://www.bricbordeaux.com/en/event/microenvironment-and-immunotherapy-of-sarcomas-second-edition-symposium/ LOCATION:Palais de la Bourse\, Bordeaux\, 17 place du Palais de la Bourse\, Bordeaux\, France CATEGORIES:Meetings,Scientific seminars ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/03/vignette-save-the-date-symposium-sarcomas-2024.jpg ORGANIZER;CN="RHU Condor":MAILTO:contact@condorprogram.com END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Paris:20240927T140000 DTEND;TZID=Europe/Paris:20240927T170000 DTSTAMP:20240903T092948Z CREATED:20240903T092948Z LAST-MODIFIED:20240903T092948Z UID:47866-1727445600-1727456400@www.bricbordeaux.com SUMMARY:Elisabeth Lata thesis defense DESCRIPTION:PhD specialization: Genetics \nElisabeth Lata\, Team 07 – Targeting Transcription in Breast Cancer.. \nSupervisor Martin Teichmann \nL’isoforme embryonnaire de l’ARN polymérase III humaine : son rôle dans la transformation tumorale et l’établissement de métastases. \nAmphithéâtre B Faculté d’odontologie\,\n146 rue Léo Saignat\, 33076 Bordeaux \n\nNotice of defense with abstract and jury members at this link URL:https://www.bricbordeaux.com/en/event/elisabeth-lata-thesis-defense/ LOCATION:Amphi B\, faculté Odontologie\, 146 rue Léo Saignat\, Bordeaux\, France CATEGORIES:Meetings,Scientific seminars,Thesis defenses ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/09/soutenance-de-these-elisabeth-lata.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Paris:20240923T140000 DTEND;TZID=Europe/Paris:20240923T170000 DTSTAMP:20240902T092908Z CREATED:20240902T092647Z LAST-MODIFIED:20240902T092908Z UID:47677-1727100000-1727110800@www.bricbordeaux.com SUMMARY:Soutenance de thèse Adèle Delamarre DESCRIPTION:Thesis defense in Cancer Biology Adèle Delamarre Team 03 – Liver Cancers and Tumor Invasion.Thesis supervisor Victor De Ledinghen Monday\, September 23 – 2pm BBS Amphi 2 rue Dr H. Martinot – Bordeaux (Carreire) “Metabolic steatopathy and hepatocellular carcinoma: prediction of carcinogenesis to treatment response by proteomic profiling.” URL:https://www.bricbordeaux.com/en/event/soutenance-de-these-adele-delamarre/ LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux CATEGORIES:Meetings,Scientific seminars,Thesis defenses ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/09/soutenance-de-these-adele-delamarre.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Paris:20240918T140000 DTEND;TZID=Europe/Paris:20240918T170000 DTSTAMP:20240916T160531Z CREATED:20240916T160531Z LAST-MODIFIED:20240916T160531Z UID:47811-1726668000-1726678800@www.bricbordeaux.com SUMMARY:HDR defense Monica Arnedos Ballester DESCRIPTION:HDR defense “Habilitation à Diriger la Recherche” in Life and Health Sciences \nMonica ARNEDOS BALLESTER Team 07 – Targeting Transcription in Breast Cancer. \n“La recherche translationnelle dans le cancer du sein : vers une personnalisation des traitements.” \nWednesday\, September 18\, 2024 at 2 p.m. \nLibrary/meeting room\, Institut Bergonié. 229 cr Argonne\, Bordeaux URL:https://www.bricbordeaux.com/en/event/hdr-defense-monica-arnedos-ballester/ LOCATION:Institut Bergonié\, 229 Cours de l'Argonne\, Bordeaux\, 33076\, France CATEGORIES:Meetings,Scientific seminars ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/09/soutenance-hdr-monica-arnedos.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Paris:20240910T093000 DTEND;TZID=Europe/Paris:20240910T110000 DTSTAMP:20240908T201411Z CREATED:20240715T110235Z LAST-MODIFIED:20240908T201411Z UID:47424-1725960600-1725966000@www.bricbordeaux.com SUMMARY:Invited seminar – Pr. Tapas Kundu - 2024-09-10 DESCRIPTION:Martin Teichmann\, Team 07 – Targeting Transcription in Breast Cancer\, invites Pr. Tapas Kundu to present a seminar. \nPr Tapas Kundu \nTranscription and Disease Laboratory\, Molecular Biology and Genetics Unit\, Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) – India \n  \nChromatin meets autophagy: A tale of nonhistone chromatin protein mediated genome organization and transcription regulation \nThe eukaryotic genome is intricately organized on a beads-on-string structure into nucleoprotein filaments. These filamentous structures consist of nucleosome beads\, composed of approximately 147 base pairs of DNA and four octameric core histones. The folding pattern of these nucleosomes varies depending on the cellular state\, ensuring the overall stability and balance within the organism. In addition to DNA and histones\, various non-histone chromatin-associated proteins along with RNA molecules also play crucial roles in fine-tuning the organization and function of the genome. Our laboratory discovered that a highly abundant nuclear protein\, human transcription coactivator PC4\, is a non-histone component involved in the genome organization\, stability\, and maintenance of the epigenetic state. By employing atomic force and electron microscopy\, we have demonstrated that PC4 directly interacts with core histones and linker histone H1 thus compacting the genome very efficiently. Our experimental results obtained from ATAC-Seq and RNA-Seq analysis provide valuable insights into the regulatory role of PC4 in genome organization. We observed that when PC4 is absent\, there is a significant increase in genome decompaction accompanied by hyper-acetylation levels and abnormal gene expression patterns. Interestingly\, we discovered that embryonic development was impaired in mice lacking PC4\, indicating its essential role for survival. However\, intriguingly\, cell lines with reduced levels of PC4 exhibited enhanced cell proliferation rates and demonstrated resistance to radiation exposure. Further investigation revealed that the mechanism behind this radiation resistance involves the upregulation of autophagy pathways upon depletion of PC4. Remarkably\, our ATAC-Seq data unveiled pervasive genomic decompaction coupled with heightened acetylation specifically at multiple loci related to autophagy-associated genes within these knockdown cells. A similar occurrence was observed in both brain and spleen-specific knockout models of PC4 in mice as well as C. elegans. However\, it is worth noting that the brain-specific knockout of PC4 did not exhibit a pronounced phenotype apart from noticeable impairments in memory extinction. Interestingly\, when PC4 was absent\, there was a significant increase in the expression level of another non-histone protein that interacts with PC4. We intend to further investigate the primary role of this complex involving PC4 in heterochromatinization and its subsequent physiological functions. \n  \n📌 BBS conference room\, 2 rue Dr Hoffamnn Martinot – Bordeaux \n  \n📆 10/09/2024\, 9h30 \n  \nBiography \nProfessor\nSir J. C. Bose National Fellow Silver Jubilee Professor (2015-16) Transcription and Disease Laboratory Molecular Biology and Genetics Unit JNCASR\, Jakkur P.O.\, Bangalore -560064\, India Ph: 91-80-2208 2679 / 2840/ 41\, Mobile: 09449456334. Email: tapas@jncasr.ac.in \nFormer Director\nCSIR- Central Drug Research Institute\, Lucknow \nAdjunct Professor\,\nSpecial Centre for Molecular Medicine\,\nJawaharlal Nehru University\, New Delhi \nLifetime Distinguished Professor\nUniversity of Mysore\, Karnataka \nDistinguished Visiting Professor\nSDU Academy of Higher Education and Research\,\nKarnataka\, India \nDistinguished Visiting Professor\nIndian Institute of Technology\, Bombay \n  \nProf. Tapas Kumar Kundu completed his master’s degree in Biochemistry from the University of Agricultural Sciences\, Bangalore in 1989\, winning a gold medal for standing first in the master’s degree examination. He was awarded his Ph.D. from the Indian Institute of Science\, Bangalore\, in the year 1995 with the best thesis award. Following his Ph.D.