{"id":43687,"date":"2023-01-20T00:00:00","date_gmt":"2023-01-19T23:00:00","guid":{"rendered":"https:\/\/www.bricbordeaux.com\/2023\/01\/figaro-article-crispr-f-moreau-gaudry-and-a-bedel-intervention\/"},"modified":"2023-07-07T12:41:04","modified_gmt":"2023-07-07T10:41:04","slug":"figaro-article-crispr-f-moreau-gaudry-and-a-bedel-intervention","status":"publish","type":"post","link":"https:\/\/www.bricbordeaux.com\/en\/2023\/01\/figaro-article-crispr-f-moreau-gaudry-and-a-bedel-intervention\/","title":{"rendered":"Figaro article – CRISPR – F. Moreau-Gaudry and A. bedel intervention"},"content":{"rendered":"
Pr Fran\u00e7ois Moreau-Gaudry<\/a> and Dr Aur\u00e9lie Bedel<\/a> of Team 8 – Genetic Biotherapies and Oncology (BioGO)<\/a>, specialists in the study of genotoxicity induced by CRISPR-Cas9 testify in the Figaro article of 20\/01\/2023 on CRISPR technology.<\/div>\n
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“The CRISPR revolution keeps its promises<\/em>“, headlines Le Figaro.<\/em> Ten years after its discovery, the genome editing tool has opened up exciting prospects for medicine. \u00ab The applications of CRISPR are too numerous to list extensively<\/em> \u00bb,notes American Jennifer Doudna, a professor at the University of California, Berkeley, who developed the technique with Frenchwoman Emmanuelle Charpentier, director of the Max Planck Research Center for Pathogen Science in Berlin. Jennifer Doudna publishes an article in the journal Science<\/em> reviewing the last ten years of CRISPR-Cas9 technology. But as with any medical innovation, however exciting it may be, there are undesirable effects to be feared, or at least monitored. This is the expertise developed by the Inserm team of Prof. Fran\u00e7ois Moreau-Gaudry and Dr. Aur\u00e9lie Bedel (U1312 Biotherapies of genetic diseases and cancers) at the University of Bordeaux. \u00ab Very quickly, it was observed that CRISPR was less precise than expected: this is called the ‘off-target’ effect, i.e. the scissors sometimes hit the wrong target or cause changes in the chromosome,\u00bb<\/em> explains Prof. Moreau-Gaudry. \u00ab This is of concern to us because these are molecular events that are found in cancer<\/em> \u00bb, explains Aur\u00e9lie Bedel. This does not imply the suspension of ongoing trials, she adds.<\/div>\n
Extract from the Inserm press review of 20\/01<\/a><\/strong><\/div>\n
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Link to the online article.<\/strong><\/a><\/div>\n
Link to the pdf of the article.<\/strong><\/a><\/div>\n
BioGO team page.<\/strong><\/a><\/div>\n","protected":false},"excerpt":{"rendered":"

Pr Fran\u00e7ois Moreau-Gaudry and Dr Aur\u00e9lie Bedel of Team 8 – Genetic Biotherapies and Oncology (BioGO), specialists in the study of genotoxicity induced by CRISPR-Cas9 testify in the Figaro article of 20\/01\/2023 on CRISPR technology. “The CRISPR revolution keeps its promises“, headlines Le Figaro. Ten…<\/p>\n","protected":false},"author":3,"featured_media":42576,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[111],"tags":[],"class_list":["post-43687","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/www.bricbordeaux.com\/en\/wp-json\/wp\/v2\/posts\/43687","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.bricbordeaux.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bricbordeaux.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bricbordeaux.com\/en\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bricbordeaux.com\/en\/wp-json\/wp\/v2\/comments?post=43687"}],"version-history":[{"count":1,"href":"https:\/\/www.bricbordeaux.com\/en\/wp-json\/wp\/v2\/posts\/43687\/revisions"}],"predecessor-version":[{"id":44182,"href":"https:\/\/www.bricbordeaux.com\/en\/wp-json\/wp\/v2\/posts\/43687\/revisions\/44182"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.bricbordeaux.com\/en\/wp-json\/wp\/v2\/media\/42576"}],"wp:attachment":[{"href":"https:\/\/www.bricbordeaux.com\/en\/wp-json\/wp\/v2\/media?parent=43687"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bricbordeaux.com\/en\/wp-json\/wp\/v2\/categories?post=43687"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bricbordeaux.com\/en\/wp-json\/wp\/v2\/tags?post=43687"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}