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X-WR-CALDESC:Events for Bordeaux Institute of Oncology
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DTSTART;TZID=Europe/Paris:20240702T140000
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DTSTAMP:20240628T133356Z
CREATED:20240610T143409Z
LAST-MODIFIED:20240628T133356Z
UID:46960-1719928800-1719939600@www.bricbordeaux.com
SUMMARY:Lydia Dif thesis defense
DESCRIPTION:Lydia Dif\, Team 03 – Liver Cancers and Tumor Invasion. \nThesis direction Violaine Moreau \n“La fascine-1 en tant que cible thérapeutique dans l’hepatoblastome.” \n📆 Tuesday\, July 2\, 2pm \n📌 Amphi BBS\, 2 rue du Docteur Hoffmann Martinot Bordeaux (Carreire) \nNotice of defense with abstract available at this link
URL:https://www.bricbordeaux.com/en/event/lydia-dif-thesis-defense/
LOCATION:amphithéatre du BBS\, 2 rue Dr Hoffmann Martinot\, Bordeaux\, France
CATEGORIES:Meetings,Scientific seminars,Thesis defenses
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/06/soutenance-de-these-lydia-dif.jpg
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DTSTART;TZID=Europe/Paris:20240716T110000
DTEND;TZID=Europe/Paris:20240716T120000
DTSTAMP:20240712T103634Z
CREATED:20240704T125926Z
LAST-MODIFIED:20240712T103634Z
UID:47308-1721127600-1721131200@www.bricbordeaux.com
SUMMARY:Invited seminar - Pr. Alain Gobert - 2024-07-16
DESCRIPTION:Christine Varon\,team 04 – Helicobacter-associated digestive cancers\, cancer stem cells and therapeutic strategies \, invites Pr Alain Gobert to present a seminar. \nPr Alain Gobert\nResearch Professor of Medicine\, Division of Gastroenterology\, Hepatology and Nutrition\, Center for Mucosal Inflammation and Cancer\, Vanderbilt University Medical Center\nNashville\, TN\, USA \nRole of polyamines and electrophilic stress in gastrointestinal carcinogenesis: Therapeutic implications. \nGastric cancer (GC) is the fourth leading cause of cancer death worldwide. The intestinal type of GC is initiated by the pathogen Helicobacter pylori\, which infects half of the world’s population. The three biogenic polyamines\, putrescine\, spermidine\, and spermine play key functions in a variety of cellular processes and are essential for cellular homeostasis. Using animal models of H. pylori-mediated diseases\, we showed that the enzyme spermine oxidase (SMOX)\, which back-converts spermine to spermidine\, plays a major role in development of gastritis and gastric dysplasia. This occurs notably through the generation of acrolein\, a reactive aldehyde that initiates lipid peroxidation and further generation of bifunctional electrophiles. A potent scavenger of these molecules attenuates gastric carcinogenesis. Similar results were then obtained in models of sporadic or colitis-associated colorectal cancers.       \n📌 BBS conference room\, 2 rue Dr Hoffamnn Martinot – Bordeaux \n📆 16/07/2024\, 11 am
URL:https://www.bricbordeaux.com/en/event/invited-seminar-pr-alain-gobert-2024-07-16/
LOCATION:Salle de conférence BBS (Bordeaux Biologie Santé)\, 2 rue Dr Hoffmann Martinot\, Bordeaux
CATEGORIES:Meetings,Scientific seminars
ATTACH;FMTTYPE=image/jpeg:https://cdn-bricbordeaux.onlc.eu/wp-content/uploads/2024/07/invited-seminar-alain-gobert-1.jpg
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