\, he had a short stint as a visiting foreign research associate in the National Institute of Genetics\, Mishima\, Japan\, followed by a post-doctoral fellowship at the Rockefeller University\, USA (1996-99). He joined JNCASR as in 1999. Prof. Kundu has made significant contributions in the area of regulation of gene expression and its link to disease and therapeutics. He is not only elucidating the mechanisms of transcription regulation through the epigenetic modifications but also targeting them to design new generation diagnostics\, as well as therapeutics. Over the years\, he has published several research papers in many international journals. Several patent applications from the laboratory have been granted and some are under process\, which include several academically important research reagents with potential commercial values\, some of which have already been commercialized by renowned companies. He is a fellow of four major national academies of India and served as an editorial board member of the Journal of Biological Chemistry (JBC) from 2011-2016. Presently\, he is serving as an “Associate Editor” of the Journal of Biochemistry (Oxford University Press)\, Series Editor of Subcellular Biochemistry (Springer Nature)\, and the reviewing Editor of eLife Journal. As a Director of CSIR-CDRI\, Lucknow\, Prof. Kundu initiated many relevant academic and drug development programs. Under his leadership\, several drug molecules reached Phase-I clinical trials and could be licensed to industries for further development. He also led and completed Phase-III clinical trials for anti-Covid 19 therapy which is awaiting DCGI approval. He was instrumental to establish the ‘Asian Forum for Chromatin and Chromosome Biology and ‘Chemical Biology Society\, India’. Besides fundamental research\, Prof. Kundu is also involved in teaching and organizing science outreach programs. His popular lectures on ‘Genes\, Disease and Therapeutics’ have benefitted high school and college students greatly. \n  \nHe is the recipient of several awards\, noteworthy among which are: the Shanti Swarup Bhatnagar Prize from CSIR (2005)\, the National Academy of Science\, India- Reliance Industries Platinum Jubilee Award (2008)\, the Sir JC Bose National Fellowship from DST (2010)\, the GD Birla award for scientific research (2011)\, The Ranbaxy Research Award 2011 in the field of Medical Sciences – Basic Research and India Innovation Award 2012 given by Merck Millipore 2012 (First place)\, Shri Om Prakash Bhasin Award for the year 2019 in the field of Health Medical Sciences by the Shri Om Prakash Bhasin Foundation\, New Delhi\, Sir M. Visvesvaraya Lifetime Achievement Award for Senior Scientists / Engineers (2021)\, and ICBS-2022 Global Lectureship Award by International Chemical Biology Society (ICBS). \n  URL:https://www.bricbordeaux.com/en/event/invited-seminar-pr-tapas-kundu-2024-09-10/ LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux CATEGORIES:Meetings,Scientific seminars ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/07/invited-seminar-tapas-kundu.jpg END:VEVENT BEGIN:VEVENT DTSTART;VALUE=DATE:20240831 DTEND;VALUE=DATE:20240901 DTSTAMP:20240808T135947Z CREATED:20240806T143657Z LAST-MODIFIED:20240808T135947Z UID:47571-1725062400-1725148799@www.bricbordeaux.com SUMMARY:Alpha 1-Antitrypsin deficiency - siRNA treatments - Information meeting DESCRIPTION:Marion Bouchecareilh\, CR CNRS team 8\, is organizing an information and exchange day for patients with Alpha 1-Antitrypsin deficiency concerning siRNA treatments for the liver damage associated with this deficiency\, on Saturday August 31\, 2024 in Bordeaux (Campus Bordeaux Pey-Berland). The aim of this event\, which will be attended by a number of French experts\, is to present and explain to patients the mode of action of siRNA treatments\, the various clinical trials currently underway and their modalities\, and feedback on this type of treatment for other pathologies. The aim of this meeting is to provide an opportunity for exchange and sharing between patients\, patient associations and the various players involved in understanding and combating the symptoms associated with this deficiency. Program available at this link Hybrid format. Free but mandatory registration before August 15 at this link  Interview with Dr Marion Bouchecareilh for FilFoie\, partner of this event\, available at this link. \nDr Marion Bouchecareilh presents the rare disease she is studying: Alpha 1-Antitrypsin deficiency\, and the ongoing Phase 3 clinical trial involving siRNA treatment of liver damage associated with this deficiency. She also takes advantage of this interview to talk about the projects she is developing concerning primary hepatopathies and cancers of the liver associated with Alpha 1-Antitrypsin deficiency. Dr Bouchecareilh is leading the latter project in partnership with Dr Samuel Amintas\, MCU-PH also in BRIC team 8. URL:https://www.bricbordeaux.com/en/event/alpha-1-antitrypsin-deficiency-sirna-treatments-information-meeting/ LOCATION:Pôle Juridique et judiciaire de l’Université de Bordeaux\, 35 place Pey Berland\, Bordeaux\, France CATEGORIES:Meetings,News,Scientific seminars ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/08/journee-deficit-alpha-1-antitrypsine-.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Paris:20240716T110000 DTEND;TZID=Europe/Paris:20240716T120000 DTSTAMP:20240712T103634Z CREATED:20240704T125926Z LAST-MODIFIED:20240712T103634Z UID:47308-1721127600-1721131200@www.bricbordeaux.com SUMMARY:Invited seminar - Pr. Alain Gobert - 2024-07-16 DESCRIPTION:Christine Varon\,team 04 – Helicobacter-associated digestive cancers\, cancer stem cells and therapeutic strategies \, invites Pr Alain Gobert to present a seminar. \nPr Alain Gobert\nResearch Professor of Medicine\, Division of Gastroenterology\, Hepatology and Nutrition\, Center for Mucosal Inflammation and Cancer\, Vanderbilt University Medical Center\nNashville\, TN\, USA \nRole of polyamines and electrophilic stress in gastrointestinal carcinogenesis: Therapeutic implications. \nGastric cancer (GC) is the fourth leading cause of cancer death worldwide. The intestinal type of GC is initiated by the pathogen Helicobacter pylori\, which infects half of the world’s population. The three biogenic polyamines\, putrescine\, spermidine\, and spermine play key functions in a variety of cellular processes and are essential for cellular homeostasis. Using animal models of H. pylori-mediated diseases\, we showed that the enzyme spermine oxidase (SMOX)\, which back-converts spermine to spermidine\, plays a major role in development of gastritis and gastric dysplasia. This occurs notably through the generation of acrolein\, a reactive aldehyde that initiates lipid peroxidation and further generation of bifunctional electrophiles. A potent scavenger of these molecules attenuates gastric carcinogenesis. Similar results were then obtained in models of sporadic or colitis-associated colorectal cancers. \n📌 BBS conference room\, 2 rue Dr Hoffamnn Martinot – Bordeaux \n📆 16/07/2024\, 11 am URL:https://www.bricbordeaux.com/en/event/invited-seminar-pr-alain-gobert-2024-07-16/ LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux CATEGORIES:Meetings,Scientific seminars ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/07/invited-seminar-alain-gobert-1.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Paris:20240702T140000 DTEND;TZID=Europe/Paris:20240702T170000 DTSTAMP:20240628T133356Z CREATED:20240610T143409Z LAST-MODIFIED:20240628T133356Z UID:46960-1719928800-1719939600@www.bricbordeaux.com SUMMARY:Lydia Dif thesis defense DESCRIPTION:Lydia Dif\, Team 03 – Liver Cancers and Tumor Invasion. \nThesis direction Violaine Moreau \n“La fascine-1 en tant que cible thérapeutique dans l’hepatoblastome.” \n📆 Tuesday\, July 2\, 2pm \n📌 Amphi BBS\, 2 rue du Docteur Hoffmann Martinot Bordeaux (Carreire) \nNotice of defense with abstract available at this link URL:https://www.bricbordeaux.com/en/event/lydia-dif-thesis-defense/ LOCATION:amphithéatre du BBS\, 2 rue Dr Hoffmann Martinot\, Bordeaux\, France CATEGORIES:Meetings,Scientific seminars,Thesis defenses ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/06/soutenance-de-these-lydia-dif.jpg END:VEVENT BEGIN:VEVENT DTSTART;VALUE=DATE:20240620 DTEND;VALUE=DATE:20240621 DTSTAMP:20240617T125331Z CREATED:20240216T155252Z LAST-MODIFIED:20240617T125331Z UID:45841-1718841600-1718927999@www.bricbordeaux.com SUMMARY:3D Biology Models Day June 20\, 2024 DESCRIPTION:Christine Varon\, head of team 04 (Digestive cancers associated with Helicobacter infection\, cancer stem cells and therapeutic strategies) and her scientific colleagues from Bordeaux are organizing a day of 3D models in biology. \n📆 June 20\, 2024 \n📌Domaine du Haut Carré \n👉 Free registration and abstract submission at this link:https://3dbio.sciencesconf.org/ \nThe deadline for registration and abstract submission has been extended to June 6. \nGreat news\, in addition to our great local speakers\, we will have the pleasure to welcome Xavier Gidrol (CEA Grenoble)\, one of the project leader of the recently granted PEPR MEDOOC! \nThe focus of the day is on three-dimensional cellular models developed in vitro for biology and medicine. These models\, which include organoids\, spheroids\, organs-on-a-chip and bioprinted tissues\, are currently undergoing exponential development\, thanks in particular to the coincidence between advances in stem cell biology and technologies enabling the topology and composition of the tissue microenvironment to be controlled. As well as being an alternative to animal models\, these models are of major interest for understanding developmental mechanisms\, disease modeling\, drug screening\, regenerative medicine and personalized medicine. This research is intrinsically interdisciplinary\, requiring the collaboration of biologists\, physicians\, physicists\, chemists and engineers. \nThe aim of this first edition is to bring together people already using or wishing to develop these models\, to share their current or future projects. The day will enable the various local players to interact with each other\, pool their efforts and promote exchanges and collaborations. \nPractical information \nThe day will be organized around thematic sessions\, with one invited paper and short communications (8 min + 2 min questions) per session. Coffee and lunch breaks will be accompanied by poster sessions. Abstracts for short communications and/or posters will be accepted from 15/02/2024. \nOn-site only \nOrganizing committee \nHugo De-Oliveira (Biotis) – Isabelle Dupin (CRCTB) – Elise Maurat (CRCTB) – Matthieu Raoux (CBMN) – Gaëlle Recher (LP2N) – Vincent Studer (IINS) – Christine Varon (BRIC) URL:https://www.bricbordeaux.com/en/event/3d-biology-models-day-june-20-2024/ LOCATION:Agora du Haut Carré – Université de Bordeaux\, 43 rue Pierre Noailles\, Talence\, France CATEGORIES:Meetings,Scientific seminars ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/02/vignette-1.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Paris:20240617T133000 DTEND;TZID=Europe/Paris:20240617T170000 DTSTAMP:20240628T133415Z CREATED:20240607T095518Z LAST-MODIFIED:20240628T133415Z UID:46950-1718631000-1718643600@www.bricbordeaux.com SUMMARY:HDR defense Sandrine Poglio DESCRIPTION:Sandrine Poglio\, univ. lecturerTeam 05 – Translational Research In Oncodermatology and Orphan skin diseases (TRIO2). will defend her HDR (Habilitation à Diriger la Recherche) on Monday June 17 at 1:30pm in the amphitheatre of the Centre de Génomique Fonctionnelle de Bordeaux\, site Carreire Université de Bordeaux (146 rue Leo Saignat). \n“Des cellules souches hématopoïétiques aux lymphocytes T tumoraux” \nJury members: \nPr Katia Boniface\, PR\, Université de Bordeaux\nDr Erika Brunet\, DR INSERM\, Institut Imagine\, Paris\nDr Françoise PFLUMIO\, DR INSERM\, Laboratoire LSHL\, CEA-INSERM\, Fontenay-aux Roses\nDr Laurent Genestier\, DR INSERM\, CIRI\, Lyon\nPr Nicolas Ortonne\, PU-PH\, IMRB\, APHP\, Département de Pathology Hôpital Henri Mondor\, Créteil\nPr Jean-Philippe Merlio\, PU-PH\, CHU et Université de Bordeaux URL:https://www.bricbordeaux.com/en/event/hdr-defense-sandrine-poglio/ LOCATION:salle de conférence CGFB – site Carreire\, 146 rue Leo Saignat\, Bordeaux\, 33000\, France CATEGORIES:Meetings,Scientific seminars ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/06/soutenance-hdr-sandrine-poglio.jpg END:VEVENT BEGIN:VEVENT DTSTART;VALUE=DATE:20240617 DTEND;VALUE=DATE:20240618 DTSTAMP:20240404T140706Z CREATED:20240404T140706Z LAST-MODIFIED:20240404T140706Z UID:46420-1718582400-1718668799@www.bricbordeaux.com SUMMARY:Science\, society and values symposium DESCRIPTION:Science\, society and values symposium at Agora du Haut-Carré\, Talence. \nPr Andreas Bikfalvi (team1) is part of the organization of this symposium. \nFree admission with registration : https://form.jotform.com/240513496727360 \nProgram: \nSYMPOSIUM SCIENCE-SOCIETY VALUES-PROGRAM-final URL:https://www.bricbordeaux.com/en/event/science-society-and-values-symposium/ LOCATION:Agora du Haut Carré – Université de Bordeaux\, 43 rue Pierre Noailles\, Talence\, France CATEGORIES:Meetings,Scientific seminars ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/04/afiiche-symposium-science-societe-valeurs-juin-2024.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Paris:20240614T143000 DTEND;TZID=Europe/Paris:20240614T170000 DTSTAMP:20240613T145205Z CREATED:20240528T123755Z LAST-MODIFIED:20240613T145205Z UID:46756-1718375400-1718384400@www.bricbordeaux.com SUMMARY:Thesis defense Alexia Calovoulos DESCRIPTION:Alexia Calovoulos\, team 6 MIRCADE (Methods and Innovations for the Research in Pediatric Cancers) will present her thesis in Cell Biology and Pathophysiology.. \nThesis supervisor Christophe Grosset. \nTitle : “Study of the three-dimensional organization of hepatoblastoma tissues by volumetric imaging: Link to the Wnt/beta-catenin signaling pathway?” \n📆 Friday\, June 14 at 2:30 p.m. \nModule 2.6 batiment CROUS 2e étage (Carreire)\n146 rue Léo Saignat Bordeaux \nNotice of defense with abstract at this link \nThesis funded by the Région Nouvelle-Aquitaine and the Eva pour la Vie and Sphères associations. URL:https://www.bricbordeaux.com/en/event/thesis-defense-alexia-calovoulos/ CATEGORIES:Meetings,Scientific seminars,Thesis defenses ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/05/soutenance-de-these-alexia-calovoulos.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Paris:20240613T120000 DTEND;TZID=Europe/Paris:20240613T130000 DTSTAMP:20240614T081857Z CREATED:20240425T161311Z LAST-MODIFIED:20240614T081857Z UID:46427-1718280000-1718283600@www.bricbordeaux.com SUMMARY:BRIC technology seminar - Promega DESCRIPTION:Our Technologies Group organizes this seminar with Promega \n  \nEnhancing your Research using Bioluminescent Technologies \nPresentation by Promega France :\nLudivine Sinzelle\, Key account Manager\, Responsable Grands Comptes Sud-Ouest\nFlorian Mignot\, Technical Support for Drug Discovery Solutions \nDetails in the poster. \n \n  \n  \n  URL:https://www.bricbordeaux.com/en/event/bric-technology-seminar-promega/ LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux CATEGORIES:Meetings,Scientific seminars ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/04/vignette-bric-techno-meeting-promega-bis.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Paris:20240612T140000 DTEND;TZID=Europe/Paris:20240612T150000 DTSTAMP:20240610T133646Z CREATED:20240531T133015Z LAST-MODIFIED:20240610T133646Z UID:46836-1718200800-1718204400@www.bricbordeaux.com SUMMARY:SBM Department Seminar - Maxime Mahout DESCRIPTION:Maxime Mahout \n“Décomposition des flux métaboliques des cellules en prolifération en Modes Elémentaires de Flux (EFMs). Application à la cellule cancéreuse moyenne” \n  \n📆 Wednesday June 12 at 2pm \n📌 ATTENTION ROOM CHANGE: amphitheatre in the BBS building\, 2 rue Dr Hoffmann Martinot\, Bordeaux\n \nSeminar organized by the Department of Biological and Medical Sciences (SBM) at the University of Bordeaux. URL:https://www.bricbordeaux.com/en/event/sbm-department-seminar-maxime-mahout/ LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux CATEGORIES:Meetings,Scientific seminars ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/05/seminaires-departement-sbm.jpg END:VEVENT END:VCALENDAR